Every outcome DoseRank ranks
Start with the result you want. Explore the active outcome catalog, then open its evidence-based product ranking.
Sleep Better
7Fall asleep faster and wake up refreshed.
Decrease sleep latency
Sleep Better
Time needed to fall asleep.
Improve sleep quality
Sleep Better
Overall restfulness and perceived quality of sleep.
Increase alertness
Sleep Better
Wakefulness and readiness to respond.
Increase sleep duration
Sleep Better
Total amount of sleep obtained.
Reduce daytime sleepiness
Sleep Better
Excessive sleepiness or reduced alertness during the day.
Reduce insomnia
Sleep Better
Degree of difficulty initiating or maintaining sleep.
Reduce night awakenings
Sleep Better
Frequency of waking during the night.
Boost Energy
5Beat fatigue and feel energized all day.
Increase energy
Boost Energy
Subjective sense of energy, drive, or liveliness.
Increase ketone levels
Boost Energy
Circulating ketone concentrations, relevant in fasting or ketogenic states.
Increase thermogenesis
Boost Energy
Heat production and metabolic energy expenditure.
Reduce cachexia
Boost Energy
Disease-related weight and muscle loss often seen in chronic illness or cancer.
Reduce fatigue
Boost Energy
Persistent tiredness, low stamina, or lack of energy.
Immune Support
11Strengthen your defenses against colds and bugs.
Improve immune tolerance
Immune Support
Balanced immune regulation without excessive reactivity.
Improve vaccine response
Immune Support
Antibody or immune response after vaccination.
Improve zinc status
Immune Support
Biochemical sufficiency of zinc.
Normalize white blood cell count
Immune Support
Number of circulating immune cells.
Reduce anaphylaxis risk
Immune Support
Severe, potentially life-threatening allergic reaction.
Reduce autoimmune activity
Immune Support
Clinical or biomarker activity of autoimmune disease.
Reduce bad breath
Immune Support
Bad breath or unpleasant oral odor.
Reduce colds
Immune Support
Frequency of upper respiratory infections resembling the common cold.
Reduce infections
Immune Support
Overall rate of infectious illness.
Shorten colds
Immune Support
Length of cold episodes.
Shorten infections
Immune Support
Length of infectious illness episodes.
Calm & Mood
9Ease stress and lift your mood.
Improve mood
Calm & Mood
Overall emotional state.
Improve stress resilience
Calm & Mood
Ability to cope with or recover from stress.
Increase calmness and relaxation
Calm & Mood
Reduced tension and greater sense of calm.
Reduce agitation and restlessness
Calm & Mood
Undesired activation, jitteriness, or inner restlessness.
Reduce anxiety
Calm & Mood
Worry, tension, fear, or related anxiety manifestations.
Reduce burnout symptoms
Calm & Mood
Exhaustion, reduced resilience, and work-related strain.
Reduce depressive symptoms
Calm & Mood
Low mood, anhedonia, and related depressive features.
Reduce irritability
Calm & Mood
Low threshold for frustration or anger.
Reduce stress
Calm & Mood
Subjective experience of stress or overload.
Focus & Memory
19Sharpen focus, memory, and mental clarity.
Improve cognitive function
Focus & Memory
Overall thinking ability including memory, attention, and processing.
Improve coordination
Focus & Memory
Control and precision of movement.
Improve focus and concentration
Focus & Memory
Ability to sustain and direct focus.
Improve memory
Focus & Memory
Ability to encode, store, and retrieve information.
Improve mental clarity
Focus & Memory
Sharpness and clearness of thought.
Improve processing speed
Focus & Memory
Speed of performing cognitive tasks.
Improve reaction time
Focus & Memory
Speed of physical or cognitive response to a stimulus.
Improve vitamin B12 status
Focus & Memory
Biochemical sufficiency of cobalamin.
Reduce behavioral symptoms
Focus & Memory
Undesired behavioral disturbances such as agitation or impulsivity.
Reduce brain fog
Focus & Memory
Subjective cognitive slowing or reduced mental clarity.
Reduce dizziness
Focus & Memory
Feeling lightheaded or unsteady.
Reduce headaches
Focus & Memory
Frequency or intensity of headaches.
Reduce migraines
Focus & Memory
Frequency, duration, or intensity of migraine episodes.
Reduce neurodegenerative symptoms
Focus & Memory
Clinical impact of progressive neurologic decline.
Reduce neurologic side effects
Focus & Memory
Undesired neurologic reaction such as seizure, paresthesia, or headache worsening.
Reduce neuropathy symptoms
Focus & Memory
Pain, numbness, or dysfunction due to peripheral nerve problems.
Reduce tingling and numbness
Focus & Memory
Abnormal sensations such as tingling or pins-and-needles.
Reduce tremor
Focus & Memory
Involuntary rhythmic shaking movement.
Reduce withdrawal symptoms
Focus & Memory
Symptoms occurring after reduction or cessation of use.
Weight & Appetite
7Manage your weight and curb cravings.
Increase fat oxidation
Weight & Appetite
Use of fat as an energy source.
Increase resting metabolism
Weight & Appetite
Calories burned at rest; marker of basal metabolism.
Increase satiety
Weight & Appetite
Sense of fullness after eating.
Reduce body fat percentage
Weight & Appetite
Proportion of body weight composed of fat.
Reduce visceral fat
Weight & Appetite
Deep abdominal fat associated with cardiometabolic risk.
Regulate appetite
Weight & Appetite
Desire to eat; may be clinically favorable or unfavorable depending on context.
Support healthy body weight
Weight & Appetite
Total body mass measured over time.
Bones & Joints
18Support strong bones and flexible joints.
Improve bone turnover markers
Bones & Joints
Biochemical indicators of bone formation and resorption.
Improve calcium status
Bones & Joints
Adequacy of calcium availability or stores.
Improve joint function
Bones & Joints
Ability of joints to move and support normal activity.
Improve range of motion
Bones & Joints
Extent of achievable joint movement.
Increase bone density
Bones & Joints
Measure of bone strength and mineralization.
Increase muscle mass
Bones & Joints
Quantity of skeletal muscle tissue.
Increase muscle strength
Bones & Joints
Ability of muscles to generate force.
Increase skeletal muscle mass
Bones & Joints
Amount of muscle tissue relevant to strength and metabolism.
Reduce arthritis symptoms
Bones & Joints
Overall symptoms associated with inflammatory or degenerative joint disease.
Reduce back pain
Bones & Joints
Pain localized to the back.
Reduce fall risk
Bones & Joints
Likelihood of falling due to instability or weakness.
Reduce fracture risk
Bones & Joints
Likelihood of bone fracture.
Reduce joint pain
Bones & Joints
Pain arising from joints or periarticular tissues.
Reduce joint stiffness
Bones & Joints
Reduced ease of joint movement, especially after rest.
Reduce muscle cramps
Bones & Joints
Painful involuntary muscle contractions.
Reduce muscle weakness
Bones & Joints
Reduced ability to generate force.
Reduce sarcopenia
Bones & Joints
Presence of low muscle mass and function.
Support fracture healing
Bones & Joints
Speed and quality of bone repair after fracture.
Gut & Digestion
16Improve digestion and gut comfort.
Improve digestive comfort
Gut & Digestion
Subjective ease and comfort of digestion.
Improve stool consistency
Gut & Digestion
Form or texture of stool.
Increase microbiome diversity
Gut & Digestion
Ecologic diversity of gut microbial communities.
Normalize stool frequency
Gut & Digestion
Number of bowel movements over time.
Reduce abdominal pain
Gut & Digestion
Pain arising from the abdomen or digestive tract.
Reduce digestive symptoms
Gut & Digestion
Overall severity of digestive symptoms.
Reduce gas and flatulence
Gut & Digestion
Excess intestinal gas symptoms.
Reduce gastrointestinal infections
Gut & Digestion
Frequency of infectious GI illnesses.
Reduce heartburn
Gut & Digestion
Reflux symptoms causing burning or discomfort.
Reduce IBD activity
Gut & Digestion
Clinical or biochemical activity of IBD.
Reduce indigestion
Gut & Digestion
Upper abdominal discomfort related to digestion.
Reduce intestinal permeability
Gut & Digestion
Barrier integrity and leakiness of the gut lining.
Reduce malabsorption
Gut & Digestion
Impaired absorption of nutrients from the gut.
Reduce nausea
Gut & Digestion
Feeling of sickness or urge to vomit.
Reduce vomiting
Gut & Digestion
Forceful expulsion of stomach contents.
Relieve constipation
Gut & Digestion
Infrequent, difficult, or hard bowel movements.
Skin, Hair & Nails
17Nourish glowing skin and strong hair and nails.
Improve skin barrier function
Skin, Hair & Nails
Protective integrity of the outer skin barrier.
Improve skin elasticity
Skin, Hair & Nails
Ability of skin to stretch and recoil.
Improve skin hydration
Skin, Hair & Nails
Moisture content or hydration of the skin.
Improve wound healing
Skin, Hair & Nails
Speed and quality of tissue repair.
Increase hair growth or density
Skin, Hair & Nails
Increase or preservation of scalp or body hair.
Increase nail strength
Skin, Hair & Nails
Resistance of nails to splitting or breaking.
Reduce acne
Skin, Hair & Nails
Extent or intensity of acne lesions.
Reduce atopic dermatitis symptoms
Skin, Hair & Nails
Itching, rash, and inflammation related to eczema.
Reduce eczema
Skin, Hair & Nails
Overall clinical burden of eczema.
Reduce hair loss
Skin, Hair & Nails
Excess hair loss relative to normal cycling.
Reduce itching
Skin, Hair & Nails
Itching or urge to scratch.
Reduce nail brittleness
Skin, Hair & Nails
Fragility or easy breakage of nails.
Reduce photosensitivity
Skin, Hair & Nails
Abnormal skin sensitivity to sunlight or light exposure.
Reduce psoriasis symptoms
Skin, Hair & Nails
Extent or severity of psoriatic skin disease.
Reduce rash
Skin, Hair & Nails
Visible inflammatory or irritant skin eruption.
Reduce skin aging signs
Skin, Hair & Nails
Visible features such as fine lines, wrinkles, or loss of firmness.
Reduce wrinkles
Skin, Hair & Nails
Degree of visible skin wrinkling.
Heart & Metabolism
35Support a healthy heart, blood sugar, and cholesterol.
Improve circulation
Heart & Metabolism
Blood flow to limbs and peripheral tissues.
Improve endothelial function
Heart & Metabolism
Ability of blood vessels to dilate and respond normally.
Improve essential fatty acid status
Heart & Metabolism
Adequacy of physiologically necessary fatty acids.
Improve glucose tolerance
Heart & Metabolism
Ability to handle a glucose load appropriately.
Improve insulin sensitivity
Heart & Metabolism
Efficiency of tissue response to insulin.
Improve microcirculation
Heart & Metabolism
Perfusion in small vessels and capillary beds.
Improve vascular function
Heart & Metabolism
Overall health and reactivity of the circulatory system.
Increase HDL cholesterol
Heart & Metabolism
High-density lipoprotein cholesterol; higher is often preferred.
Increase nitric oxide availability
Heart & Metabolism
Availability of nitric oxide relevant to vascular function.
Lower after-meal blood sugar
Heart & Metabolism
Blood glucose after meals.
Lower apolipoprotein B
Heart & Metabolism
Particle-related marker of atherogenic lipoproteins.
Lower blood pressure
Heart & Metabolism
Arterial pressure; direction of benefit depends on baseline status.
Lower fasting blood sugar
Heart & Metabolism
Blood glucose after fasting.
Lower fasting insulin
Heart & Metabolism
Baseline insulin concentration.
Lower HbA1c
Heart & Metabolism
Average blood glucose marker over prior months.
Lower homocysteine
Heart & Metabolism
Amino acid marker linked with vascular and methylation status.
Lower LDL cholesterol
Heart & Metabolism
Low-density lipoprotein cholesterol; lower is often preferred.
Lower lipoprotein(a)
Heart & Metabolism
Inherited lipid-related cardiovascular risk marker.
Lower resting heart rate
Heart & Metabolism
Baseline heart rate measured at rest.
Lower total cholesterol
Heart & Metabolism
Total circulating cholesterol concentration.
Lower triglycerides
Heart & Metabolism
Circulating triglyceride concentration.
Lower uric acid
Heart & Metabolism
Purine metabolism marker associated with gout and cardiometabolic risk.
Reduce advanced glycation end products
Heart & Metabolism
Markers of glycation-related tissue damage.
Reduce angina symptoms
Heart & Metabolism
Chest discomfort due to reduced cardiac blood flow.
Reduce arrhythmias
Heart & Metabolism
Abnormal heart rhythm episodes.
Reduce arterial stiffness
Heart & Metabolism
Reduced elasticity of arteries associated with cardiovascular risk.
Reduce cardiovascular side effects
Heart & Metabolism
Undesired cardiac or vascular side effect.
Reduce edema
Heart & Metabolism
Swelling due to excess fluid accumulation.
Reduce heart attack risk
Heart & Metabolism
Heart attack or acute coronary event.
Reduce hypoglycemia episodes
Heart & Metabolism
Abnormally low blood glucose with symptoms or risk.
Reduce insulin resistance
Heart & Metabolism
Reduced response to insulin associated with metabolic disease.
Reduce major cardiovascular events
Heart & Metabolism
Composite of serious cardiac outcomes such as heart attack, stroke, or death.
Reduce palpitations
Heart & Metabolism
Awareness of irregular, rapid, or forceful heartbeat.
Reduce stroke risk
Heart & Metabolism
Cerebrovascular event causing neurologic injury.
Support healthy platelet function
Heart & Metabolism
Platelet activity relevant to clotting and bleeding.
Performance & Recovery
13Train harder and recover faster.
Improve daily functioning
Performance & Recovery
Capacity to complete routine self-care activities independently.
Improve endurance
Performance & Recovery
Ability to maintain effort over a prolonged duration.
Improve exercise capacity
Performance & Recovery
Ability to sustain physical activity or exertion.
Improve exercise tolerance
Performance & Recovery
Ability to continue activity without unacceptable symptoms.
Improve physical functioning
Performance & Recovery
Ability to perform physical tasks and daily activities.
Improve strength performance
Performance & Recovery
Maximum or functional force production.
Increase lean body mass
Performance & Recovery
Non-fat body mass, often used as a marker of preserved musculature.
Increase power output
Performance & Recovery
Ability to generate force rapidly.
Increase VO2 max
Performance & Recovery
Maximum oxygen utilization during exercise.
Recover faster after exercise
Performance & Recovery
Return to baseline function after exertion.
Reduce exercise-related muscle damage
Performance & Recovery
Markers such as creatine kinase indicating exercise-related tissue stress.
Reduce muscle soreness after exercise
Performance & Recovery
Post-exercise muscle pain and stiffness.
Reduce perceived exertion
Performance & Recovery
Subjective difficulty of physical effort.
Sexual & Reproductive Health
9Support libido, fertility, and reproductive wellness.
Improve erectile function
Sexual & Reproductive Health
Ability to achieve and maintain an erection.
Improve female fertility
Sexual & Reproductive Health
Ability to conceive through female reproductive capacity.
Improve male fertility
Sexual & Reproductive Health
Ability to achieve conception through male reproductive capacity.
Improve sexual function
Sexual & Reproductive Health
Overall sexual performance and satisfaction.
Improve sperm motility
Sexual & Reproductive Health
Ability of sperm to move effectively.
Increase chances of pregnancy
Sexual & Reproductive Health
Frequency of achieved pregnancies.
Increase libido
Sexual & Reproductive Health
Interest in sexual activity.
Increase sperm count
Sexual & Reproductive Health
Number of sperm in semen.
Support ovulation
Sexual & Reproductive Health
Occurrence and quality of ovulatory cycles.
Longevity & Healthy Aging
3Age well and stay vital longer.
Improve quality of life
Longevity & Healthy Aging
Overall effect on physical, mental, and social health status.
Improve survival
Longevity & Healthy Aging
Length of survival during follow-up; higher is better.
Reduce risk of death
Longevity & Healthy Aging
Death from any cause; lowest-level hard clinical outcome.
Hormone Balance
10Support balanced hormones and thyroid health.
Improve free T4
Hormone Balance
Circulating active thyroid hormone fraction.
Improve iodine status
Hormone Balance
Biochemical sufficiency of iodine.
Improve menstrual regularity
Hormone Balance
More predictable and regular menstrual cycles.
Improve thyroid function
Hormone Balance
Overall function of the thyroid axis.
Increase free testosterone
Hormone Balance
Biologically active unbound testosterone fraction.
Normalize cortisol
Hormone Balance
Stress-related glucocorticoid hormone level.
Normalize estradiol
Hormone Balance
Principal estrogen hormone concentration.
Normalize TSH
Hormone Balance
Pituitary hormone used to assess thyroid status.
Reduce PCOS symptoms
Hormone Balance
Clinical burden of polycystic ovary syndrome symptoms.
Support healthy testosterone
Hormone Balance
Primary androgen hormone concentration.
Inflammation & Antioxidants
5Calm inflammation and fight oxidative stress.
Increase antioxidant capacity
Inflammation & Antioxidants
Measured ability to counter oxidative stress.
Lower C-reactive protein
Inflammation & Antioxidants
Acute-phase inflammatory marker.
Reduce inflammation
Inflammation & Antioxidants
Laboratory measures of systemic or local inflammation.
Reduce oxidative stress
Inflammation & Antioxidants
Laboratory indicators of oxidative damage or redox imbalance.
Reduce swelling and inflammation
Inflammation & Antioxidants
Visible or symptomatic tissue inflammation.
Liver & Detox
2Support your liver and natural detox.
Allergy & Histamine
4Ease allergies and histamine reactions.
Reduce allergic reactions
Allergy & Histamine
Immune-mediated adverse reaction of varying severity.
Reduce allergic rhinitis symptoms
Allergy & Histamine
Nasal and eye symptoms related to seasonal or environmental allergy.
Reduce allergy symptoms
Allergy & Histamine
Overall burden of allergic symptoms.
Reduce food sensitivity symptoms
Allergy & Histamine
Symptoms triggered by food-related immune reactions.
Breathing & Lungs
5Support clear airways and healthy lungs.
Improve asthma control
Breathing & Lungs
Degree to which asthma symptoms and exacerbations are minimized.
Reduce cough
Breathing & Lungs
Frequency or intensity of coughing.
Reduce respiratory symptoms
Breathing & Lungs
Overall severity of breathing-related symptoms.
Reduce sinus symptoms
Breathing & Lungs
Pressure, congestion, or pain related to sinus inflammation.
Shorten respiratory infections
Breathing & Lungs
Length of respiratory infection episodes.
Vision & Hearing
8Protect your eyes, ears, and balance.
Improve contrast sensitivity
Vision & Hearing
Ability to distinguish shades or low-contrast details.
Improve night vision
Vision & Hearing
Ability to see or adapt under low-light conditions.
Improve visual acuity
Vision & Hearing
Clarity or sharpness of vision.
Increase macular pigment density
Vision & Hearing
Retinal pigment measure sometimes used in lutein/zeaxanthin studies.
Reduce balance disorder symptoms
Vision & Hearing
Symptoms of disequilibrium related to vestibular dysfunction.
Reduce dry eye symptoms
Vision & Hearing
Irritation, burning, or dryness of the eyes.
Reduce tinnitus
Vision & Hearing
Loudness, distress, or impact of ringing in the ears.
Reduce vertigo
Vision & Hearing
False sensation of spinning or motion.
Women's Health
7Support every stage of women's health.
Improve lactation
Women's Health
Sufficient breast milk production or breastfeeding success.
Normalize menstrual bleeding
Women's Health
Amount of menstrual blood loss.
Reduce hot flashes
Women's Health
Episodes of sudden heat sensation commonly related to menopause.
Reduce menopause symptoms
Women's Health
Burden of symptoms such as hot flashes and sleep disturbance.
Reduce menstrual cramps
Women's Health
Painful menstruation.
Reduce PMS symptoms
Women's Health
Burden of PMS-related mood or physical symptoms.
Reduce pregnancy complications
Women's Health
Adverse maternal or fetal events during pregnancy.
Fill Nutrient Gaps
22Correct deficiencies and fill nutritional gaps.
Correct nutrient deficiency
Fill Nutrient Gaps
Resolution of a documented vitamin, mineral, or nutrient deficiency.
Improve biotin status
Fill Nutrient Gaps
Biochemical sufficiency of biotin.
Improve choline status
Fill Nutrient Gaps
Adequacy of choline availability.
Improve copper status
Fill Nutrient Gaps
Biochemical sufficiency of copper.
Improve folate status
Fill Nutrient Gaps
Biochemical sufficiency of folate.
Improve magnesium status
Fill Nutrient Gaps
Biochemical sufficiency of magnesium.
Improve niacin status
Fill Nutrient Gaps
Biochemical sufficiency of vitamin B3.
Improve nutritional status
Fill Nutrient Gaps
Overall adequacy of nutrient intake and body nutrient reserves.
Improve phosphate status
Fill Nutrient Gaps
Biochemical phosphate balance.
Improve potassium status
Fill Nutrient Gaps
Body potassium balance.
Improve protein status
Fill Nutrient Gaps
Adequacy of protein nutrition and body protein reserves.
Improve riboflavin status
Fill Nutrient Gaps
Biochemical sufficiency of vitamin B2.
Improve selenium status
Fill Nutrient Gaps
Biochemical sufficiency of selenium.
Improve thiamine status
Fill Nutrient Gaps
Biochemical sufficiency of vitamin B1.
Improve vitamin A status
Fill Nutrient Gaps
Biochemical sufficiency of retinoids or carotenoid-derived vitamin A.
Improve vitamin B6 status
Fill Nutrient Gaps
Biochemical sufficiency of pyridoxine-related compounds.
Improve vitamin C status
Fill Nutrient Gaps
Biochemical sufficiency of ascorbic acid.
Improve vitamin D status
Fill Nutrient Gaps
Biochemical sufficiency of vitamin D.
Improve vitamin E status
Fill Nutrient Gaps
Biochemical sufficiency of tocopherols/tocotrienols.
Improve vitamin K status
Fill Nutrient Gaps
Biochemical sufficiency of vitamin K.
Increase omega-3 index
Fill Nutrient Gaps
Red blood cell EPA+DHA content reflecting omega-3 status.
Normalize sodium status
Fill Nutrient Gaps
Body sodium balance.
Kidney & Urinary
11Support kidney and urinary tract health.
Improve electrolyte balance
Kidney & Urinary
Physiologic balance of sodium, potassium, and related ions.
Improve hydration
Kidney & Urinary
Adequacy of body water and fluid balance.
Improve kidney function
Kidney & Urinary
Overall renal filtration and excretory performance.
Improve urine ph
Kidney & Urinary
Acidity or alkalinity of urine.
Lower serum creatinine
Kidney & Urinary
Blood marker commonly used to estimate kidney function.
Reduce albuminuria
Kidney & Urinary
Protein leakage into urine indicating kidney damage risk.
Reduce fluid retention
Kidney & Urinary
Abnormal accumulation of fluid in tissues.
Reduce kidney stone risk
Kidney & Urinary
Likelihood of nephrolithiasis formation or recurrence.
Reduce nighttime urination
Kidney & Urinary
Waking at night to urinate.
Reduce urinary frequency
Kidney & Urinary
Needing to urinate more often than normal.
Reduce urinary symptoms
Kidney & Urinary
Symptoms involving urination or bladder discomfort.
Teeth & Gums
3Support healthy teeth and gums.
Improve oral health
Teeth & Gums
Overall condition of the mouth, teeth, and gums.
Reduce gum inflammation and bleeding
Teeth & Gums
Gum irritation, swelling, or bleeding.
Reduce mouth ulcers
Teeth & Gums
Occurrence of aphthous or other oral ulcers.
Blood & Iron
9Support healthy blood and iron levels.
Improve ferritin
Blood & Iron
Marker of iron stores.
Improve iron status
Blood & Iron
Overall iron sufficiency and availability.
Increase hemoglobin
Blood & Iron
Blood oxygen-carrying protein concentration.
Increase red blood cell count
Blood & Iron
Number of circulating red blood cells.
Normalize mean corpuscular volume
Blood & Iron
Average red blood cell size.
Reduce anemia
Blood & Iron
Presence of clinically meaningful low red cell mass or hemoglobin.
Reduce bleeding tendency
Blood & Iron
Excess susceptibility to bruising or bleeding.
Reduce clotting events
Blood & Iron
Clinically significant pathologic clot formation.
Support healthy coagulation balance
Blood & Iron
Overall blood clotting tendency.
Liver & Digestive Organs
6Support your liver, gallbladder, and pancreas.
Lower ALT
Liver & Digestive Organs
Liver enzyme used to assess hepatocellular injury.
Lower AST
Liver & Digestive Organs
Enzyme used to assess liver and muscle injury.
Normalize alkaline phosphatase
Liver & Digestive Organs
Enzyme related to bile ducts, bone, and liver.
Reduce cholestasis
Liver & Digestive Organs
Impaired bile flow or bile obstruction.
Reduce liver fat
Liver & Digestive Organs
Excess fat accumulation in the liver.
Reduce liver injury risk
Liver & Digestive Organs
Clinically important harmful effect on the liver.
Overall Vitality
3Support overall wellbeing and daily function.
Improve overall well-being
Overall Vitality
Broad self-reported sense of wellness or feeling better.
Reduce pain
Overall Vitality
Severity of pain regardless of body site.
Slow disease progression
Overall Vitality
Clinical worsening or advancement of an underlying condition.
Vision & Hearing (Basic)
3Support healthy vision and hearing.
Reduce eye strain
Vision & Hearing (Basic)
Visual fatigue or discomfort from eye use.
Slow cataract progression
Vision & Hearing (Basic)
Worsening of lens opacity over time.
Slow macular degeneration progression
Vision & Hearing (Basic)
Worsening retinal degeneration affecting central vision.
Cancer Support
3Complementary nutrition during cancer care.
Reduce cancer risk
Cancer Support
Occurrence of new cancer diagnoses.
Slow precancerous lesion progression
Cancer Support
Worsening or advancement of premalignant lesions.
Slow tumor progression
Cancer Support
Growth or spread of benign or malignant neoplastic disease.
Safety & Side Effects
9Info on safety and side effects.
Improve tolerability
Safety & Side Effects
Overall ability to continue the intervention without unacceptable side effects.
Reduce bleeding side effects
Safety & Side Effects
Clinically relevant bleeding related to use or interaction.
Reduce contamination-related harm
Safety & Side Effects
Adverse effect caused by contamination, adulteration, or impurities.
Reduce drowsiness
Safety & Side Effects
Undesired sleepiness or reduced alertness.
Reduce gastrointestinal side effects
Safety & Side Effects
Undesired digestive side effect such as nausea, diarrhea, or pain.
Reduce interaction risk
Safety & Side Effects
Clinically relevant interaction between a supplement and a medication.
Reduce risk of congenital anomalies
Safety & Side Effects
Structural or functional birth defect.
Reduce skin-related side effects
Safety & Side Effects
Undesired skin, rash, or hypersensitivity reaction.
Reduce toxicity risk
Safety & Side Effects
Harm from excessive exposure or poisoning.