Is a higher dose always better?

No. Dose-fit rewards landing inside the range studied for the outcome — over-dosing (common with melatonin) or under-dosing both lower the score. The goal is the effective dose, not the biggest number.

What does the Value score mean?

The Value score compares a product's price per serving with clinically relevant products ranked for the same outcome. A score of 50 is the typical price; above 50 means better value than typical, while below 50 means the product costs more than typical. It is a 0–100 value signal, not a percentile.

Why is the cheapest product not #1?

Cost is only one input. The cheapest pick here is a citrate form with weaker absorption and a stock-risk flag, so it leads on Value-for-cost but trails on the composite that also weighs evidence, dose fit and availability.

Are these affiliate links?

Retailer links may be affiliate links and DoseRank may earn a commission. Rankings and placement are determined by the scoring model only — never by payment from a brand.

Is this medical advice?

No. DoseRank summarizes evidence to help you choose; it is not a substitute for a clinician, especially if you are pregnant, breastfeeding, on medication, or managing a health condition.

Reduce infections

What this outcome means

Infection incidence is how often you come down with infectious illness over a stretch of time, from colds to more serious bugs. On DoseRank it maps to a defined health outcome built from human studies on infection rates, episode frequency, and illness duration – data sourced from open sources and specialized resources. DoseRank is not medical advice.

Who it's for

Catch-everything typesPeople who seem to pick up every bug going around.

High-exposure routinesCrowded commutes, classrooms, or wards that raise day-to-day exposure.

Recurrent infectionsThe same infections returning again and again through the year.

Stack buildersAlready taking supplements such as D-Mannose or Cranberry and want the dose right.

Evidence level

92Strong

D-Mannose and Cranberry – have strong public evidence. DoseRank looks at both evidence quality and formula fit. A DoseFit Score of 74 means this product's ingredient forms and doses are close to what was used in the studies behind this ranking - DoseRank weights each product ingredient.

Best ingredients

D-Mannose and Cranberry are the best supported ingredient signals for this outcome.

Dose partly matchedDoseFit 74

Scores reward products dosed inside or above the studied range, not just the right ingredient. Examples: In range: D-Mannose 1300 mg vs 1000-2000 mg, Cranberry 500 mg vs 300-1000 mg.

Processed

1.2k

Available

1.2k

Ingredients

Brands

192

Coverage

100%

How to read the scores

What every metric means

Each score is 0–100. Higher is better for every metric below.

CompositeThe overall DoseRank score — a weighted blend of clinical strength, evidence, dose fit, trust and value.Higher is better

ClinicalHow strongly the formula's ingredients and doses match what clinical studies used for this outcome.Higher is better

EvidenceHow much published human research backs the formula's key ingredients for this outcome — both how many studies exist and how strong they are.Higher is better

ValueHow the price per serving compares with similar products for this outcome — 50 is the typical price, higher means better value for your money.Higher is better

TrustHow well customers rate this product, with extra weight given to ratings backed by a large number of reviews.Higher is better

PopularityHow strongly this product sells compared with the other ranked products for this outcome.Higher is better

This legend covers the scores on this page — for data sources, scoring weights, and limits, read the full methodology →

Not sure which is right for you?

Answer a few questions about your goals, habits, stack, and budget. Then, DoseRank will find the products that best match your needs based on your answers. It's free and only takes 60 seconds! No account is required.

Take 60-sec quiz

Get a personal report

A saved, shareable breakdown: your matched products, dose math, interaction flags to discuss with a clinician, and a price-tracked stack you can revisit.

Questions

Frequently asked

Each product gets a composite score blending clinical strength, evidence, dose fit, trust and value. The #1 on the DoseRank tab has the highest composite; the other tabs re-rank the same products by Value, Trust, or Popularity. Placement is never paid.

Reduce infections

What this outcome means

Who it's for

Catch-everything typesPeople who seem to pick up every bug going around.

High-exposure routinesCrowded commutes, classrooms, or wards that raise day-to-day exposure.

Recurrent infectionsThe same infections returning again and again through the year.

Stack buildersAlready taking supplements such as D-Mannose or Cranberry and want the dose right.

Evidence level

92Strong

Best ingredients

D-Mannose and Cranberry are the best supported ingredient signals for this outcome.

Dose partly matchedDoseFit 74

Scores reward products dosed inside or above the studied range, not just the right ingredient. Examples: In range: D-Mannose 1300 mg vs 1000-2000 mg, Cranberry 500 mg vs 300-1000 mg.

Processed

1.2k

Available

1.2k

Ingredients

Brands

192

Coverage

100%

Relevant ingredients

Which ingredient types matter for infection incidenceOpen to see which ingredient types matter for infection incidence

346 products across 3 ingredient types — open to filter the ranking.

Use types to filter ranked products

Sweeteners & Functional Sugars

90 products

Sugars and sugar-like compounds that sweeten or feed gut microbes. Ranges from table sugar to functional prebiotic sugars with little blood-sugar impact.

Typical:

Botanicals/Herbal Extracts

255 products

Concentrated plant and herbal extracts standardized to actives. Potency depends on the extract ratio and marker content, not raw weight.

Typical:

Probiotics & Microorganisms

1 product

Live beneficial bacteria and yeasts measured in CFUs. Strain identity and viability at expiry matter far more than headline colony counts.

Typical:

Top decision cards

Best products for infection incidence

Ranking by · Composite outcome score

Best overall — the composite outcome score.

Top pick · DoseRank

Why this ranks #1 for infection incidence

Nutricost, Women, D-Mannose with Cranberry Extract, 180 Capsules

Nutricost$0.33 / serving4.8 · 560Available now

Also helps with

Urinary tract symptoms

Endothelial function

Antioxidant capacity

Why this ranks here

Evidence fitD-Mannose and Cranberry are the strongest evidence signals for this outcome.
Dose fit2 of 2 dosed ingredients land in the studied range. D-Mannose at 1300 mg lands inside the studied 1000-2000 mg window.
Price / serving$0.33 per serving — high price tier for this outcome.
AvailabilityIn stock across major retailers; 99% availability confidence.
TrustSolid trust signals from buyer ratings, with room to grow.

The numbers

1300 mgIn rangeinside the studied 1000-2000 mg window

500 mgIn rangeinside the studied 300-1000 mg window

Compare top 3 Product data Open at retailer

The rest of the ranking · DoseRank

Top 10 ranked products

Solaray, CranActin® D-Mannose, 120 VegCaps

SolarayClinical89Dose fit68Popularity76$0.78/ serving

Solaray, CranActin® D-Mannose, 60 VegCaps

SolarayClinical89Dose fit68Popularity76$0.86/ serving

Zhou Nutrition, Cran-Defense™, 60 Veggie Capsules

Zhou NutritionClinical89Dose fit68Popularity30$0.54/ serving

NOW Foods, Mannose Cranberry, 90 Veg Capsules

NOW FoodsClinical83Dose fit57Popularity98$0.39/ serving

Solaray, CranActin®, D-Mannose Powder, 8 oz (226 g)

SolarayClinical91Dose fit83Popularity30$1.32/ serving

Nature's Answer, UT Answer®, D-Mannose & Cranberry Concentrate, 4 fl oz (120 ml)

Nature's AnswerClinical91Dose fit86Popularity76$3.12/ serving

The Vitamin Shoppe, Cranberry With D-Mannose, 120 Vegetable Capsules

The Vitamin ShoppeClinical89Dose fit68Popularity30$0.70/ serving

NOW Foods, Certified Organic D-Mannose Pure Powder, 6 oz (170 g)

NOW FoodsClinical83Dose fit90Popularity84$0.36/ serving

The Vitamin Shoppe, Cranberry With D-Mannose, 60 Vegetable Capsules

The Vitamin ShoppeClinical89Dose fit68Popularity30$0.87/ serving