Is a higher dose always better?

No. Dose-fit rewards landing inside the range studied for the outcome — over-dosing (common with melatonin) or under-dosing both lower the score. The goal is the effective dose, not the biggest number.

What does the Value score mean?

The Value score compares a product's price per serving with clinically relevant products ranked for the same outcome. A score of 50 is the typical price; above 50 means better value than typical, while below 50 means the product costs more than typical. It is a 0–100 value signal, not a percentile.

Why is the cheapest product not #1?

Cost is only one input. The cheapest pick here is a citrate form with weaker absorption and a stock-risk flag, so it leads on Value-for-cost but trails on the composite that also weighs evidence, dose fit and availability.

Are these affiliate links?

Retailer links may be affiliate links and DoseRank may earn a commission. Rankings and placement are determined by the scoring model only — never by payment from a brand.

Is this medical advice?

No. DoseRank summarizes evidence to help you choose; it is not a substitute for a clinician, especially if you are pregnant, breastfeeding, on medication, or managing a health condition.

Improve tolerability

What this outcome means

Tolerability is how comfortably you can stay on a regimen over time without side effects becoming too much to bear. On DoseRank it maps to a defined health outcome built from human studies on side-effect frequency, dropout and discontinuation rates, and patient-reported comfort scores – data sourced from open sources and specialized resources. DoseRank is not medical advice.

Who it's for

Sensitive stomachsPeople prone to nausea or cramping from new routines.

On a long regimenThose needing to stay consistent for months without disruption.

Past dropoutsAnyone who quit before because side effects got uncomfortable.

Stack buildersAlready taking supplements such as Magnesium Bisglycinate and want the dose right.

Evidence level

78Moderate-strong

Magnesium Bisglycinate – has moderate public evidence for this outcome. This usually means there are smaller or mechanistic studies, but not randomized human trials. A DoseFit Score of 71 means this product's ingredient forms and doses are close to what was used in the studies behind this ranking - DoseRank weights each product ingredient.

Best available ingredients

Magnesium Bisglycinate is the best supported ingredient signal for this outcome.

Dose partly matchedDoseFit 71

Scores reward products dosed inside or above the studied range, not just the right ingredient. Examples: In range: Magnesium Bisglycinate 300 mg vs 200-800 mg.

Processed

788

Available

788

Ingredients

Brands

150

Coverage

100%

How to read the scores

What every metric means

Each score is 0–100. Higher is better for every metric below.

CompositeThe overall DoseRank score — a weighted blend of clinical strength, evidence, dose fit, trust and value.Higher is better

ClinicalHow strongly the formula's ingredients and doses match what clinical studies used for this outcome.Higher is better

EvidenceHow much published human research backs the formula's key ingredients for this outcome — both how many studies exist and how strong they are.Higher is better

ValueHow the price per serving compares with similar products for this outcome — 50 is the typical price, higher means better value for your money.Higher is better

TrustHow well customers rate this product, with extra weight given to ratings backed by a large number of reviews.Higher is better

PopularityHow strongly this product sells compared with the other ranked products for this outcome.Higher is better

This legend covers the scores on this page — for data sources, scoring weights, and limits, read the full methodology →

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Get a personal report

A saved, shareable breakdown: your matched products, dose math, interaction flags to discuss with a clinician, and a price-tracked stack you can revisit.

Questions

Frequently asked

Each product gets a composite score blending clinical strength, evidence, dose fit, trust and value. The #1 on the DoseRank tab has the highest composite; the other tabs re-rank the same products by Value, Trust, or Popularity. Placement is never paid.

Improve tolerability

What this outcome means

Who it's for

Sensitive stomachsPeople prone to nausea or cramping from new routines.

On a long regimenThose needing to stay consistent for months without disruption.

Past dropoutsAnyone who quit before because side effects got uncomfortable.

Stack buildersAlready taking supplements such as Magnesium Bisglycinate and want the dose right.

Evidence level

78Moderate-strong

Best available ingredients

Magnesium Bisglycinate is the best supported ingredient signal for this outcome.

Dose partly matchedDoseFit 71

Scores reward products dosed inside or above the studied range, not just the right ingredient. Examples: In range: Magnesium Bisglycinate 300 mg vs 200-800 mg.

Processed

788

Available

788

Ingredients

Brands

150

Coverage

100%

Relevant ingredients

Which ingredient types matter for tolerabilityOpen to see which ingredient types matter for tolerability

746 products across 2 ingredient types — open to filter the ranking.

Use types to filter ranked products

Vitamins

32 products

Essential micronutrients the body can't make in sufficient amounts. Fat-soluble ones (A, D, E, K) store up; water-soluble ones need regular topping-up.

Typical:

Minerals & Trace Elements

714 products

Inorganic nutrients from calcium to zinc. The chemical form drives absorption – chelates and citrates usually beat cheap oxides.

Typical: , ,

Top decision cards

Best products for tolerability

Ranking by · Composite outcome score

Best overall — the composite outcome score.

Top pick · DoseRank

Why this ranks #1 for tolerability

NOW Foods, Magnesium Bisglycinate Powder, 8 oz (227 g)

NOW Foods$0.18 / serving4.5 · 10,540Available now

Also helps with

Magnesium status

Muscle cramps

Sleep quality

Why this ranks here

Evidence fitMagnesium Bisglycinate has moderate human evidence for this outcome.
Dose fitMagnesium Bisglycinate at 300 mg lands inside the studied 200-800 mg window.
Price / serving$0.18 per serving — mid price tier for this outcome.
AvailabilityIn stock across major retailers; 99% availability confidence.
TrustStrong trust signals — consistently high marks from verified buyer ratings.

The numbers

300 mgIn rangeinside the studied 200-800 mg window

Compare top 3 Product data Open at retailer

The rest of the ranking · DoseRank

Top 10 ranked products

Nutricost, Magnesium Glycinate, Unflavored , 8.9 oz (250 g)

NutricostClinical87Dose fit67Popularity96$0.13/ serving

NOW Foods, Magnesium Glycinate With BioPerine®, 180 Veg Capsules

NOW FoodsClinical87Dose fit67Popularity99$0.19/ serving

KAL, Chelated Magnesium Bisglycinate, 180 Tablets (105 mg per Tablet)

KALClinical87Dose fit71Popularity98$0.25/ serving

NOW Foods, Magnesium Glycinate, 180 Tablets (100 mg per Tablet)

NOW FoodsClinical87Dose fit67Popularity100$0.21/ serving

21st Century, Chelated Magnesium Glycinate, 90 Capsules, (100 mg per Capsule)

21st CenturyClinical87Dose fit67Popularity96$0.23/ serving

Country Life, Chelated Magnesium Glycinate, 180 Tablets (133 mg per Tablet)

Country LifeClinical88Dose fit74Popularity91$0.45/ serving

Country Life, Chelated Magnesium Glycinate, 400 mg, 180 Tablets (133 mg per Tablet)

Country LifeClinical88Dose fit74Popularity91$0.45/ serving

Qunol, Magnesium, 120 Capsules (210 mg per Capsule)

QunolClinical88Dose fit75Popularity76$0.23/ serving

Solaray, High Absorption Magnesium Glycinate, 240 VegCaps

SolarayClinical87Dose fit73Popularity99$0.48/ serving