Is a higher dose always better?

No. Dose-fit rewards landing inside the range studied for the outcome — over-dosing (common with melatonin) or under-dosing both lower the score. The goal is the effective dose, not the biggest number.

What does the Value score mean?

The Value score compares a product's price per serving with clinically relevant products ranked for the same outcome. A score of 50 is the typical price; above 50 means better value than typical, while below 50 means the product costs more than typical. It is a 0–100 value signal, not a percentile.

Why is the cheapest product not #1?

Cost is only one input. The cheapest pick here is a citrate form with weaker absorption and a stock-risk flag, so it leads on Value-for-cost but trails on the composite that also weighs evidence, dose fit and availability.

Are these affiliate links?

Retailer links may be affiliate links and DoseRank may earn a commission. Rankings and placement are determined by the scoring model only — never by payment from a brand.

Is this medical advice?

No. DoseRank summarizes evidence to help you choose; it is not a substitute for a clinician, especially if you are pregnant, breastfeeding, on medication, or managing a health condition.

Lower ALT

What this outcome means

Alanine aminotransferase, or ALT, is a liver enzyme that shows up in your bloodwork and signals how much strain or injury your liver cells are under. On DoseRank it maps to a defined health outcome built from human studies on serum ALT levels, hepatocellular injury markers, and enzyme normalization – data sourced from open sources and specialized resources. DoseRank is not medical advice.

Who it's for

Elevated liver labsBloodwork showing higher-than-normal ALT on a recent panel.

Fatty liver concernsMetabolic strain putting extra load on liver cells.

Routine lab watchersPeople tracking liver enzymes as part of regular checkups.

Stack buildersAlready taking supplements such as d-Alpha Tocopherol and want the dose right.

Evidence level

90Strong

d-Alpha Tocopherol – has strong public evidence. DoseRank looks at both evidence quality and formula fit. A DoseFit Score of 91 means this product's ingredient forms and doses are close to what was used in the studies behind this ranking - DoseRank weights each product ingredient.

Best ingredients

d-Alpha Tocopherol is the best supported ingredient signal for this outcome.

Dose matchedDoseFit 91

Scores reward products dosed inside or above the studied range, not just the right ingredient. Examples: Above range: d-Alpha Tocopherol 670 mg vs 268-536 mg.

Processed

2.2k

Available

2.2k

Ingredients

Brands

283

Coverage

100%

How to read the scores

What every metric means

Each score is 0–100. Higher is better for every metric below.

CompositeThe overall DoseRank score — a weighted blend of clinical strength, evidence, dose fit, trust and value.Higher is better

ClinicalHow strongly the formula's ingredients and doses match what clinical studies used for this outcome.Higher is better

EvidenceHow much published human research backs the formula's key ingredients for this outcome — both how many studies exist and how strong they are.Higher is better

ValueHow the price per serving compares with similar products for this outcome — 50 is the typical price, higher means better value for your money.Higher is better

TrustHow well customers rate this product, with extra weight given to ratings backed by a large number of reviews.Higher is better

PopularityHow strongly this product sells compared with the other ranked products for this outcome.Higher is better

This legend covers the scores on this page — for data sources, scoring weights, and limits, read the full methodology →

Not sure which is right for you?

Answer a few questions about your goals, habits, stack, and budget. Then, DoseRank will find the products that best match your needs based on your answers. It's free and only takes 60 seconds! No account is required.

Take 60-sec quiz

Get a personal report

A saved, shareable breakdown: your matched products, dose math, interaction flags to discuss with a clinician, and a price-tracked stack you can revisit.

Questions

Frequently asked

Each product gets a composite score blending clinical strength, evidence, dose fit, trust and value. The #1 on the DoseRank tab has the highest composite; the other tabs re-rank the same products by Value, Trust, or Popularity. Placement is never paid.

Lower ALT

What this outcome means

Who it's for

Elevated liver labsBloodwork showing higher-than-normal ALT on a recent panel.

Fatty liver concernsMetabolic strain putting extra load on liver cells.

Routine lab watchersPeople tracking liver enzymes as part of regular checkups.

Stack buildersAlready taking supplements such as d-Alpha Tocopherol and want the dose right.

Evidence level

90Strong

Best ingredients

d-Alpha Tocopherol is the best supported ingredient signal for this outcome.

Dose matchedDoseFit 91

Scores reward products dosed inside or above the studied range, not just the right ingredient. Examples: Above range: d-Alpha Tocopherol 670 mg vs 268-536 mg.

Processed

2.2k

Available

2.2k

Ingredients

Brands

283

Coverage

100%

Relevant ingredients

Which ingredient types matter for alanine aminotransferase (alt)Open to see which ingredient types matter for alanine aminotransferase (alt)

1.6k products across 4 ingredient types — open to filter the ranking.

Use types to filter ranked products

Botanicals/Herbal Extracts

412 products

Concentrated plant and herbal extracts standardized to actives. Potency depends on the extract ratio and marker content, not raw weight.

Typical: , ,

Antioxidants & Bioactive Compounds

101 products

Molecules that neutralize free radicals and tune cell signaling. Helpful in balance; mega-doses can blunt the body's own adaptive defenses.

Typical: ,

Vitamins

996 products

Essential micronutrients the body can't make in sufficient amounts. Fat-soluble ones (A, D, E, K) store up; water-soluble ones need regular topping-up.

Typical: ,

Fatty Acids & Lipids

82 products

Dietary fats including omega-3s and structural lipids. Look at the active EPA/DHA amounts and freshness, since oils oxidize and turn rancid.

Typical:

Top decision cards

Best products for alanine aminotransferase (alt)

Ranking by · Composite outcome score

Best overall — the composite outcome score.

Top pick · DoseRank

Why this ranks #1 for alanine aminotransferase (alt)

Solgar, Vitamin E, 100 Softgels

Solgar$0.23 / serving4.8 · 2,515Available now

Also helps with

Vitamin E status

Hepatic steatosis

Antioxidant capacity

Why this ranks here

Evidence fitd-Alpha Tocopherol is the strongest evidence signal for this outcome.
Dose fitd-Alpha Tocopherol at 670 mg is higher than the studied 268-536 mg window.
Price / serving$0.23 per serving — mid price tier for this outcome.
AvailabilityIn stock across major retailers; 99% availability confidence.
TrustStrong trust signals — consistently high marks from verified buyer ratings.

The numbers

670 mgAbove rangehigher than the studied 268-536 mg window

64 mg

Compare top 3 Product data Open at retailer

The rest of the ranking · DoseRank

Top 10 ranked products

NOW Foods, E-400 with Mixed Tocopherols, 268 mg (400 IU), 250 Softgels

NOW FoodsClinical87Dose fit67Popularity91$0.11/ serving

Solgar, Vitamin E, Naturally Sourced, 100 Softgels

SolgarClinical87Dose fit67Popularity91$0.12/ serving

Solgar, Vitamin E, 268 mg (400 IU), 100 Softgels

SolgarClinical87Dose fit67Popularity89$0.12/ serving

Solgar, Vitamin E, Naturally Sourced, 268 mg (400 IU), 250 Softgels

SolgarClinical87Dose fit67Popularity84$0.10/ serving

NOW Foods, E-400, 268 mg (400 IU), 50 Softgels

NOW FoodsClinical87Dose fit67Popularity91$0.14/ serving

NOW Foods, Milk Thistle Extract, 300 mg, 200 Veg Capsules

NOW FoodsClinical86Dose fit71Popularity99$0.12/ serving

Revive, Liver, 120 Vegetarian Capsules

ReviveClinical96Dose fit79Popularity76$1.65/ serving

NOW Foods, Milk Thistle Extract, 750 mg, 90 Veg Capsules

NOW FoodsClinical88Dose fit86Popularity98$0.26/ serving

California Gold Nutrition, Sunflower Vitamin E with Mixed Tocopherols, 400 IU, 90 Veggie Softgels

California Gold NutritionClinical87Dose fit67Popularity91$0.20/ serving