DOSERANKEVIDENCE-BASED SUPPLEMENTS
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DOSERANKEVIDENCE-BASED SUPPLEMENTS
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  2. ·Outcomes
  3. ·Muscle health
  4. ·Muscle weakness

Reduce muscle weakness

View top productsTake the 60-sec quizGet the reportSee methodology

What this outcome means

Muscle weakness is when your muscles can't produce the force they should, leaving everyday lifting and movement harder than it once was. On DoseRank it maps to a defined health outcome built from human studies on grip strength, force output, and physical performance measures – data sourced from open sources and specialized resources. DoseRank is not medical advice.

Who it's for

Losing strengthEveryday lifting and carrying that now feels heavier.
Age-related declineMuscle and power fading gradually through later decades.
Recovery and disuseStrength lost after illness, bed rest, or immobilization.
Stack buildersAlready taking supplements such as Vitamin D or Phosphorus and want the dose right.

Evidence level

78Moderate-strong

Vitamin D and Phosphorus – have moderate public evidence for this outcome. This usually means there are smaller or mechanistic studies, but not randomized human trials. A DoseFit Score of 90 means this product's ingredient forms and doses are close to what was used in the studies behind this ranking - DoseRank weights each product ingredient.

Best available ingredients

Vitamin D and Phosphorus are the best supported ingredient signals for this outcome.

Dose matchedDoseFit 90

Scores reward products dosed inside or above the studied range, not just the right ingredient. Examples: In range: Vitamin D 5000 IU vs 1000-5000 IU; Below range: Phosphorus 85 mg vs 500-1000 mg.

ProcessedProcessedEvery product DoseRank ingested and scored for this outcome, before any availability or relevance filtering.
2.4k
AvailableAvailableOf the products processed, how many are currently in stock and purchasable from a tracked retailer.
2.4k
IngredientsIngredientsNumber of relevant ingredients for this outcome. Each is judged on its own evidence and dose fit score.
6
BrandsBrandsNumber of unique brands represented across the ranked products for this outcome.
332
CoverageCoverageHigher is betterShare of the relevant, in-stock market DoseRank has structured data for. Higher coverage means fewer blind spots in the ranking.
100%

How to read the scores

What every metric means

Each score is 0–100. Higher is better for every metric below.
CompositeThe overall DoseRank score — a weighted blend of clinical strength, evidence, dose fit, trust and value.Higher is better
ClinicalHow strongly the formula's ingredients and doses match what clinical studies used for this outcome.Higher is better
EvidenceHow much published human research backs the formula's key ingredients for this outcome — both how many studies exist and how strong they are.Higher is better
ValueHow the price per serving compares with similar products for this outcome — 50 is the typical price, higher means better value for your money.Higher is better
TrustHow well customers rate this product, with extra weight given to ratings backed by a large number of reviews.Higher is better
PopularityHow strongly this product sells compared with the other ranked products for this outcome.Higher is better

This legend covers the scores on this page — for data sources, scoring weights, and limits, read the full methodology →

Not sure which is right for you?

Answer a few questions about your goals, habits, stack, and budget. Then, DoseRank will find the products that best match your needs based on your answers. It's free and only takes 60 seconds! No account is required.

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Get a personal report

A saved, shareable breakdown: your matched products, dose math, interaction flags to discuss with a clinician, and a price-tracked stack you can revisit.

Questions

Frequently asked

Each product gets a composite score blending clinical strength, evidence, dose fit, trust and value. The #1 on the DoseRank tab has the highest composite; the other tabs re-rank the same products by Value, Trust, or Popularity. Placement is never paid.

No. Dose-fit rewards landing inside the range studied for the outcome — over-dosing (common with melatonin) or under-dosing both lower the score. The goal is the effective dose, not the biggest number.

The Value score compares a product's price per serving with clinically relevant products ranked for the same outcome. A score of 50 is the typical price; above 50 means better value than typical, while below 50 means the product costs more than typical. It is a 0–100 value signal, not a percentile.

Cost is only one input. The cheapest pick here is a citrate form with weaker absorption and a stock-risk flag, so it leads on Value-for-cost but trails on the composite that also weighs evidence, dose fit and availability.

Retailer links may be affiliate links and DoseRank may earn a commission. Rankings and placement are determined by the scoring model only — never by payment from a brand.

No. DoseRank summarizes evidence to help you choose; it is not a substitute for a clinician, especially if you are pregnant, breastfeeding, on medication, or managing a health condition.

DoseRank is not medical advice. Scores summarize publicly available product and study data to help you compare options; they are not a diagnosis or a treatment recommendation. If you are pregnant, breastfeeding, taking medication, or managing a health condition, consult a qualified clinician before starting any supplement. Retailer links may be affiliate links and DoseRank may earn a commission — rankings and placement are determined by the scoring model only, never by payment from a brand. Statements about supplements have not been evaluated by the FDA. Products are not intended to diagnose, treat, cure, or prevent any disease.

Relevant ingredients

Which ingredient types matter for muscle weaknessOpen to see which ingredient types matter for muscle weakness

452 products across 1 ingredient types — open to filter the ranking.
Use types to filter ranked products

Vitamins

452 products

Essential micronutrients the body can't make in sufficient amounts. Fat-soluble ones (A, D, E, K) store up; water-soluble ones need regular topping-up.

Typical:

Top decision cards

Best products for muscle weakness

Ranking by · Composite outcome score

Best overall — the composite outcome score.

Top pick · DoseRank

Why this ranks #1 for muscle weakness

#1

Solaray, Vitamin D3 + K2, 60 VegCaps

Solaray$0.31 / serving4.9 · 92,933Available now
Also helps withVitamin K statusImmune functionRespiratory infection incidence

Why this ranks here

  • Evidence fitVitamin D and Phosphorus have moderate human evidence for this outcome.
  • Dose fit1 of 2 dosed ingredients land in the studied range. Vitamin D at 5000 IU lands inside the studied 1000-5000 IU window.
  • Price / serving$0.31 per serving — mid price tier for this outcome.
  • AvailabilityIn stock across major retailers; 99% availability confidence.
  • TrustStrong trust signals — consistently high marks from verified buyer ratings.

The numbers

78
81
90
71

5000 IUIn rangeinside the studied 1000-5000 IU window
85 mgBelow rangebelow the studied 500-1000 mg window

110 mg
50 mcg
Compare top 3Product dataOpen at retailer

The rest of the ranking · DoseRank

Top 10 ranked products
#ProductPrice
2

Solaray, Super Bio Vitamin D-3, 125 mcg, 120 Softgels

Solaray
Clinical81Dose fit90Popularity30$0.12/ serving
3

Solaray, Kids Vitamins & Minerals Chewable, Natural Black Cherry, 60 Chewables

Solaray
Clinical78Dose fit67Popularity76$0.28/ serving
4

Nature's Life, Super D-3, 100 mcg, 100 Softgels

Nature's Life
Clinical80Dose fit84Popularity30$0.12/ serving
5

Nature's Life, Ultra D-3, 250 mcg , 100 Softgels

Nature's Life
Clinical81Dose fit93Popularity30$0.18/ serving
6

LifeTime Vitamins, VitaLiquids, Bone Support, Strawberry, 16 fl oz (473 ml)

LifeTime Vitamins
Clinical78Dose fit67Popularity50$0.50/ serving
7

LifeTime Vitamins, Bone Support, Orange Vanilla, 16 fl oz (473 ml)

LifeTime Vitamins
Clinical78Dose fit67Popularity50$0.50/ serving
8

Solaray, Vitamin D-3 Lozenges, Natural Lemon, 50 mcg, 60 Lozenges

Solaray
Clinical78Dose fit73Popularity30$0.15/ serving
9

Nature's Life, Mighty Mini Vite, Daily Multivitamin, 240 Micro Tablets

Nature's Life
Clinical78Dose fit67Popularity30$0.15/ serving
10

Solaray, Cal-Mag Citrate 2:1 Ratio, 180 Capsules

Solaray
Clinical78Dose fit67Popularity50$0.76/ serving

Keep exploring

Related outcomes

Muscle crampsPainful involuntary muscle contractions.Muscle massQuantity of skeletal muscle tissue.Muscle strengthAbility of muscles to generate force.Sarcopenia statusPresence of low muscle mass and function.
Last updated Aug 20, 2026

DoseRank is not medical advice. Scores summarize publicly available product and study data to help you compare options; they are not a diagnosis or a treatment recommendation. If you are pregnant, breastfeeding, taking medication, or managing a health condition, consult a qualified clinician before starting any supplement. Retailer links may be affiliate links and DoseRank may earn a commission — rankings and placement are determined by the scoring model only, never by payment from a brand. Statements about supplements have not been evaluated by the FDA. Products are not intended to diagnose, treat, cure, or prevent any disease.

Comparison preview

Compare the top 3, side by side

Sign-in to see all metrics

The top three for the current view — free to read, no account. Saving, exporting, alerts and the full filter set unlock once you sign in or build a personal report.

Metric
#1Solaray, Vitamin D3 + K2, 60 VegCapsSolaray · $0.31/serving
#2Solaray, Super Bio Vitamin D-3, 125 mcg, 120 SoftgelsSolaray · $0.12/serving
#3Solaray, Kids Vitamins & Minerals Chewable, Natural Black Cherry, 60 ChewablesSolaray · $0.28/serving
Composite787474
Clinical818178
Dose fit909067
Value718673
Popularity983076
Key dosages & price · raw values
5000 IUHighest5000 IUHighest1000 IU
Rating
Number of ratings
Price
Price per serving
Serving size
Trust

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Unlocks with accountFull list of ingredients and dosagesFull list of metricsPrice-drop alertsRanking-changes alertsPersistent stack