Is a higher dose always better?

No. Dose-fit rewards landing inside the range studied for the outcome — over-dosing (common with melatonin) or under-dosing both lower the score. The goal is the effective dose, not the biggest number.

What does the Value score mean?

The Value score compares a product's price per serving with clinically relevant products ranked for the same outcome. A score of 50 is the typical price; above 50 means better value than typical, while below 50 means the product costs more than typical. It is a 0–100 value signal, not a percentile.

Why is the cheapest product not #1?

Cost is only one input. The cheapest pick here is a citrate form with weaker absorption and a stock-risk flag, so it leads on Value-for-cost but trails on the composite that also weighs evidence, dose fit and availability.

Are these affiliate links?

Retailer links may be affiliate links and DoseRank may earn a commission. Rankings and placement are determined by the scoring model only — never by payment from a brand.

Is this medical advice?

No. DoseRank summarizes evidence to help you choose; it is not a substitute for a clinician, especially if you are pregnant, breastfeeding, on medication, or managing a health condition.

Reduce migraines

What this outcome means

Migraine severity is how often migraines strike, how long they last, and how disabling the pain and symptoms feel. On DoseRank it maps to a defined health outcome built from human studies on attack frequency, episode duration, and pain-intensity scores – data sourced from open sources and specialized resources. DoseRank is not medical advice.

Who it's for

Frequent attacksPeople hit by migraines many days each month.

Long-lasting episodesThose whose attacks stretch on for a day or more.

Aura-prone migrainesPeople who get visual or sensory warnings before the pain begins.

Stack buildersAlready taking supplements such as Riboflavin and want the dose right.

Evidence level

92Strong

Riboflavin – has strong public evidence. DoseRank looks at both evidence quality and formula fit. A DoseFit Score of 90 means this product's ingredient forms and doses are close to what was used in the studies behind this ranking - DoseRank weights each product ingredient.

Best ingredients

Riboflavin is the best supported ingredient signal for this outcome.

Dose matchedDoseFit 90

Scores reward products dosed inside or above the studied range, not just the right ingredient. Examples: In range: Riboflavin 400 mg vs 400-400 mg.

Processed

6.3k

Available

6.3k

Ingredients

Brands

465

Coverage

100%

How to read the scores

What every metric means

Each score is 0–100. Higher is better for every metric below.

CompositeThe overall DoseRank score — a weighted blend of clinical strength, evidence, dose fit, trust and value.Higher is better

ClinicalHow strongly the formula's ingredients and doses match what clinical studies used for this outcome.Higher is better

EvidenceHow much published human research backs the formula's key ingredients for this outcome — both how many studies exist and how strong they are.Higher is better

ValueHow the price per serving compares with similar products for this outcome — 50 is the typical price, higher means better value for your money.Higher is better

TrustHow well customers rate this product, with extra weight given to ratings backed by a large number of reviews.Higher is better

PopularityHow strongly this product sells compared with the other ranked products for this outcome.Higher is better

This legend covers the scores on this page — for data sources, scoring weights, and limits, read the full methodology →

Not sure which is right for you?

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Take 60-sec quiz

Get a personal report

A saved, shareable breakdown: your matched products, dose math, interaction flags to discuss with a clinician, and a price-tracked stack you can revisit.

Questions

Frequently asked

Each product gets a composite score blending clinical strength, evidence, dose fit, trust and value. The #1 on the DoseRank tab has the highest composite; the other tabs re-rank the same products by Value, Trust, or Popularity. Placement is never paid.

Reduce migraines

What this outcome means

Who it's for

Frequent attacksPeople hit by migraines many days each month.

Long-lasting episodesThose whose attacks stretch on for a day or more.

Aura-prone migrainesPeople who get visual or sensory warnings before the pain begins.

Stack buildersAlready taking supplements such as Riboflavin and want the dose right.

Evidence level

92Strong

Best ingredients

Riboflavin is the best supported ingredient signal for this outcome.

Dose matchedDoseFit 90

Scores reward products dosed inside or above the studied range, not just the right ingredient. Examples: In range: Riboflavin 400 mg vs 400-400 mg.

Processed

6.3k

Available

6.3k

Ingredients

Brands

465

Coverage

100%

Relevant ingredients

Which ingredient types matter for migraine severityOpen to see which ingredient types matter for migraine severity

7.6k products across 6 ingredient types — open to filter the ranking.

Use types to filter ranked products

Minerals & Trace Elements

3.2k products

Inorganic nutrients from calcium to zinc. The chemical form drives absorption – chelates and citrates usually beat cheap oxides.

Typical: , , , ...

Vitamins

2.3k products

Essential micronutrients the body can't make in sufficient amounts. Fat-soluble ones (A, D, E, K) store up; water-soluble ones need regular topping-up.

Typical: , ,

Antioxidants & Bioactive Compounds

819 products

Molecules that neutralize free radicals and tune cell signaling. Helpful in balance; mega-doses can blunt the body's own adaptive defenses.

Typical: , ,

Hormones & Hormone-like Compounds

620 products

Compounds that signal like the body's own hormones — melatonin, DHEA, pregnenolone. Powerful at tiny doses and easy to overdo; timing matters more than potency.

Typical:

Botanicals/Herbal Extracts

410 products

Concentrated plant and herbal extracts standardized to actives. Potency depends on the extract ratio and marker content, not raw weight.

Typical:

Amino Acids & Derivatives

186 products

The building blocks of protein, taken singly for targeted effects – leucine for muscle, theanine for calm. Free-form versions absorb fast on an empty stomach.

Typical:

Top decision cards

Best products for migraine severity

Ranking by · Composite outcome score

Best overall — the composite outcome score.

Top pick · DoseRank

Why this ranks #1 for migraine severity

Nutricost, Vitamin B2, 400 mg, 120 Capsules

Nutricost$0.11 / serving4.8 · 1,486Available now

Also helps with

Riboflavin status

Why this ranks here

Evidence fitRiboflavin is the strongest evidence signal for this outcome.
Dose fitRiboflavin at 400 mg lands inside the studied 400-400 mg window.
Price / serving$0.11 per serving — mid price tier for this outcome.
AvailabilityIn stock across major retailers; 99% availability confidence.
TrustSolid trust signals from buyer ratings, with room to grow.

The numbers

400 mgIn rangeinside the studied 400-400 mg window

Compare top 3 Product data Open at retailer

The rest of the ranking · DoseRank

Top 10 ranked products

Best Naturals, Vitamin B-2 (Riboflavin), 400 mg, 120 Vegetarian Capsules

Best NaturalsClinical89Dose fit90Popularity80$0.11/ serving

NOW Foods, Magnesium Citrate Pure Powder, 8 oz (227 g)

NOW FoodsClinical87Dose fit73Popularity91$0.15/ serving

Forest Leaf, Riboflavin Vitamin B2, 400 mg, 90 Vegetable Capsules

Forest LeafClinical89Dose fit90Popularity68$0.18/ serving

NOW Foods, Magnesium Citrate, 200 mg, 250 Tablets

NOW FoodsClinical86Dose fit67Popularity98$0.19/ serving

Natural Factors, Magnesium Citrate, 360 Capsules (150 mg per Capsule)

Natural FactorsClinical87Dose fit73Popularity89$0.22/ serving

Nature's Way, Riboflavin Vitamin B2, 400 mg, 30 Tablets

Nature's WayClinical89Dose fit90Popularity91$0.43/ serving

Solgar, Magnesium Citrate, 120 Tablets (200 mg per Tablet)

SolgarClinical86Dose fit67Popularity98$0.21/ serving

Micro Ingredients, Magnesium Glycinate, 240 Capsules (166 mg per Capsule)

Micro IngredientsClinical88Dose fit78Popularity91$0.34/ serving

Micro Ingredients, Pure Magnesium Glycinate, 240 Capsules

Micro IngredientsClinical87Dose fit67Popularity91$0.22/ serving