Is a higher dose always better?

No. Dose-fit rewards landing inside the range studied for the outcome — over-dosing (common with melatonin) or under-dosing both lower the score. The goal is the effective dose, not the biggest number.

What does the Value score mean?

The Value score compares a product's price per serving with clinically relevant products ranked for the same outcome. A score of 50 is the typical price; above 50 means better value than typical, while below 50 means the product costs more than typical. It is a 0–100 value signal, not a percentile.

Why is the cheapest product not #1?

Cost is only one input. The cheapest pick here is a citrate form with weaker absorption and a stock-risk flag, so it leads on Value-for-cost but trails on the composite that also weighs evidence, dose fit and availability.

Are these affiliate links?

Retailer links may be affiliate links and DoseRank may earn a commission. Rankings and placement are determined by the scoring model only — never by payment from a brand.

Is this medical advice?

No. DoseRank summarizes evidence to help you choose; it is not a substitute for a clinician, especially if you are pregnant, breastfeeding, on medication, or managing a health condition.

Reduce IBD activity

What this outcome means

Inflammatory bowel disease activity reflects how active conditions like Crohn's or colitis are, measured through symptoms and gut inflammation. On DoseRank it maps to a defined health outcome built from human studies on clinical activity indices, fecal calprotectin, and endoscopic inflammation scores – data sourced from open sources and specialized resources. DoseRank is not medical advice.

Who it's for

Flare-prone gutPeople with IBD whose symptoms swing between calm and flare.

Seeking remissionPatients working to settle gut inflammation and hold it steady.

Marker monitoredThose tracking calprotectin or scope results to gauge disease activity.

Stack buildersAlready taking supplements such as Tributyrin and want the dose right.

Evidence level

60Limited

Evidence score is low, which means that there is not enough data to support the effectiveness of this outcome. However, we will continue to monitor the research and update our recommendations as new information becomes available.

Thin ingredient signal

Tributyrin is the best available ingredient signal for this outcome, but the evidence is still thin.

Dose partly matchedDoseFit 67

Scores reward products dosed inside or above the studied range, not just the right ingredient. Examples: In range: Tributyrin 500 mg vs 500-2000 mg.

Processed

315

Available

315

Ingredients

Brands

101

Coverage

100%

How to read the scores

What every metric means

Each score is 0–100. Higher is better for every metric below.

CompositeThe overall DoseRank score — a weighted blend of clinical strength, evidence, dose fit, trust and value.Higher is better

ClinicalHow strongly the formula's ingredients and doses match what clinical studies used for this outcome.Higher is better

EvidenceHow much published human research backs the formula's key ingredients for this outcome — both how many studies exist and how strong they are.Higher is better

ValueHow the price per serving compares with similar products for this outcome — 50 is the typical price, higher means better value for your money.Higher is better

TrustHow well customers rate this product, with extra weight given to ratings backed by a large number of reviews.Higher is better

PopularityHow strongly this product sells compared with the other ranked products for this outcome.Higher is better

This legend covers the scores on this page — for data sources, scoring weights, and limits, read the full methodology →

Not sure which is right for you?

Answer a few questions about your goals, habits, stack, and budget. Then, DoseRank will find the products that best match your needs based on your answers. It's free and only takes 60 seconds! No account is required.

Take 60-sec quiz

Get a personal report

A saved, shareable breakdown: your matched products, dose math, interaction flags to discuss with a clinician, and a price-tracked stack you can revisit.

Questions

Frequently asked

Each product gets a composite score blending clinical strength, evidence, dose fit, trust and value. The #1 on the DoseRank tab has the highest composite; the other tabs re-rank the same products by Value, Trust, or Popularity. Placement is never paid.

Reduce IBD activity

What this outcome means

Who it's for

Flare-prone gutPeople with IBD whose symptoms swing between calm and flare.

Seeking remissionPatients working to settle gut inflammation and hold it steady.

Marker monitoredThose tracking calprotectin or scope results to gauge disease activity.

Stack buildersAlready taking supplements such as Tributyrin and want the dose right.

Evidence level

60Limited

Thin ingredient signal

Tributyrin is the best available ingredient signal for this outcome, but the evidence is still thin.

Dose partly matchedDoseFit 67

Scores reward products dosed inside or above the studied range, not just the right ingredient. Examples: In range: Tributyrin 500 mg vs 500-2000 mg.

Processed

315

Available

315

Ingredients

Brands

101

Coverage

100%

Relevant ingredients

Which ingredient types matter for inflammatory bowel disease activityOpen to see which ingredient types matter for inflammatory bowel disease activity

15 products across 1 ingredient types — open to filter the ranking.

Use types to filter ranked products

Fatty Acids & Lipids

15 products

Dietary fats including omega-3s and structural lipids. Look at the active EPA/DHA amounts and freshness, since oils oxidize and turn rancid.

Typical:

Top decision cards

Best products for inflammatory bowel disease activity

Ranking by · Composite outcome score

Best overall — the composite outcome score.

Top pick · DoseRank

Why this ranks #1 for inflammatory bowel disease activity

Deva, Vegan Tributyrin, 500 mg , 90 Vegan Caps

Deva$0.22 / serving4.7 · 949Available now

Also helps with

Gut barrier function

Intestinal permeability

Why this ranks here

Evidence fitEvidence is still thin for Tributyrin.
Dose fitTributyrin at 500 mg lands inside the studied 500-2000 mg window.
Price / serving$0.22 per serving — low price tier for this outcome.
AvailabilityIn stock across major retailers; 99% availability confidence.
TrustSolid trust signals from buyer ratings, with room to grow.

The numbers

500 mgIn rangeinside the studied 500-2000 mg window

Compare top 3 Product data Open at retailer

The rest of the ranking · DoseRank

Top 10 ranked products

MaryRuth's, Complete Gut Health, 60 Capsules

MaryRuth'sClinical35Dose fit67Popularity50$1.35/ serving

Irwin Naturals, Sleep Fit + PM Fat Burner, 60 Liquid Softgels

Irwin NaturalsClinical35Dose fit67Popularity30$1.12/ serving

Swanson Vitamins, Boswellia, 400 mg, 100 Capsules

Swanson VitaminsClinical19Dose fit42Popularity50$0.22/ serving

Doctor's Best, Postbiotic Butyrate, High Absorption , 30 Liquid-Filled Veggie Capsules (300 mg per Capsule)

Doctor's BestClinical8Dose fit9Popularity89$0.69/ serving

Beekeeper's Naturals, Propolis Complete Gut Health, 60 Vegetable Capsules

Beekeeper's NaturalsClinical8Dose fit9Popularity50$1.42/ serving

Ritual, Synbiotic+®, Mint, 30 Vegan Capsules

RitualClinical8Dose fit9Popularity80$1.80/ serving

Dr. Emil Nutrition, Total Gut Complex, 60 Capsules

Dr. Emil NutritionClinical8Dose fit9Popularity30$1.47/ serving

Swanson Vitamins, Boswellia Serrata, 120 Capsules

Swanson VitaminsClinical4Dose fit6Popularity76$0.17/ serving

Terry Naturally, BosMed 500, Advanced Boswellia, 500 mg, 120 Softgels

Terry NaturallyClinical4Dose fit6Popularity50$0.56/ serving