DOSERANKEVIDENCE-BASED SUPPLEMENTS
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DOSERANKEVIDENCE-BASED SUPPLEMENTS
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  2. ·Outcomes
  3. ·Inflammation
  4. ·Swelling or inflammation

Reduce swelling and inflammation

View top productsTake the 60-sec quizGet the reportSee methodology

What this outcome means

Swelling or inflammation is the puffiness, warmth, redness, or tenderness that shows up when tissue is irritated or healing. On DoseRank it maps to a defined health outcome built from human studies on visible swelling, joint or tissue tenderness, and inflammatory markers – data sourced from open sources and specialized resources. DoseRank is not medical advice.

Who it's for

Achy jointsStiff, puffy knees or knuckles that flare after activity.
Post-exercise swellingTissue that stays sore and inflamed long after a hard workout.
Lingering puffinessPersistent swelling in tissue that is slow to settle down.
Stack buildersAlready taking supplements such as Bromelain and want the dose right.

Evidence level

78Moderate-strong

Bromelain – has moderate public evidence for this outcome. This usually means there are smaller or mechanistic studies, but not randomized human trials. A DoseFit Score of 79 means this product's ingredient forms and doses are close to what was used in the studies behind this ranking - DoseRank weights each product ingredient.

Best available ingredients

Bromelain is the best supported ingredient signal for this outcome.

Dose matchedDoseFit 79

Scores reward products dosed inside or above the studied range, not just the right ingredient. Examples: In range: Bromelain 625 mg vs 200-1000 mg.

ProcessedProcessedEvery product DoseRank ingested and scored for this outcome, before any availability or relevance filtering.
687
AvailableAvailableOf the products processed, how many are currently in stock and purchasable from a tracked retailer.
687
IngredientsIngredientsNumber of relevant ingredients for this outcome. Each is judged on its own evidence and dose fit score.
3
BrandsBrandsNumber of unique brands represented across the ranked products for this outcome.
131
CoverageCoverageHigher is betterShare of the relevant, in-stock market DoseRank has structured data for. Higher coverage means fewer blind spots in the ranking.
100%

How to read the scores

What every metric means

Each score is 0–100. Higher is better for every metric below.
CompositeThe overall DoseRank score — a weighted blend of clinical strength, evidence, dose fit, trust and value.Higher is better
ClinicalHow strongly the formula's ingredients and doses match what clinical studies used for this outcome.Higher is better
EvidenceHow much published human research backs the formula's key ingredients for this outcome — both how many studies exist and how strong they are.Higher is better
ValueHow the price per serving compares with similar products for this outcome — 50 is the typical price, higher means better value for your money.Higher is better
TrustHow well customers rate this product, with extra weight given to ratings backed by a large number of reviews.Higher is better
PopularityHow strongly this product sells compared with the other ranked products for this outcome.Higher is better

This legend covers the scores on this page — for data sources, scoring weights, and limits, read the full methodology →

Not sure which is right for you?

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Get a personal report

A saved, shareable breakdown: your matched products, dose math, interaction flags to discuss with a clinician, and a price-tracked stack you can revisit.

Questions

Frequently asked

Each product gets a composite score blending clinical strength, evidence, dose fit, trust and value. The #1 on the DoseRank tab has the highest composite; the other tabs re-rank the same products by Value, Trust, or Popularity. Placement is never paid.

No. Dose-fit rewards landing inside the range studied for the outcome — over-dosing (common with melatonin) or under-dosing both lower the score. The goal is the effective dose, not the biggest number.

The Value score compares a product's price per serving with clinically relevant products ranked for the same outcome. A score of 50 is the typical price; above 50 means better value than typical, while below 50 means the product costs more than typical. It is a 0–100 value signal, not a percentile.

Cost is only one input. The cheapest pick here is a citrate form with weaker absorption and a stock-risk flag, so it leads on Value-for-cost but trails on the composite that also weighs evidence, dose fit and availability.

Retailer links may be affiliate links and DoseRank may earn a commission. Rankings and placement are determined by the scoring model only — never by payment from a brand.

No. DoseRank summarizes evidence to help you choose; it is not a substitute for a clinician, especially if you are pregnant, breastfeeding, on medication, or managing a health condition.

DoseRank is not medical advice. Scores summarize publicly available product and study data to help you compare options; they are not a diagnosis or a treatment recommendation. If you are pregnant, breastfeeding, taking medication, or managing a health condition, consult a qualified clinician before starting any supplement. Retailer links may be affiliate links and DoseRank may earn a commission — rankings and placement are determined by the scoring model only, never by payment from a brand. Statements about supplements have not been evaluated by the FDA. Products are not intended to diagnose, treat, cure, or prevent any disease.

Relevant ingredients

Which ingredient types matter for swelling or inflammationOpen to see which ingredient types matter for swelling or inflammation

574 products across 1 ingredient types — open to filter the ranking.
Use types to filter ranked products

Enzymes

574 products

Proteins that speed specific reactions, from digesting food to thinning fibrin. Taken with meals for digestion or away from food for systemic effects.

Typical: ,

Top decision cards

Best products for swelling or inflammation

Ranking by · Composite outcome score

Best overall — the composite outcome score.

Top pick · DoseRank

Why this ranks #1 for swelling or inflammation

#1

California Gold Nutrition, Bromelain, 625 mg, 30 Veggie Capsules

California Gold Nutrition$0.19 / serving4.7 · 6,345Available now
Also helps withSinus symptomsWound healing

Why this ranks here

  • Evidence fitBromelain has moderate human evidence for this outcome.
  • Dose fitBromelain at 625 mg lands inside the studied 200-1000 mg window.
  • Price / serving$0.19 per serving — mid price tier for this outcome.
  • AvailabilityIn stock across major retailers; 99% availability confidence.
  • TrustStrong trust signals — consistently high marks from verified buyer ratings.

The numbers

84
88
79
66

625 mgIn rangeinside the studied 200-1000 mg window
Compare top 3Product dataOpen at retailer

The rest of the ranking · DoseRank

Top 10 ranked products
#ProductPrice
2

Source Naturals, Bromelain 600 GDU/g, 120 Tablets

Source Naturals
Clinical87Dose fit75Popularity80$0.09/ serving
3

NOW Foods, Bromelain, 500 mg (2,400 GDU/g), 120 Veg Capsules

NOW Foods
Clinical87Dose fit75Popularity91$0.20/ serving
4

Nutricost, Bromelain, Unflavored , 4 oz (113 g)

Nutricost
Clinical89Dose fit90Popularity68$0.16/ serving
5

NOW Foods, Bromelain, 500 mg, 60 Veg Capsules

NOW Foods
Clinical87Dose fit75Popularity84$0.23/ serving
6

Doctor's Best, High Potency Bromelain, 500 mg, 90 Veggie Caps

Doctor's Best
Clinical87Dose fit75Popularity91$0.28/ serving
7

Life Extension, Bromelain, Specially-Coated , 60 Enteric Coated Vegetarian Tablets

Life Extension
Clinical87Dose fit75Popularity91$0.24/ serving
8

Vitamatic, Bromelain, 500 mg , 180 Vegetarian Capsules

Vitamatic
Clinical87Dose fit75Popularity76$0.12/ serving
9

Nutricost, Bromelain, 500 mg, 120 Capsules

Nutricost
Clinical87Dose fit75Popularity68$0.13/ serving
10

Natural Factors, Bromelain, 500 mg, 180 Capsules

Natural Factors
Clinical87Dose fit75Popularity50$0.13/ serving

Keep exploring

Related outcomes

C-reactive proteinAcute-phase inflammatory marker.Inflammation biomarkersLaboratory measures of systemic or local inflammation.
Last updated Aug 20, 2026

DoseRank is not medical advice. Scores summarize publicly available product and study data to help you compare options; they are not a diagnosis or a treatment recommendation. If you are pregnant, breastfeeding, taking medication, or managing a health condition, consult a qualified clinician before starting any supplement. Retailer links may be affiliate links and DoseRank may earn a commission — rankings and placement are determined by the scoring model only, never by payment from a brand. Statements about supplements have not been evaluated by the FDA. Products are not intended to diagnose, treat, cure, or prevent any disease.

Comparison preview

Compare the top 3, side by side

Sign-in to see all metrics

The top three for the current view — free to read, no account. Saving, exporting, alerts and the full filter set unlock once you sign in or build a personal report.

Metric
#1California Gold Nutrition, Bromelain, 625 mg, 30 Veggie CapsulesCalifornia Gold Nutrition · $0.19/serving
#2Source Naturals, Bromelain 600 GDU/g, 120 TabletsSource Naturals · $0.09/serving
#3NOW Foods, Bromelain, 500 mg (2,400 GDU/g), 120 Veg CapsulesNOW Foods · $0.20/serving
Composite848483
Clinical888787
Dose fit797575
Value668065
Popularity918091
Key dosages & price · raw values
625 mgHighest500 mg500 mg
Rating
Number of ratings
Price
Price per serving
Serving size
Trust

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Unlocks with accountFull list of ingredients and dosagesFull list of metricsPrice-drop alertsRanking-changes alertsPersistent stack