How does DoseRank decide what ranks #1?

Each product gets a composite score blending clinical strength, evidence, dose fit, trust and value. The #1 on the DoseRank tab has the highest composite; the other tabs re-rank the same products by Value, Trust, or Popularity. Placement is never paid.

Is a higher dose always better?

No. Dose-fit rewards landing inside the range studied for the outcome — over-dosing (common with melatonin) or under-dosing both lower the score. The goal is the effective dose, not the biggest number.

What does the Value score mean?

The Value score compares a product's price per serving with clinically relevant products ranked for the same outcome. A score of 50 is the typical price; above 50 means better value than typical, while below 50 means the product costs more than typical. It is a 0–100 value signal, not a percentile.

Why is the cheapest product not #1?

Cost is only one input. The cheapest pick here is a citrate form with weaker absorption and a stock-risk flag, so it leads on Value-for-cost but trails on the composite that also weighs evidence, dose fit and availability.

Are these affiliate links?

Retailer links may be affiliate links and DoseRank may earn a commission. Rankings and placement are determined by the scoring model only — never by payment from a brand.

Is this medical advice?

No. DoseRank summarizes evidence to help you choose; it is not a substitute for a clinician, especially if you are pregnant, breastfeeding, on medication, or managing a health condition.

DOSERANKEVIDENCE-BASED SUPPLEMENTS

Lower AST

DOSERANKEVIDENCE-BASED SUPPLEMENTS

Best Supplements for Aspartate aminotransferase (AST) | DOSERANK

Top decision cards

Best products for aspartate aminotransferase (ast)

Ranking by · Composite outcome score

Best overall — the composite outcome score.

Top pick · DoseRank

Why this ranks #1 for aspartate aminotransferase (ast)

NOW Foods, Milk Thistle Extract, 300 mg, 200 Veg Capsules

NOW Foods$0.12 / serving4.8 · 64,614Available now

Also helps with

Alanine aminotransferase (ALT)

Liver function

Antioxidant capacity

Why this ranks here

Evidence fitSilymarin is the strongest evidence signal for this outcome.
Dose fitSilymarin at 240 mg lands inside the studied 140-700 mg window.
Price / serving$0.12 per serving — mid price tier for this outcome.
AvailabilityIn stock across major retailers; 99% availability confidence.
TrustStrong trust signals — consistently high marks from verified buyer ratings.

The numbers

240 mgIn rangeinside the studied 140-700 mg window

50 mg

100 mg

Compare top 3 Product data Open at retailer

The rest of the ranking · DoseRank

Top 10 ranked products

NOW Foods, Milk Thistle Extract, 750 mg, 90 Veg Capsules

NOW FoodsClinical88Dose fit86Popularity98$0.26/ serving

NOW Foods, Milk Thistle Extract, 50 Veg Capsules

NOW FoodsClinical87Dose fit71Popularity91$0.19/ serving

NOW Foods, Milk Thistle Extract with Turmeric, 120 Veg Capsules

NOW FoodsClinical87Dose fit71Popularity89$0.21/ serving

California Gold Nutrition, Milk Thistle Plus with Turmeric Extract and Artichoke Extract, 120 Veggie Capsules

California Gold NutritionClinical86Dose fit67Popularity91$0.12/ serving

Solgar, Milk Thistle, 250 Vegetable Capsules (450 mg per Capsule)

SolgarClinical87Dose fit76Popularity50$0.14/ serving

NOW Foods, Liver Refresh™, 180 Veg Capsules

NOW FoodsClinical87Dose fit71Popularity91$0.47/ serving

Solgar, Milk Thistle, 100 Vegetable Capsules (450 mg per Capsule)

SolgarClinical87Dose fit76Popularity50$0.17/ serving

California Gold Nutrition, Advanced Liver Support with Milk Thistle Extract, L-Glutathione, Alpha Lipoic Acid, and Grape Seed Extract, 90 Veggie Capsules

California Gold NutritionClinical87Dose fit71Popularity96$0.44/ serving

Nature's Way, Thisilyn®, Milk Thistle Extract, 100 Vegan Capsules (175 mg per Capsule)

Nature's WayClinical86Dose fit67Popularity80$0.27/ serving

Top decision cards

Best products for aspartate aminotransferase (ast)

Ranking by · Composite outcome score

Best overall — the composite outcome score.

Top pick · DoseRank

Why this ranks #1 for aspartate aminotransferase (ast)

NOW Foods, Milk Thistle Extract, 300 mg, 200 Veg Capsules

NOW Foods$0.12 / serving4.8 · 64,614Available now

Also helps with

Alanine aminotransferase (ALT)

Liver function

Antioxidant capacity

Why this ranks here

Evidence fitSilymarin is the strongest evidence signal for this outcome.
Dose fitSilymarin at 240 mg lands inside the studied 140-700 mg window.
Price / serving$0.12 per serving — mid price tier for this outcome.
AvailabilityIn stock across major retailers; 99% availability confidence.
TrustStrong trust signals — consistently high marks from verified buyer ratings.

The numbers

240 mgIn rangeinside the studied 140-700 mg window

50 mg

100 mg

Compare top 3 Product data Open at retailer

The rest of the ranking · DoseRank

Top 10 ranked products

NOW Foods, Milk Thistle Extract, 750 mg, 90 Veg Capsules

NOW FoodsClinical88Dose fit86Popularity98$0.26/ serving

NOW Foods, Milk Thistle Extract, 50 Veg Capsules

NOW FoodsClinical87Dose fit71Popularity91$0.19/ serving

NOW Foods, Milk Thistle Extract with Turmeric, 120 Veg Capsules

NOW FoodsClinical87Dose fit71Popularity89$0.21/ serving

California Gold Nutrition, Milk Thistle Plus with Turmeric Extract and Artichoke Extract, 120 Veggie Capsules

California Gold NutritionClinical86Dose fit67Popularity91$0.12/ serving

Solgar, Milk Thistle, 250 Vegetable Capsules (450 mg per Capsule)

SolgarClinical87Dose fit76Popularity50$0.14/ serving

NOW Foods, Liver Refresh™, 180 Veg Capsules

NOW FoodsClinical87Dose fit71Popularity91$0.47/ serving

Solgar, Milk Thistle, 100 Vegetable Capsules (450 mg per Capsule)

SolgarClinical87Dose fit76Popularity50$0.17/ serving

California Gold Nutrition, Advanced Liver Support with Milk Thistle Extract, L-Glutathione, Alpha Lipoic Acid, and Grape Seed Extract, 90 Veggie Capsules

California Gold NutritionClinical87Dose fit71Popularity96$0.44/ serving

Nature's Way, Thisilyn®, Milk Thistle Extract, 100 Vegan Capsules (175 mg per Capsule)

Nature's WayClinical86Dose fit67Popularity80$0.27/ serving

Lower AST

Lower AST

Which ingredient types matter for aspartate aminotransferase (ast)Open to see which ingredient types matter for aspartate aminotransferase (ast)

Botanicals/Herbal Extracts

Best products for aspartate aminotransferase (ast)

NOW Foods, Milk Thistle Extract, 300 mg, 200 Veg Capsules

NOW Foods, Milk Thistle Extract, 750 mg, 90 Veg Capsules

NOW Foods, Milk Thistle Extract, 50 Veg Capsules

NOW Foods, Milk Thistle Extract with Turmeric, 120 Veg Capsules

California Gold Nutrition, Milk Thistle Plus with Turmeric Extract and Artichoke Extract, 120 Veggie Capsules

Solgar, Milk Thistle, 250 Vegetable Capsules (450 mg per Capsule)

NOW Foods, Liver Refresh™, 180 Veg Capsules

Solgar, Milk Thistle, 100 Vegetable Capsules (450 mg per Capsule)

California Gold Nutrition, Advanced Liver Support with Milk Thistle Extract, L-Glutathione, Alpha Lipoic Acid, and Grape Seed Extract, 90 Veggie Capsules

Nature's Way, Thisilyn®, Milk Thistle Extract, 100 Vegan Capsules (175 mg per Capsule)

What every metric means

Compare the top 3, side by side

Not sure which is right for you?

Get a personal report

Frequently asked

Which ingredient types matter for aspartate aminotransferase (ast)Open to see which ingredient types matter for aspartate aminotransferase (ast)

Botanicals/Herbal Extracts

Compare the top 3, side by side

Best products for aspartate aminotransferase (ast)

NOW Foods, Milk Thistle Extract, 300 mg, 200 Veg Capsules

NOW Foods, Milk Thistle Extract, 750 mg, 90 Veg Capsules

NOW Foods, Milk Thistle Extract, 50 Veg Capsules

NOW Foods, Milk Thistle Extract with Turmeric, 120 Veg Capsules

California Gold Nutrition, Milk Thistle Plus with Turmeric Extract and Artichoke Extract, 120 Veggie Capsules

Solgar, Milk Thistle, 250 Vegetable Capsules (450 mg per Capsule)

NOW Foods, Liver Refresh™, 180 Veg Capsules

Solgar, Milk Thistle, 100 Vegetable Capsules (450 mg per Capsule)

California Gold Nutrition, Advanced Liver Support with Milk Thistle Extract, L-Glutathione, Alpha Lipoic Acid, and Grape Seed Extract, 90 Veggie Capsules

Nature's Way, Thisilyn®, Milk Thistle Extract, 100 Vegan Capsules (175 mg per Capsule)

Lower AST

Lower AST

Which ingredient types matter for aspartate aminotransferase (ast)Open to see which ingredient types matter for aspartate aminotransferase (ast)

Botanicals/Herbal Extracts

Best products for aspartate aminotransferase (ast)

NOW Foods, Milk Thistle Extract, 300 mg, 200 Veg Capsules

NOW Foods, Milk Thistle Extract, 750 mg, 90 Veg Capsules

NOW Foods, Milk Thistle Extract, 50 Veg Capsules

NOW Foods, Milk Thistle Extract with Turmeric, 120 Veg Capsules

California Gold Nutrition, Milk Thistle Plus with Turmeric Extract and Artichoke Extract, 120 Veggie Capsules

Solgar, Milk Thistle, 250 Vegetable Capsules (450 mg per Capsule)

NOW Foods, Liver Refresh™, 180 Veg Capsules

Solgar, Milk Thistle, 100 Vegetable Capsules (450 mg per Capsule)

California Gold Nutrition, Advanced Liver Support with Milk Thistle Extract, L-Glutathione, Alpha Lipoic Acid, and Grape Seed Extract, 90 Veggie Capsules

Nature's Way, Thisilyn®, Milk Thistle Extract, 100 Vegan Capsules (175 mg per Capsule)

What every metric means

Compare the top 3, side by side

Not sure which is right for you?

Get a personal report

Frequently asked

Related outcomes

Related outcomes

Which ingredient types matter for aspartate aminotransferase (ast)Open to see which ingredient types matter for aspartate aminotransferase (ast)

Botanicals/Herbal Extracts

Compare the top 3, side by side

Best products for aspartate aminotransferase (ast)

NOW Foods, Milk Thistle Extract, 300 mg, 200 Veg Capsules

NOW Foods, Milk Thistle Extract, 750 mg, 90 Veg Capsules

NOW Foods, Milk Thistle Extract, 50 Veg Capsules

NOW Foods, Milk Thistle Extract with Turmeric, 120 Veg Capsules

California Gold Nutrition, Milk Thistle Plus with Turmeric Extract and Artichoke Extract, 120 Veggie Capsules

Solgar, Milk Thistle, 250 Vegetable Capsules (450 mg per Capsule)

NOW Foods, Liver Refresh™, 180 Veg Capsules

Solgar, Milk Thistle, 100 Vegetable Capsules (450 mg per Capsule)

California Gold Nutrition, Advanced Liver Support with Milk Thistle Extract, L-Glutathione, Alpha Lipoic Acid, and Grape Seed Extract, 90 Veggie Capsules

Nature's Way, Thisilyn®, Milk Thistle Extract, 100 Vegan Capsules (175 mg per Capsule)