DOSERANKEVIDENCE-BASED SUPPLEMENTS
DOSERANKEVIDENCE-BASED SUPPLEMENTS© 2026 DoseRank · Evidence-based supplements
Methodology·Outcomes·Categories
DOSERANKEVIDENCE-BASED SUPPLEMENTS
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  2. ·Outcomes
  3. ·Infection prevention
  4. ·Gastrointestinal infection incidence

Reduce gastrointestinal infections

View top productsTake the 60-sec quizGet the reportSee methodology

What this outcome means

Gastrointestinal infection incidence is how often you come down with gut infections — the diarrhea, cramping, and upset that follow a bug. On DoseRank it maps to a defined health outcome built from human studies on infection episode counts, illness duration, and confirmed pathogen rates – data sourced from open sources and specialized resources. DoseRank is not medical advice.

Who it's for

Frequent travelersPeople exposed to new food and water that upset the gut.
Recurrent bugsThose who catch stomach infections more often than most.
Shared-space exposureParents and caregivers around children who pass infections around.
Stack buildersAlready taking supplements such as Saccharomyces boulardii and want the dose right.

Evidence level

92Strong

Saccharomyces boulardii – has strong public evidence. DoseRank looks at both evidence quality and formula fit. A DoseFit Score of 67 means this product's ingredient forms and doses are close to what was used in the studies behind this ranking - DoseRank weights each product ingredient.

Best ingredients

Saccharomyces boulardii is the best supported ingredient signal for this outcome.

Dose partly matchedDoseFit 67

Scores reward products dosed inside or above the studied range, not just the right ingredient. Examples: In range: Saccharomyces boulardii 500 mg vs 500-1000 mg.

ProcessedProcessedEvery product DoseRank ingested and scored for this outcome, before any availability or relevance filtering.
926
AvailableAvailableOf the products processed, how many are currently in stock and purchasable from a tracked retailer.
926
IngredientsIngredientsNumber of relevant ingredients for this outcome. Each is judged on its own evidence and dose fit score.
6
BrandsBrandsNumber of unique brands represented across the ranked products for this outcome.
188
CoverageCoverageHigher is betterShare of the relevant, in-stock market DoseRank has structured data for. Higher coverage means fewer blind spots in the ranking.
100%

How to read the scores

What every metric means

Each score is 0–100. Higher is better for every metric below.
CompositeThe overall DoseRank score — a weighted blend of clinical strength, evidence, dose fit, trust and value.Higher is better
ClinicalHow strongly the formula's ingredients and doses match what clinical studies used for this outcome.Higher is better
EvidenceHow much published human research backs the formula's key ingredients for this outcome — both how many studies exist and how strong they are.Higher is better
ValueHow the price per serving compares with similar products for this outcome — 50 is the typical price, higher means better value for your money.Higher is better
TrustHow well customers rate this product, with extra weight given to ratings backed by a large number of reviews.Higher is better
PopularityHow strongly this product sells compared with the other ranked products for this outcome.Higher is better

This legend covers the scores on this page — for data sources, scoring weights, and limits, read the full methodology →

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A saved, shareable breakdown: your matched products, dose math, interaction flags to discuss with a clinician, and a price-tracked stack you can revisit.

Questions

Frequently asked

Each product gets a composite score blending clinical strength, evidence, dose fit, trust and value. The #1 on the DoseRank tab has the highest composite; the other tabs re-rank the same products by Value, Trust, or Popularity. Placement is never paid.

DoseRank is not medical advice. Scores summarize publicly available product and study data to help you compare options; they are not a diagnosis or a treatment recommendation. If you are pregnant, breastfeeding, taking medication, or managing a health condition, consult a qualified clinician before starting any supplement. Retailer links may be affiliate links and DoseRank may earn a commission — rankings and placement are determined by the scoring model only, never by payment from a brand. Statements about supplements have not been evaluated by the FDA. Products are not intended to diagnose, treat, cure, or prevent any disease.

Relevant ingredients

Which ingredient types matter for gastrointestinal infection incidenceOpen to see which ingredient types matter for gastrointestinal infection incidence

603 products across 2 ingredient types — open to filter the ranking.
Use types to filter ranked products

Probiotics & Microorganisms

306 products

Live beneficial bacteria and yeasts measured in CFUs. Strain identity and viability at expiry matter far more than headline colony counts.

Typical: , ,

Fibers & Prebiotics

297 products

Indigestible carbs that feed gut bacteria and add bulk. Start low and ramp slowly – too much too fast means bloating and gas.

Typical:

Top decision cards

Best products for gastrointestinal infection incidence

Ranking by · Composite outcome score

Best overall — the composite outcome score.

Top pick · DoseRank

Why this ranks #1 for gastrointestinal infection incidence

#1

California Gold Nutrition, Epicor®, Dried Yeast Fermentate, 500 mg, 120 Veggie Capsules

California Gold Nutrition$0.21 / serving4.7 · 5,652Available now

Why this ranks here

  • Evidence fitSaccharomyces boulardii is the strongest evidence signal for this outcome.
  • Dose fitSaccharomyces boulardii at 500 mg lands inside the studied 500-1000 mg window.
  • Price / serving$0.21 per serving — mid price tier for this outcome.
  • AvailabilityIn stock across major retailers; 99% availability confidence.
  • TrustStrong trust signals — consistently high marks from verified buyer ratings.

Trade-offs

Dose fit is the weak spot on this listPopularity trails the other picks here

The numbers

85
88
67
71

500 mgIn rangeinside the studied 500-1000 mg window
Compare top 3Product dataOpen at retailer

The rest of the ranking · DoseRank

Top 10 ranked products
#ProductPrice

Keep exploring

Related outcomes

Infection incidenceOverall rate of infectious illness.
Last updated Jun 12, 2026

DoseRank is not medical advice. Scores summarize publicly available product and study data to help you compare options; they are not a diagnosis or a treatment recommendation. If you are pregnant, breastfeeding, taking medication, or managing a health condition, consult a qualified clinician before starting any supplement. Retailer links may be affiliate links and DoseRank may earn a commission — rankings and placement are determined by the scoring model only, never by payment from a brand. Statements about supplements have not been evaluated by the FDA. Products are not intended to diagnose, treat, cure, or prevent any disease.

Comparison preview

Compare the top 3, side by side

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The top three for the current view — free to read, no account. Saving, exporting, alerts and the full filter set unlock once you sign in or build a personal report.

Metric
#1California Gold Nutrition, Epicor®, Dried Yeast Fermentate, 500 mg, 120 Veggie CapsulesCalifornia Gold Nutrition · $0.21/serving
#2Jarrow Formulas, Vegan Saccharomyces Boulardii + MOS, 5 Billion CFU, 90 Veggie CapsulesJarrow Formulas · $0.30/serving
#3NOW Foods, Saccharomyces Boulardii, Probiotic , 5 Billion CFU, 60 Veg CapsulesNOW Foods · $0.43/serving
Composite858484
Clinical888889
Dose fit676790
Value716355
Popularity839899
Key dosages & price · raw values
500 mg500 mg1000 mgHighest
Rating
Number of ratings
Price
Price per serving
Serving size
Trust

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Unlocks with accountFull list of ingredients and dosagesFull list of metricsPrice-drop alertsRanking-changes alertsPersistent stack