DOSERANKEVIDENCE-BASED SUPPLEMENTS
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DOSERANKEVIDENCE-BASED SUPPLEMENTS
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  1. Search
  2. ·Outcomes
  3. ·Fatty liver
  4. ·Hepatic steatosis

Reduce liver fat

View top productsTake the 60-sec quizGet the reportSee methodology

What this outcome means

Hepatic steatosis is the build-up of excess fat inside liver cells, often picked up on a scan or routine blood test before you feel anything. On DoseRank it maps to a defined health outcome built from human studies on liver fat percentage, imaging steatosis grade, and hepatic enzyme levels – data sourced from open sources and specialized resources. DoseRank is not medical advice.

Who it's for

Scan-flagged liverAn ultrasound or scan that noted fatty changes in the liver.
Metabolic profileCarrying extra weight, high blood sugar, or unhealthy lipid numbers.
Borderline enzymesSlightly raised liver enzymes turning up on routine blood work.
Stack buildersAlready taking supplements such as d-Alpha Tocopherol and want the dose right.

Evidence level

92Strong

d-Alpha Tocopherol – has strong public evidence. DoseRank looks at both evidence quality and formula fit. A DoseFit Score of 67 means this product's ingredient forms and doses are close to what was used in the studies behind this ranking - DoseRank weights each product ingredient.

Best ingredients

d-Alpha Tocopherol is the best supported ingredient signal for this outcome.

Dose partly matchedDoseFit 67

Scores reward products dosed inside or above the studied range, not just the right ingredient. Examples: In range: d-Alpha Tocopherol 268 mg vs 268-536 mg.

ProcessedProcessedEvery product DoseRank ingested and scored for this outcome, before any availability or relevance filtering.
3.3k
AvailableAvailableOf the products processed, how many are currently in stock and purchasable from a tracked retailer.
3.3k
IngredientsIngredientsNumber of relevant ingredients for this outcome. Each is judged on its own evidence and dose fit score.
19
BrandsBrandsNumber of unique brands represented across the ranked products for this outcome.
311
CoverageCoverageHigher is betterShare of the relevant, in-stock market DoseRank has structured data for. Higher coverage means fewer blind spots in the ranking.
100%

How to read the scores

What every metric means

Each score is 0–100. Higher is better for every metric below.
CompositeThe overall DoseRank score — a weighted blend of clinical strength, evidence, dose fit, trust and value.Higher is better
ClinicalHow strongly the formula's ingredients and doses match what clinical studies used for this outcome.Higher is better
EvidenceHow much published human research backs the formula's key ingredients for this outcome — both how many studies exist and how strong they are.Higher is better
ValueHow the price per serving compares with similar products for this outcome — 50 is the typical price, higher means better value for your money.Higher is better
TrustHow well customers rate this product, with extra weight given to ratings backed by a large number of reviews.Higher is better
PopularityHow strongly this product sells compared with the other ranked products for this outcome.Higher is better

This legend covers the scores on this page — for data sources, scoring weights, and limits, read the full methodology →

Not sure which is right for you?

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Get a personal report

A saved, shareable breakdown: your matched products, dose math, interaction flags to discuss with a clinician, and a price-tracked stack you can revisit.

Questions

Frequently asked

Each product gets a composite score blending clinical strength, evidence, dose fit, trust and value. The #1 on the DoseRank tab has the highest composite; the other tabs re-rank the same products by Value, Trust, or Popularity. Placement is never paid.

No. Dose-fit rewards landing inside the range studied for the outcome — over-dosing (common with melatonin) or under-dosing both lower the score. The goal is the effective dose, not the biggest number.

The Value score compares a product's price per serving with clinically relevant products ranked for the same outcome. A score of 50 is the typical price; above 50 means better value than typical, while below 50 means the product costs more than typical. It is a 0–100 value signal, not a percentile.

Cost is only one input. The cheapest pick here is a citrate form with weaker absorption and a stock-risk flag, so it leads on Value-for-cost but trails on the composite that also weighs evidence, dose fit and availability.

Retailer links may be affiliate links and DoseRank may earn a commission. Rankings and placement are determined by the scoring model only — never by payment from a brand.

No. DoseRank summarizes evidence to help you choose; it is not a substitute for a clinician, especially if you are pregnant, breastfeeding, on medication, or managing a health condition.

DoseRank is not medical advice. Scores summarize publicly available product and study data to help you compare options; they are not a diagnosis or a treatment recommendation. If you are pregnant, breastfeeding, taking medication, or managing a health condition, consult a qualified clinician before starting any supplement. Retailer links may be affiliate links and DoseRank may earn a commission — rankings and placement are determined by the scoring model only, never by payment from a brand. Statements about supplements have not been evaluated by the FDA. Products are not intended to diagnose, treat, cure, or prevent any disease.

Relevant ingredients

Which ingredient types matter for hepatic steatosisOpen to see which ingredient types matter for hepatic steatosis

2.9k products across 5 ingredient types — open to filter the ranking.
Use types to filter ranked products

Vitamins

2.3k products

Essential micronutrients the body can't make in sufficient amounts. Fat-soluble ones (A, D, E, K) store up; water-soluble ones need regular topping-up.

Typical: , , , ...

Alkaloids & Stimulants

100 products

Plant-derived nitrogen compounds like caffeine that stimulate the nervous system. Effective but dose-sensitive, with real tolerance and dependence risk.

Typical:

Botanicals/Herbal Extracts

216 products

Concentrated plant and herbal extracts standardized to actives. Potency depends on the extract ratio and marker content, not raw weight.

Typical:

Fatty Acids & Lipids

285 products

Dietary fats including omega-3s and structural lipids. Look at the active EPA/DHA amounts and freshness, since oils oxidize and turn rancid.

Typical: , , , ...

Antioxidants & Bioactive Compounds

18 products

Molecules that neutralize free radicals and tune cell signaling. Helpful in balance; mega-doses can blunt the body's own adaptive defenses.

Typical:

Top decision cards

Best products for hepatic steatosis

Ranking by · Composite outcome score

Best overall — the composite outcome score.

Top pick · DoseRank

Why this ranks #1 for hepatic steatosis

#1

NOW Foods, E-400 with Mixed Tocopherols, 268 mg (400 IU), 250 Softgels

NOW Foods$0.11 / serving4.8 · 9,184Available now
Also helps withVitamin E statusAntioxidant capacityAlanine aminotransferase (ALT)

Why this ranks here

  • Evidence fitd-Alpha Tocopherol is the strongest evidence signal for this outcome.
  • Dose fitd-Alpha Tocopherol at 268 mg lands inside the studied 268-536 mg window.
  • Price / serving$0.11 per serving — mid price tier for this outcome.
  • AvailabilityIn stock across major retailers; 99% availability confidence.
  • TrustStrong trust signals — consistently high marks from verified buyer ratings.

The numbers

86
89
67
80

268 mgIn rangeinside the studied 268-536 mg window
Compare top 3Product dataOpen at retailer

The rest of the ranking · DoseRank

Top 10 ranked products
#ProductPrice
2

Solgar, Vitamin E, Naturally Sourced, 100 Softgels

Solgar
Clinical89Dose fit67Popularity91$0.12/ serving
3

Solgar, Vitamin E, 268 mg (400 IU), 100 Softgels

Solgar
Clinical89Dose fit67Popularity89$0.12/ serving
4

Solgar, Vitamin E, Naturally Sourced, 268 mg (400 IU), 250 Softgels

Solgar
Clinical89Dose fit67Popularity84$0.10/ serving
5

NOW Foods, E-400, 268 mg (400 IU), 50 Softgels

NOW Foods
Clinical89Dose fit67Popularity91$0.14/ serving
6

Solaray, Bio E® + Selenium with Lecithin, 120 Softgels

Solaray
Clinical96Dose fit68Popularity30$0.43/ serving
7

California Gold Nutrition, Sunflower Vitamin E with Mixed Tocopherols, 400 IU, 90 Veggie Softgels

California Gold Nutrition
Clinical89Dose fit67Popularity91$0.20/ serving
8

Solgar, Vitamin E, 100 Softgels

Solgar
Clinical89Dose fit91Popularity84$0.23/ serving
9

Life Extension, Super Vitamin E, 268 mg (400 IU), 90 Softgels

Life Extension
Clinical89Dose fit67Popularity84$0.19/ serving
10

Swanson Vitamins, Natural E-400, 268 mg (400 IU), 100 Softgels

Swanson Vitamins
Clinical88Dose fit67Popularity76$0.12/ serving
Last updated Aug 20, 2026

DoseRank is not medical advice. Scores summarize publicly available product and study data to help you compare options; they are not a diagnosis or a treatment recommendation. If you are pregnant, breastfeeding, taking medication, or managing a health condition, consult a qualified clinician before starting any supplement. Retailer links may be affiliate links and DoseRank may earn a commission — rankings and placement are determined by the scoring model only, never by payment from a brand. Statements about supplements have not been evaluated by the FDA. Products are not intended to diagnose, treat, cure, or prevent any disease.

Comparison preview

Compare the top 3, side by side

Sign-in to see all metrics

The top three for the current view — free to read, no account. Saving, exporting, alerts and the full filter set unlock once you sign in or build a personal report.

Metric
#1NOW Foods, E-400 with Mixed Tocopherols, 268 mg (400 IU), 250 SoftgelsNOW Foods · $0.11/serving
#2Solgar, Vitamin E, Naturally Sourced, 100 SoftgelsSolgar · $0.12/serving
#3Solgar, Vitamin E, 268 mg (400 IU), 100 SoftgelsSolgar · $0.12/serving
Composite868686
Clinical898989
Dose fit676767
Value807878
Popularity919189
Key dosages & price · raw values
268 mgHighest268 mgHighest268 mgHighest
Rating
Number of ratings
Price
Price per serving
Serving size
Trust

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