How does DoseRank decide what ranks #1?

Each product gets a composite score blending clinical strength, evidence, dose fit, trust and value. The #1 on the DoseRank tab has the highest composite; the other tabs re-rank the same products by Value, Trust, or Popularity. Placement is never paid.

Is a higher dose always better?

No. Dose-fit rewards landing inside the range studied for the outcome — over-dosing (common with melatonin) or under-dosing both lower the score. The goal is the effective dose, not the biggest number.

What does the Value score mean?

The Value score compares a product's price per serving with clinically relevant products ranked for the same outcome. A score of 50 is the typical price; above 50 means better value than typical, while below 50 means the product costs more than typical. It is a 0–100 value signal, not a percentile.

Why is the cheapest product not #1?

Cost is only one input. The cheapest pick here is a citrate form with weaker absorption and a stock-risk flag, so it leads on Value-for-cost but trails on the composite that also weighs evidence, dose fit and availability.

Are these affiliate links?

Retailer links may be affiliate links and DoseRank may earn a commission. Rankings and placement are determined by the scoring model only — never by payment from a brand.

Is this medical advice?

No. DoseRank summarizes evidence to help you choose; it is not a substitute for a clinician, especially if you are pregnant, breastfeeding, on medication, or managing a health condition.

DOSERANKEVIDENCE-BASED SUPPLEMENTS

Improve vascular function

DOSERANKEVIDENCE-BASED SUPPLEMENTS

Best Supplements for Vascular function — 2609 Ranked | DOSERANK

Top decision cards

Best products for vascular function

Ranking by · Composite outcome score

Best overall — the composite outcome score.

Top pick · DoseRank

Why this ranks #1 for vascular function

Nutricost, Grape Seed Extract, 240 Capsules (400 mg per Capsule)

Nutricost$0.07 / serving4.8 · 1,187Available now

Also helps with

Blood pressure

Antioxidant capacity

Oxidative stress biomarkers

Why this ranks here

Evidence fitGrape Seed Extract has moderate human evidence for this outcome.
Dose fitGrape Seed Extract at 400 mg lands inside the studied 150-400 mg window.
Price / serving$0.07 per serving — low price tier for this outcome.
AvailabilityIn stock across major retailers; 99% availability confidence.
TrustSolid trust signals from buyer ratings, with room to grow.

The numbers

400 mgIn rangeinside the studied 150-400 mg window

Compare top 3 Product data Open at retailer

The rest of the ranking · DoseRank

Top 10 ranked products

Micro Ingredients, Vitamin K2, MK-7, 200 mcg, 300 Softgels

Micro IngredientsClinical86Dose fit76Popularity95$0.07/ serving

Micro Ingredients, Vitamin D3 & K2, 300 Softgels

Micro IngredientsClinical86Dose fit76Popularity97$0.10/ serving

Metabolic Nutrition, Vitamin D3 + K2, 90 Capsules

Metabolic NutritionClinical86Dose fit76Popularity90$0.11/ serving

California Gold Nutrition, Vitamin D3 + K2 as MK-7, 180 Veggie Capsules

California Gold NutritionClinical85Dose fit69Popularity100$0.09/ serving

Nutricost, Vitamin K2 MK-7, 100 mcg, 240 Softgels

NutricostClinical85Dose fit68Popularity98$0.07/ serving

NOW Foods, Grape Seed Extract, 500 mg, 90 Veg Capsules

NOW FoodsClinical88Dose fit91Popularity87$0.26/ serving

NOW Foods, MK-7, Vitamin K-2, 300 mcg, 120 Veg Capsules

NOW FoodsClinical87Dose fit85Popularity90$0.23/ serving

NOW Foods, Mega D3 & MK-7, 120 Capsules

NOW FoodsClinical86Dose fit74Popularity99$0.19/ serving

Codeage, A, D, K Vitamins+, 180 Vegetable Capsules

CodeageClinical88Dose fit94Popularity81$0.22/ serving

Top decision cards

Best products for vascular function

Ranking by · Composite outcome score

Best overall — the composite outcome score.

Top pick · DoseRank

Why this ranks #1 for vascular function

Nutricost, Grape Seed Extract, 240 Capsules (400 mg per Capsule)

Nutricost$0.07 / serving4.8 · 1,187Available now

Also helps with

Blood pressure

Antioxidant capacity

Oxidative stress biomarkers

Why this ranks here

Evidence fitGrape Seed Extract has moderate human evidence for this outcome.
Dose fitGrape Seed Extract at 400 mg lands inside the studied 150-400 mg window.
Price / serving$0.07 per serving — low price tier for this outcome.
AvailabilityIn stock across major retailers; 99% availability confidence.
TrustSolid trust signals from buyer ratings, with room to grow.

The numbers

400 mgIn rangeinside the studied 150-400 mg window

Compare top 3 Product data Open at retailer

The rest of the ranking · DoseRank

Top 10 ranked products

Micro Ingredients, Vitamin K2, MK-7, 200 mcg, 300 Softgels

Micro IngredientsClinical86Dose fit76Popularity95$0.07/ serving

Micro Ingredients, Vitamin D3 & K2, 300 Softgels

Micro IngredientsClinical86Dose fit76Popularity97$0.10/ serving

Metabolic Nutrition, Vitamin D3 + K2, 90 Capsules

Metabolic NutritionClinical86Dose fit76Popularity90$0.11/ serving

California Gold Nutrition, Vitamin D3 + K2 as MK-7, 180 Veggie Capsules

California Gold NutritionClinical85Dose fit69Popularity100$0.09/ serving

Nutricost, Vitamin K2 MK-7, 100 mcg, 240 Softgels

NutricostClinical85Dose fit68Popularity98$0.07/ serving

NOW Foods, Grape Seed Extract, 500 mg, 90 Veg Capsules

NOW FoodsClinical88Dose fit91Popularity87$0.26/ serving

NOW Foods, MK-7, Vitamin K-2, 300 mcg, 120 Veg Capsules

NOW FoodsClinical87Dose fit85Popularity90$0.23/ serving

NOW Foods, Mega D3 & MK-7, 120 Capsules

NOW FoodsClinical86Dose fit74Popularity99$0.19/ serving

Codeage, A, D, K Vitamins+, 180 Vegetable Capsules

CodeageClinical88Dose fit94Popularity81$0.22/ serving

Improve vascular function

Improve vascular function

Which ingredient types matter for vascular functionOpen to see which ingredient types matter for vascular function

Botanicals/Herbal Extracts

Minerals & Trace Elements

Vitamins

Amino Acids & Derivatives

Antioxidants & Bioactive Compounds

Best products for vascular function

Nutricost, Grape Seed Extract, 240 Capsules (400 mg per Capsule)

Micro Ingredients, Vitamin K2, MK-7, 200 mcg, 300 Softgels

Micro Ingredients, Vitamin D3 & K2, 300 Softgels

Metabolic Nutrition, Vitamin D3 + K2, 90 Capsules

California Gold Nutrition, Vitamin D3 + K2 as MK-7, 180 Veggie Capsules

Nutricost, Vitamin K2 MK-7, 100 mcg, 240 Softgels

NOW Foods, Grape Seed Extract, 500 mg, 90 Veg Capsules

NOW Foods, MK-7, Vitamin K-2, 300 mcg, 120 Veg Capsules

NOW Foods, Mega D3 & MK-7, 120 Capsules

Codeage, A, D, K Vitamins+, 180 Vegetable Capsules

What every metric means

Compare the top 3, side by side

Not sure which is right for you?

Get a personal report

Frequently asked

Related outcomes

Related outcomes

Which ingredient types matter for vascular functionOpen to see which ingredient types matter for vascular function

Botanicals/Herbal Extracts

Minerals & Trace Elements

Vitamins

Amino Acids & Derivatives

Antioxidants & Bioactive Compounds

Compare the top 3, side by side

Best products for vascular function

Nutricost, Grape Seed Extract, 240 Capsules (400 mg per Capsule)

Micro Ingredients, Vitamin K2, MK-7, 200 mcg, 300 Softgels

Micro Ingredients, Vitamin D3 & K2, 300 Softgels

Metabolic Nutrition, Vitamin D3 + K2, 90 Capsules

California Gold Nutrition, Vitamin D3 + K2 as MK-7, 180 Veggie Capsules

Nutricost, Vitamin K2 MK-7, 100 mcg, 240 Softgels

NOW Foods, Grape Seed Extract, 500 mg, 90 Veg Capsules

NOW Foods, MK-7, Vitamin K-2, 300 mcg, 120 Veg Capsules

NOW Foods, Mega D3 & MK-7, 120 Capsules

Codeage, A, D, K Vitamins+, 180 Vegetable Capsules