DOSERANKEVIDENCE-BASED SUPPLEMENTS
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DOSERANKEVIDENCE-BASED SUPPLEMENTS
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  3. ·Sleep
  4. ·Night awakenings

Reduce night awakenings

View top productsTake the 60-sec quizGet the reportSee methodology

What this outcome means

Night awakenings are the times you surface from sleep before morning, whether you remember them or simply wake feeling less rested. On DoseRank it maps to a defined health outcome built from human studies on number of nighttime awakenings, wake-after-sleep-onset, and sleep continuity – data sourced from open sources and specialized resources. DoseRank is not medical advice.

Who it's for

Frequent night-wakersPeople who stir several times before the alarm goes off.
Light, easily disturbed sleepThose roused by noise, light, or a restless partner.
Mid-life sleep shiftsPeople finding their nights more broken than they used to be.
Stack buildersAlready taking supplements such as Sustained-Release Melatonin and want the dose right.

Evidence level

92Strong

Sustained-Release Melatonin – has strong public evidence. DoseRank looks at both evidence quality and formula fit. A DoseFit Score of 93 means this product's ingredient forms and doses are close to what was used in the studies behind this ranking - DoseRank weights each product ingredient.

Best ingredients

Sustained-Release Melatonin is the best supported ingredient signal for this outcome.

Dose matchedDoseFit 93

Scores reward products dosed inside or above the studied range, not just the right ingredient. Examples: Above range: Sustained-Release Melatonin 10 mg vs 1-5 mg.

ProcessedProcessedEvery product DoseRank ingested and scored for this outcome, before any availability or relevance filtering.
542
AvailableAvailableOf the products processed, how many are currently in stock and purchasable from a tracked retailer.
542
IngredientsIngredientsNumber of relevant ingredients for this outcome. Each is judged on its own evidence and dose fit score.
2
BrandsBrandsNumber of unique brands represented across the ranked products for this outcome.
100
CoverageCoverageHigher is betterShare of the relevant, in-stock market DoseRank has structured data for. Higher coverage means fewer blind spots in the ranking.
100%

How to read the scores

What every metric means

Each score is 0–100. Higher is better for every metric below.
CompositeThe overall DoseRank score — a weighted blend of clinical strength, evidence, dose fit, trust and value.Higher is better
ClinicalHow strongly the formula's ingredients and doses match what clinical studies used for this outcome.Higher is better
EvidenceHow much published human research backs the formula's key ingredients for this outcome — both how many studies exist and how strong they are.Higher is better
ValueHow the price per serving compares with similar products for this outcome — 50 is the typical price, higher means better value for your money.Higher is better
TrustHow well customers rate this product, with extra weight given to ratings backed by a large number of reviews.Higher is better
PopularityHow strongly this product sells compared with the other ranked products for this outcome.Higher is better

This legend covers the scores on this page — for data sources, scoring weights, and limits, read the full methodology →

Not sure which is right for you?

Answer a few questions about your goals, habits, stack, and budget. Then, DoseRank will find the products that best match your needs based on your answers. It's free and only takes 60 seconds! No account is required.

Take 60-sec quiz

Get a personal report

A saved, shareable breakdown: your matched products, dose math, interaction flags to discuss with a clinician, and a price-tracked stack you can revisit.

Questions

Frequently asked

Each product gets a composite score blending clinical strength, evidence, dose fit, trust and value. The #1 on the DoseRank tab has the highest composite; the other tabs re-rank the same products by Value, Trust, or Popularity. Placement is never paid.

No. Dose-fit rewards landing inside the range studied for the outcome — over-dosing (common with melatonin) or under-dosing both lower the score. The goal is the effective dose, not the biggest number.

The Value score compares a product's price per serving with clinically relevant products ranked for the same outcome. A score of 50 is the typical price; above 50 means better value than typical, while below 50 means the product costs more than typical. It is a 0–100 value signal, not a percentile.

Cost is only one input. The cheapest pick here is a citrate form with weaker absorption and a stock-risk flag, so it leads on Value-for-cost but trails on the composite that also weighs evidence, dose fit and availability.

Retailer links may be affiliate links and DoseRank may earn a commission. Rankings and placement are determined by the scoring model only — never by payment from a brand.

No. DoseRank summarizes evidence to help you choose; it is not a substitute for a clinician, especially if you are pregnant, breastfeeding, on medication, or managing a health condition.

DoseRank is not medical advice. Scores summarize publicly available product and study data to help you compare options; they are not a diagnosis or a treatment recommendation. If you are pregnant, breastfeeding, taking medication, or managing a health condition, consult a qualified clinician before starting any supplement. Retailer links may be affiliate links and DoseRank may earn a commission — rankings and placement are determined by the scoring model only, never by payment from a brand. Statements about supplements have not been evaluated by the FDA. Products are not intended to diagnose, treat, cure, or prevent any disease.

Relevant ingredients

Which ingredient types matter for night awakeningsOpen to see which ingredient types matter for night awakenings

3 products across 1 ingredient types — open to filter the ranking.
Use types to filter ranked products

Hormones & Hormone-like Compounds

3 products

Compounds that signal like the body's own hormones — melatonin, DHEA, pregnenolone. Powerful at tiny doses and easy to overdo; timing matters more than potency.

Typical:

Top decision cards

Best products for night awakenings

Ranking by · Composite outcome score

Best overall — the composite outcome score.

Top pick · DoseRank

Why this ranks #1 for night awakenings

#1

Solaray, Extended Release Melatonin With Glycine, 100 VegCaps

Solaray$0.17 / serving4.7 · 81Available now
Also helps withSleep qualityInsomnia severitySleep duration

Why this ranks here

  • Evidence fitSustained-Release Melatonin is the strongest evidence signal for this outcome.
  • Dose fitSustained-Release Melatonin at 10 mg is higher than the studied 1-5 mg window.
  • Price / serving$0.17 per serving — mid price tier for this outcome.
  • AvailabilityIn stock across major retailers; 99% availability confidence.
  • TrustLimited trust signals so far for this listing.

The numbers

80
89
93
63

10 mgAbove rangehigher than the studied 1-5 mg window

1000 mg
Compare top 3Product dataOpen at retailer

The rest of the ranking · DoseRank

Top 10 ranked products
#ProductPrice
2

Pure Encapsulations, Melatonin-SR, 60 Capsules (3 mg per Capsule)

Pure Encapsulations
Clinical89Dose fit78Popularity30$0.29/ serving
3

Life Extension, Triple Action Blood Pressure, AM/PM, 60 Vegetarian Tablets

Life Extension
Clinical89Dose fit73Popularity30$0.49/ serving
4

MuscleMeds, Carnivor Beef Aminos, 100% Pure Beef Protein, 300 Tablets

MuscleMeds
Clinical3Dose fit91Popularity76$0.22/ serving
5

California Gold Nutrition, MEM Food®, Memory & Cognitive Support with MEM Blend, L-Serine, Organic Lion's Mane and Blueberry Juice Powder, 1.12 lb (510 g)

California Gold Nutrition
Clinical3Dose fit91Popularity84$0.58/ serving
6

California Gold Nutrition, L-Serine Powder, AjiPure Amino Acid, Unflavored Powder, 1 lb (454 g)

California Gold Nutrition
Clinical3Dose fit95Popularity68$0.73/ serving
7

Lake Avenue Nutrition, L-Serine, Unflavored Powder, 1 lb (454 g)

Lake Avenue Nutrition
Clinical3Dose fit95Popularity30$0.95/ serving
8

Designer Wellness, Designer Egg®, Whole Egg Multifunction Protein Powder, Classic Vanilla, 1.55 lb (704 g)

Designer Wellness
Clinical3Dose fit93Popularity30$1.55/ serving
9

Designer Wellness, Designer Egg®, Whole Egg Multifunction Protein Powder, Classic Vanilla, 12.4 oz (352 g)

Designer Wellness
Clinical3Dose fit93Popularity30$2.25/ serving
10

Designer Wellness, Designer Egg®, Whole Egg Multifunction Protein Powder, Dutched Chocolate, 12.4 oz (352 g)

Designer Wellness
Clinical3Dose fit93Popularity30$2.45/ serving

Keep exploring

Related outcomes

Insomnia severityDegree of difficulty initiating or maintaining sleep.Sleep durationTotal amount of sleep obtained.Sleep latencyTime needed to fall asleep.Sleep qualityOverall restfulness and perceived quality of sleep.
Last updated Aug 20, 2026

DoseRank is not medical advice. Scores summarize publicly available product and study data to help you compare options; they are not a diagnosis or a treatment recommendation. If you are pregnant, breastfeeding, taking medication, or managing a health condition, consult a qualified clinician before starting any supplement. Retailer links may be affiliate links and DoseRank may earn a commission — rankings and placement are determined by the scoring model only, never by payment from a brand. Statements about supplements have not been evaluated by the FDA. Products are not intended to diagnose, treat, cure, or prevent any disease.

Comparison preview

Compare the top 3, side by side

Sign-in to see all metrics

The top three for the current view — free to read, no account. Saving, exporting, alerts and the full filter set unlock once you sign in or build a personal report.

Metric
#1Solaray, Extended Release Melatonin With Glycine, 100 VegCapsSolaray · $0.17/serving
#2Pure Encapsulations, Melatonin-SR, 60 Capsules (3 mg per Capsule)Pure Encapsulations · $0.29/serving
#3Life Extension, Triple Action Blood Pressure, AM/PM, 60 Vegetarian TabletsLife Extension · $0.49/serving
Composite807877
Clinical898989
Dose fit937873
Value635037
Popularity303030
Key dosages & price · raw values
10 mgHighest3 mg2 mg
Rating
Number of ratings
Price
Price per serving
Serving size
Trust

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Unlocks with accountFull list of ingredients and dosagesFull list of metricsPrice-drop alertsRanking-changes alertsPersistent stack