DOSERANKEVIDENCE-BASED SUPPLEMENTS
DOSERANKEVIDENCE-BASED SUPPLEMENTS© 2026 DoseRank · Evidence-based supplements
Methodology·Outcomes·Categories
DOSERANKEVIDENCE-BASED SUPPLEMENTS
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  3. ·Muscle health
  4. ·Muscle mass

Increase muscle mass

View top productsTake the 60-sec quizGet the reportSee methodology

What this outcome means

Muscle mass is how much skeletal muscle your body carries — the tissue that powers movement, lifts loads, and shapes your strength and metabolism. On DoseRank it maps to a defined health outcome built from human studies on lean body mass, muscle cross-sectional area, and grip and strength measures – data sourced from open sources and specialized resources. DoseRank is not medical advice.

Who it's for

Building strengthLifters and athletes working to add lean size and power.
Age-related declineOlder adults losing muscle as the years add up.
Rebuilding after layoffComing back from injury, illness, or long time off training.
Stack buildersAlready taking supplements such as L-Leucine and want the dose right.

Evidence level

92Strong

L-Leucine – has strong public evidence. DoseRank looks at both evidence quality and formula fit. A DoseFit Score of 90 means this product's ingredient forms and doses are close to what was used in the studies behind this ranking - DoseRank weights each product ingredient.

Best ingredients

L-Leucine is the best supported ingredient signal for this outcome.

Dose matchedDoseFit 90

Scores reward products dosed inside or above the studied range, not just the right ingredient. Examples: Below range: L-Leucine 5 g vs 2000-5000 g.

ProcessedProcessedEvery product DoseRank ingested and scored for this outcome, before any availability or relevance filtering.
5.1k
AvailableAvailableOf the products processed, how many are currently in stock and purchasable from a tracked retailer.
5.1k
IngredientsIngredientsNumber of relevant ingredients for this outcome. Each is judged on its own evidence and dose fit score.
10
BrandsBrandsNumber of unique brands represented across the ranked products for this outcome.
493
CoverageCoverageHigher is betterShare of the relevant, in-stock market DoseRank has structured data for. Higher coverage means fewer blind spots in the ranking.
100%

How to read the scores

What every metric means

Each score is 0–100. Higher is better for every metric below.
CompositeThe overall DoseRank score — a weighted blend of clinical strength, evidence, dose fit, trust and value.Higher is better
ClinicalHow strongly the formula's ingredients and doses match what clinical studies used for this outcome.Higher is better
EvidenceHow much published human research backs the formula's key ingredients for this outcome — both how many studies exist and how strong they are.Higher is better
ValueHow the price per serving compares with similar products for this outcome — 50 is the typical price, higher means better value for your money.Higher is better
TrustHow well customers rate this product, with extra weight given to ratings backed by a large number of reviews.Higher is better
PopularityHow strongly this product sells compared with the other ranked products for this outcome.Higher is better

This legend covers the scores on this page — for data sources, scoring weights, and limits, read the full methodology →

Not sure which is right for you?

Answer a few questions about your goals, habits, stack, and budget. Then, DoseRank will find the products that best match your needs based on your answers. It's free and only takes 60 seconds! No account is required.

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Get a personal report

A saved, shareable breakdown: your matched products, dose math, interaction flags to discuss with a clinician, and a price-tracked stack you can revisit.

Questions

Frequently asked

Each product gets a composite score blending clinical strength, evidence, dose fit, trust and value. The #1 on the DoseRank tab has the highest composite; the other tabs re-rank the same products by Value, Trust, or Popularity. Placement is never paid.

DoseRank is not medical advice. Scores summarize publicly available product and study data to help you compare options; they are not a diagnosis or a treatment recommendation. If you are pregnant, breastfeeding, taking medication, or managing a health condition, consult a qualified clinician before starting any supplement. Retailer links may be affiliate links and DoseRank may earn a commission — rankings and placement are determined by the scoring model only, never by payment from a brand. Statements about supplements have not been evaluated by the FDA. Products are not intended to diagnose, treat, cure, or prevent any disease.

Relevant ingredients

Which ingredient types matter for muscle massOpen to see which ingredient types matter for muscle mass

4.4k products across 1 ingredient types — open to filter the ranking.
Use types to filter ranked products

Amino Acids & Derivatives

4.4k products

The building blocks of protein, taken singly for targeted effects – leucine for muscle, theanine for calm. Free-form versions absorb fast on an empty stomach.

Typical: ,

Top decision cards

Best products for muscle mass

Ranking by · Composite outcome score

Best overall — the composite outcome score.

Top pick · DoseRank

Why this ranks #1 for muscle mass

#1

Nutricost, L-Leucine, Unflavored, 17.9 oz (500 g)

Nutricost$0.20 / serving4.7 · 363Available now

Why this ranks here

  • Evidence fitL-Leucine is the strongest evidence signal for this outcome.
  • Dose fitL-Leucine at 5 g sits below the studied 2000-5000 mg window.
  • Price / serving$0.20 per serving — low price tier for this outcome.
  • AvailabilityIn stock across major retailers; 99% availability confidence.
  • TrustMixed trust signals — ratings are positive but the base is limited.

Trade-offs

Trust signals sit below the other picks

The numbers

83
87
90
89

5 gBelow rangebelow the studied 2000-5000 mg window
Compare top 3Product dataOpen at retailer

The rest of the ranking · DoseRank

Top 10 ranked products
#ProductPrice

Keep exploring

Related outcomes

Muscle crampsPainful involuntary muscle contractions.Muscle strengthAbility of muscles to generate force.Muscle weaknessReduced ability to generate force.Sarcopenia statusPresence of low muscle mass and function.
Last updated Jun 12, 2026

DoseRank is not medical advice. Scores summarize publicly available product and study data to help you compare options; they are not a diagnosis or a treatment recommendation. If you are pregnant, breastfeeding, taking medication, or managing a health condition, consult a qualified clinician before starting any supplement. Retailer links may be affiliate links and DoseRank may earn a commission — rankings and placement are determined by the scoring model only, never by payment from a brand. Statements about supplements have not been evaluated by the FDA. Products are not intended to diagnose, treat, cure, or prevent any disease.

Comparison preview

Compare the top 3, side by side

Sign-in to see all metrics

The top three for the current view — free to read, no account. Saving, exporting, alerts and the full filter set unlock once you sign in or build a personal report.

Metric
#1Nutricost, L-Leucine, Unflavored, 17.9 oz (500 g)Nutricost · $0.20/serving
#2MuscleMeds, Carnivor Beef Aminos, 100% Pure Beef Protein, 300 TabletsMuscleMeds · $0.22/serving
#3California Gold Nutrition, Instantized BCAA Powder with L-Leucine, L-Isoleucine, and L-Valine, Unflavored, 2 lb (907 g)California Gold Nutrition · $0.14/serving
Composite838382
Clinical878685
Dose fit908471
Value898892
Popularity807583
Key dosages & price · raw values
5 gHighest—2.5 g
—8511 mgHighest—
—4253 mgHighest—
Rating
Number of ratings
Price
Price per serving
Serving size
Trust

See more metrics for every product.

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Unlocks with accountFull list of ingredients and dosagesFull list of metricsPrice-drop alertsRanking-changes alertsPersistent stack