DOSERANKEVIDENCE-BASED SUPPLEMENTS
DOSERANKEVIDENCE-BASED SUPPLEMENTS© 2026 DoseRank · Evidence-based supplements
Methodology·Outcomes·Categories
DOSERANKEVIDENCE-BASED SUPPLEMENTS
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  2. ·Outcomes
  3. ·Antioxidant status
  4. ·Antioxidant capacity

Increase antioxidant capacity

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What this outcome means

Antioxidant capacity is your body's measured ability to neutralize reactive molecules and keep oxidative stress in check. On DoseRank it maps to a defined health outcome built from human studies on total antioxidant capacity assays, oxidative stress markers, and lipid peroxidation levels – data sourced from open sources and specialized resources. DoseRank is not medical advice.

Who it's for

High oxidative loadHeavy training, pollution, or smoking that raises oxidative stress.
Metabolically stressedConditions where reactive molecules outpace the body's defenses.
Prevention-mindedPeople tracking oxidative markers as part of long-term health.
Stack buildersAlready taking supplements such as Ascorbic Acid or Selenomethionine and want the dose right.

Evidence level

85Strong

Selenomethionine – has strong public evidence, and Ascorbic Acid adds supporting evidence. DoseRank looks at both evidence quality and formula fit. A DoseFit Score of 67 means this product's ingredient forms and doses are close to what was used in the studies behind this ranking - DoseRank weights each product ingredient.

Best ingredients

Selenomethionine leads this outcome, supported by Ascorbic Acid.

Dose partly matchedDoseFit 67

Scores reward products dosed inside or above the studied range, not just the right ingredient. Examples: In range: Ascorbic Acid 500 mg vs 500-1000 mg, Selenomethionine 50 mcg vs 50-200 mcg.

ProcessedProcessedEvery product DoseRank ingested and scored for this outcome, before any availability or relevance filtering.
12.6k
AvailableAvailableOf the products processed, how many are currently in stock and purchasable from a tracked retailer.
12.6k
IngredientsIngredientsNumber of relevant ingredients for this outcome. Each is judged on its own evidence and dose fit score.
120
BrandsBrandsNumber of unique brands represented across the ranked products for this outcome.
597
CoverageCoverageHigher is betterShare of the relevant, in-stock market DoseRank has structured data for. Higher coverage means fewer blind spots in the ranking.
100%

How to read the scores

What every metric means

Each score is 0–100. Higher is better for every metric below.
CompositeThe overall DoseRank score — a weighted blend of clinical strength, evidence, dose fit, trust and value.Higher is better
ClinicalHow strongly the formula's ingredients and doses match what clinical studies used for this outcome.Higher is better
EvidenceHow much published human research backs the formula's key ingredients for this outcome — both how many studies exist and how strong they are.Higher is better
ValueHow the price per serving compares with similar products for this outcome — 50 is the typical price, higher means better value for your money.Higher is better
TrustHow well customers rate this product, with extra weight given to ratings backed by a large number of reviews.Higher is better
PopularityHow strongly this product sells compared with the other ranked products for this outcome.Higher is better

This legend covers the scores on this page — for data sources, scoring weights, and limits, read the full methodology →

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A saved, shareable breakdown: your matched products, dose math, interaction flags to discuss with a clinician, and a price-tracked stack you can revisit.

Questions

Frequently asked

Each product gets a composite score blending clinical strength, evidence, dose fit, trust and value. The #1 on the DoseRank tab has the highest composite; the other tabs re-rank the same products by Value, Trust, or Popularity. Placement is never paid.

DoseRank is not medical advice. Scores summarize publicly available product and study data to help you compare options; they are not a diagnosis or a treatment recommendation. If you are pregnant, breastfeeding, taking medication, or managing a health condition, consult a qualified clinician before starting any supplement. Retailer links may be affiliate links and DoseRank may earn a commission — rankings and placement are determined by the scoring model only, never by payment from a brand. Statements about supplements have not been evaluated by the FDA. Products are not intended to diagnose, treat, cure, or prevent any disease.

Relevant ingredients

Which ingredient types matter for antioxidant capacityOpen to see which ingredient types matter for antioxidant capacity

19.3k products across 8 ingredient types — open to filter the ranking.
Use types to filter ranked products

Antioxidants & Bioactive Compounds

4.2k products

Molecules that neutralize free radicals and tune cell signaling. Helpful in balance; mega-doses can blunt the body's own adaptive defenses.

Typical: , , , ...

Vitamins

5.1k products

Essential micronutrients the body can't make in sufficient amounts. Fat-soluble ones (A, D, E, K) store up; water-soluble ones need regular topping-up.

Typical: , , , ...

Amino Acids & Derivatives

1.2k products

The building blocks of protein, taken singly for targeted effects – leucine for muscle, theanine for calm. Free-form versions absorb fast on an empty stomach.

Typical: , ,

Minerals & Trace Elements

2.5k products

Inorganic nutrients from calcium to zinc. The chemical form drives absorption – chelates and citrates usually beat cheap oxides.

Typical: , , , ...

Botanicals/Herbal Extracts

5.4k products

Concentrated plant and herbal extracts standardized to actives. Potency depends on the extract ratio and marker content, not raw weight.

Typical: , , , ...

Enzymes

41 products

Proteins that speed specific reactions, from digesting food to thinning fibrin. Taken with meals for digestion or away from food for systemic effects.

Typical:

Hormones & Hormone-like Compounds

618 products

Compounds that signal like the body's own hormones — melatonin, DHEA, pregnenolone. Powerful at tiny doses and easy to overdo; timing matters more than potency.

Typical:

Glandulars & Animal-Derived Extracts

124 products

Animal gland and organ-tissue extracts used traditionally for targeted organ support. Purity and grass-fed sourcing are the key quality markers.

Top decision cards

Best products for antioxidant capacity

Ranking by · Composite outcome score

Best overall — the composite outcome score.

Top pick · DoseRank

Why this ranks #1 for antioxidant capacity

#1

California Gold Nutrition, Defender 4, with Vitamin C, Vitamin D, Zinc & Selenium, 180 Veggie Capsules

California Gold Nutrition$0.07 / serving4.7 · 186,915Available now

Why this ranks here

  • Evidence fitSelenomethionine leads the evidence here, backed by Ascorbic Acid.
  • Dose fit2 of 2 dosed ingredients land in the studied range. Ascorbic Acid at 500 mg lands inside the studied 500-1000 mg window.
  • Price / serving$0.07 per serving — low price tier for this outcome.
  • AvailabilityIn stock across major retailers; 99% availability confidence.
  • TrustStrong trust signals — consistently high marks from verified buyer ratings.

Trade-offs

Dose fit is the weak spot on this listEvidence depth trails the rest of this list

The numbers

94
96
67
88

500 mgIn rangeinside the studied 500-1000 mg window
50 mcgIn rangeinside the studied 50-200 µg window
Compare top 3Product dataOpen at retailer

The rest of the ranking · DoseRank

Top 10 ranked products
#ProductPrice
Last updated Jun 16, 2026

DoseRank is not medical advice. Scores summarize publicly available product and study data to help you compare options; they are not a diagnosis or a treatment recommendation. If you are pregnant, breastfeeding, taking medication, or managing a health condition, consult a qualified clinician before starting any supplement. Retailer links may be affiliate links and DoseRank may earn a commission — rankings and placement are determined by the scoring model only, never by payment from a brand. Statements about supplements have not been evaluated by the FDA. Products are not intended to diagnose, treat, cure, or prevent any disease.

Comparison preview

Compare the top 3, side by side

Sign-in to see all metrics

The top three for the current view — free to read, no account. Saving, exporting, alerts and the full filter set unlock once you sign in or build a personal report.

Metric
#1California Gold Nutrition, Defender 4, with Vitamin C, Vitamin D, Zinc & Selenium, 180 Veggie CapsulesCalifornia Gold Nutrition · $0.07/serving
#2Life Extension, Super Selenium Complex & Vitamin E, 100 Vegetarian CapsulesLife Extension · $0.09/serving
#3Centrum, Men Multivitamin, 120 TabletsCentrum · $0.12/serving
Composite949493
Clinical969695
Dose fit676771
Value888481
Popularity969998
Key dosages & price · raw values
500 mgHighest——
50 mcgHighest50 mcgHighest—
——1050 mcgHighest
Rating
Number of ratings
Price
Price per serving
Serving size
Trust

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Unlocks with accountFull list of ingredients and dosagesFull list of metricsPrice-drop alertsRanking-changes alertsPersistent stack