Is a higher dose always better?

No. Dose-fit rewards landing inside the range studied for the outcome — over-dosing (common with melatonin) or under-dosing both lower the score. The goal is the effective dose, not the biggest number.

What does the Value score mean?

The Value score compares a product's price per serving with clinically relevant products ranked for the same outcome. A score of 50 is the typical price; above 50 means better value than typical, while below 50 means the product costs more than typical. It is a 0–100 value signal, not a percentile.

Why is the cheapest product not #1?

Cost is only one input. The cheapest pick here is a citrate form with weaker absorption and a stock-risk flag, so it leads on Value-for-cost but trails on the composite that also weighs evidence, dose fit and availability.

Are these affiliate links?

Retailer links may be affiliate links and DoseRank may earn a commission. Rankings and placement are determined by the scoring model only — never by payment from a brand.

Is this medical advice?

No. DoseRank summarizes evidence to help you choose; it is not a substitute for a clinician, especially if you are pregnant, breastfeeding, on medication, or managing a health condition.

Reduce sarcopenia

What this outcome means

Sarcopenia status reflects whether muscle mass and strength have declined enough to affect how you move and function. On DoseRank it maps to a defined health outcome built from human studies on muscle mass measures, grip strength, and gait speed – data sourced from open sources and specialized resources. DoseRank is not medical advice.

Who it's for

Aging muscleOlder adults noticing weaker, smaller muscles year over year.

Weak gripPeople struggling with strength tasks like carrying or rising from a chair.

Slowing mobilityThose whose walking pace and steadiness have gradually declined.

Stack buildersAlready taking supplements such as L-Leucine and want the dose right.

Evidence level

92Strong

L-Leucine – has strong public evidence. DoseRank looks at both evidence quality and formula fit. A DoseFit Score of 82 means this product's ingredient forms and doses are close to what was used in the studies behind this ranking - DoseRank weights each product ingredient.

Best ingredients

L-Leucine is the best supported ingredient signal for this outcome.

Dose matchedDoseFit 82

Scores reward products dosed inside or above the studied range, not just the right ingredient. Examples: In range: L-Leucine 5 g vs 3-6 g.

Processed

1.1k

Available

1.1k

Ingredients

Brands

158

Coverage

100%

How to read the scores

What every metric means

Each score is 0–100. Higher is better for every metric below.

CompositeThe overall DoseRank score — a weighted blend of clinical strength, evidence, dose fit, trust and value.Higher is better

ClinicalHow strongly the formula's ingredients and doses match what clinical studies used for this outcome.Higher is better

EvidenceHow much published human research backs the formula's key ingredients for this outcome — both how many studies exist and how strong they are.Higher is better

ValueHow the price per serving compares with similar products for this outcome — 50 is the typical price, higher means better value for your money.Higher is better

TrustHow well customers rate this product, with extra weight given to ratings backed by a large number of reviews.Higher is better

PopularityHow strongly this product sells compared with the other ranked products for this outcome.Higher is better

This legend covers the scores on this page — for data sources, scoring weights, and limits, read the full methodology →

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Get a personal report

A saved, shareable breakdown: your matched products, dose math, interaction flags to discuss with a clinician, and a price-tracked stack you can revisit.

Questions

Frequently asked

Each product gets a composite score blending clinical strength, evidence, dose fit, trust and value. The #1 on the DoseRank tab has the highest composite; the other tabs re-rank the same products by Value, Trust, or Popularity. Placement is never paid.

Reduce sarcopenia

What this outcome means

Who it's for

Aging muscleOlder adults noticing weaker, smaller muscles year over year.

Weak gripPeople struggling with strength tasks like carrying or rising from a chair.

Slowing mobilityThose whose walking pace and steadiness have gradually declined.

Stack buildersAlready taking supplements such as L-Leucine and want the dose right.

Evidence level

92Strong

Best ingredients

L-Leucine is the best supported ingredient signal for this outcome.

Dose matchedDoseFit 82

Scores reward products dosed inside or above the studied range, not just the right ingredient. Examples: In range: L-Leucine 5 g vs 3-6 g.

Processed

1.1k

Available

1.1k

Ingredients

Brands

158

Coverage

100%

Relevant ingredients

Which ingredient types matter for sarcopenia statusOpen to see which ingredient types matter for sarcopenia status

848 products across 1 ingredient types — open to filter the ranking.

Use types to filter ranked products

Amino Acids & Derivatives

848 products

The building blocks of protein, taken singly for targeted effects – leucine for muscle, theanine for calm. Free-form versions absorb fast on an empty stomach.

Typical: ,

Top decision cards

Best products for sarcopenia status

Ranking by · Composite outcome score

Best overall — the composite outcome score.

Top pick · DoseRank

Why this ranks #1 for sarcopenia status

Nutricost, L-Leucine, Unflavored, 17.9 oz (500 g)

Nutricost$0.20 / serving4.7 · 378Available now

Also helps with

Muscle mass

Why this ranks here

Evidence fitL-Leucine is the strongest evidence signal for this outcome.
Dose fitL-Leucine at 5 g lands inside the studied 3-6 g window.
Price / serving$0.20 per serving — low price tier for this outcome.
AvailabilityIn stock across major retailers; 99% availability confidence.
TrustMixed trust signals — ratings are positive but the base is limited.

The numbers

5 gIn rangeinside the studied 3-6 g window

Compare top 3 Product data Open at retailer

The rest of the ranking · DoseRank

Top 10 ranked products

MuscleMeds, Carnivor Beef Aminos, 100% Pure Beef Protein, 300 Tablets

MuscleMedsClinical87Dose fit76Popularity76$0.22/ serving

ALLMAX, Essentials, EAA, 11.29 oz (320 g)

ALLMAXClinical88Dose fit75Popularity80$0.70/ serving

ALLMAX, Essentials, Leucine+, 14.11 oz (400 g)

ALLMAXClinical88Dose fit82Popularity50$0.34/ serving

XTEND, 7G BCAA, Lemon-Lime Squeeze, 2.68 lbs (1.22 kg)

XTENDClinical86Dose fit71Popularity68$0.65/ serving

XTEND, 7G BCAA, Mango Madness, 14.3 oz (405 g)

XTENDClinical86Dose fit71Popularity80$0.84/ serving

XTEND, 7G BCAA, Lemon-Lime Squeeze, 14.3 oz (405 g)

XTENDClinical86Dose fit71Popularity76$0.84/ serving

XTEND, 7G BCAA, Mango Madness, 2.68 lb (1.215 kg)

XTENDClinical86Dose fit71Popularity50$0.65/ serving

XTEND, 7G BCAA, Glacial Grape, 13.8 oz (390 g)

XTENDClinical86Dose fit71Popularity68$0.84/ serving

XTEND, 7G BCAA, Glacial Grape, 2.58 lbs (1.17 kg)