DOSERANKEVIDENCE-BASED SUPPLEMENTS
DOSERANKEVIDENCE-BASED SUPPLEMENTS© 2026 DoseRank · Evidence-based supplements
Methodology·Outcomes·Categories·Blog
Support·Feedback
DOSERANKEVIDENCE-BASED SUPPLEMENTS
Stack
  1. Search
  2. ·Outcomes
  3. ·Skin symptoms
  4. ·Psoriasis severity

Reduce psoriasis symptoms

View top productsTake the 60-sec quizGet the reportSee methodology

What this outcome means

Psoriasis severity describes how widespread and inflamed psoriatic skin patches are, from a few small plaques to large, scaly, irritated areas. On DoseRank it maps to a defined health outcome built from human studies on PASI scores, plaque coverage, and lesion redness and scaling – data sourced from open sources and specialized resources. DoseRank is not medical advice.

Who it's for

Flare-prone skinPatches that worsen in cycles of redness, scaling, and itch.
Widespread plaquesLesions covering larger areas of the body and scalp.
Stubborn patchesPersistent lesions that linger despite ongoing skin care.
Stack buildersAlready taking supplements such as Oregon Grape and want the dose right.

Evidence level

78Moderate-strong

Oregon Grape – has moderate public evidence for this outcome. This usually means there are smaller or mechanistic studies, but not randomized human trials. A DoseFit Score of 67 means this product's ingredient forms and doses are close to what was used in the studies behind this ranking - DoseRank weights each product ingredient.

Best available ingredients

Oregon Grape is the best supported ingredient signal for this outcome.

Dose partly matchedDoseFit 67

Scores reward products dosed inside or above the studied range, not just the right ingredient. Examples: In range: Oregon Grape 500 mg vs 500-1500 mg.

ProcessedProcessedEvery product DoseRank ingested and scored for this outcome, before any availability or relevance filtering.
26
AvailableAvailableOf the products processed, how many are currently in stock and purchasable from a tracked retailer.
26
IngredientsIngredientsNumber of relevant ingredients for this outcome. Each is judged on its own evidence and dose fit score.
1
BrandsBrandsNumber of unique brands represented across the ranked products for this outcome.
14
CoverageCoverageHigher is betterShare of the relevant, in-stock market DoseRank has structured data for. Higher coverage means fewer blind spots in the ranking.
100%

How to read the scores

What every metric means

Each score is 0–100. Higher is better for every metric below.
CompositeThe overall DoseRank score — a weighted blend of clinical strength, evidence, dose fit, trust and value.Higher is better
ClinicalHow strongly the formula's ingredients and doses match what clinical studies used for this outcome.Higher is better
EvidenceHow much published human research backs the formula's key ingredients for this outcome — both how many studies exist and how strong they are.Higher is better
ValueHow the price per serving compares with similar products for this outcome — 50 is the typical price, higher means better value for your money.Higher is better
TrustHow well customers rate this product, with extra weight given to ratings backed by a large number of reviews.Higher is better
PopularityHow strongly this product sells compared with the other ranked products for this outcome.Higher is better

This legend covers the scores on this page — for data sources, scoring weights, and limits, read the full methodology →

Not sure which is right for you?

Answer a few questions about your goals, habits, stack, and budget. Then, DoseRank will find the products that best match your needs based on your answers. It's free and only takes 60 seconds! No account is required.

Take 60-sec quiz

Get a personal report

A saved, shareable breakdown: your matched products, dose math, interaction flags to discuss with a clinician, and a price-tracked stack you can revisit.

Questions

Frequently asked

Each product gets a composite score blending clinical strength, evidence, dose fit, trust and value. The #1 on the DoseRank tab has the highest composite; the other tabs re-rank the same products by Value, Trust, or Popularity. Placement is never paid.

No. Dose-fit rewards landing inside the range studied for the outcome — over-dosing (common with melatonin) or under-dosing both lower the score. The goal is the effective dose, not the biggest number.

The Value score compares a product's price per serving with clinically relevant products ranked for the same outcome. A score of 50 is the typical price; above 50 means better value than typical, while below 50 means the product costs more than typical. It is a 0–100 value signal, not a percentile.

Cost is only one input. The cheapest pick here is a citrate form with weaker absorption and a stock-risk flag, so it leads on Value-for-cost but trails on the composite that also weighs evidence, dose fit and availability.

Retailer links may be affiliate links and DoseRank may earn a commission. Rankings and placement are determined by the scoring model only — never by payment from a brand.

No. DoseRank summarizes evidence to help you choose; it is not a substitute for a clinician, especially if you are pregnant, breastfeeding, on medication, or managing a health condition.

DoseRank is not medical advice. Scores summarize publicly available product and study data to help you compare options; they are not a diagnosis or a treatment recommendation. If you are pregnant, breastfeeding, taking medication, or managing a health condition, consult a qualified clinician before starting any supplement. Retailer links may be affiliate links and DoseRank may earn a commission — rankings and placement are determined by the scoring model only, never by payment from a brand. Statements about supplements have not been evaluated by the FDA. Products are not intended to diagnose, treat, cure, or prevent any disease.

Relevant ingredients

Which ingredient types matter for psoriasis severityOpen to see which ingredient types matter for psoriasis severity

20 products across 1 ingredient types — open to filter the ranking.
Use types to filter ranked products

Botanicals/Herbal Extracts

20 products

Concentrated plant and herbal extracts standardized to actives. Potency depends on the extract ratio and marker content, not raw weight.

Typical:

Top decision cards

Best products for psoriasis severity

Ranking by · Composite outcome score

Best overall — the composite outcome score.

Top pick · DoseRank

Why this ranks #1 for psoriasis severity

#1

Nature's Way, Oregon Grape, 500 mg, 90 Vegan Capsules

Nature's Way$0.07 / serving4.5 · 488Available now

Why this ranks here

  • Evidence fitOregon Grape has moderate human evidence for this outcome.
  • Dose fitOregon Grape at 500 mg lands inside the studied 500-1500 mg window.
  • Price / serving$0.07 per serving — mid price tier for this outcome.
  • AvailabilityIn stock across major retailers; 99% availability confidence.
  • TrustMixed trust signals — ratings are positive but the base is limited.

The numbers

79
85
67
77

500 mgIn rangeinside the studied 500-1500 mg window
Compare top 3Product dataOpen at retailer

The rest of the ranking · DoseRank

Top 10 ranked products
#ProductPrice
2

Oregon's Wild Harvest, Organic Oregon Grape, 90 Organic Vegan Capsules (380 mg per Capsule)

Oregon's Wild Harvest
Clinical87Dose fit82Popularity30$0.72/ serving
3

Solaray, True Herbs, Oregon Grape, 400 mg, 100 VegCaps

Solaray
Clinical61Dose fit27Popularity30$0.14/ serving
4

Solaray, Berberine with Oregon Grape, 60 VegCaps

Solaray
Clinical27Dose fit7Popularity76$0.36/ serving
5

Buried Treasure, Liquid Advantage, ACF Immune Support, 16.54 fl oz (496 ml)

Buried Treasure
Clinical10Dose fit2Popularity30$1.71/ serving
6

Eclectic Herb, Vita Biotic, Supports Immunity, 150 Veg Caps

Eclectic Herb
Clinical8Dose fit1Popularity30$0.79/ serving
7

Plnt, Liver Support, 90 Vegetarian Capsules

Plnt
Clinical1Dose fit0Popularity30$0.24/ serving
8

Source Naturals, Inflama-Rest™, 60 Tablets

Source Naturals
Clinical1Dose fit0Popularity30$1.22/ serving
9

Source Naturals, Liver Guard™, 120 Tablets

Source Naturals
Clinical0Dose fit0Popularity30$0.57/ serving
10

Source Naturals, Liver Guard™, Silymarin, CoQ10, N-Acetyl Cysteine Complex, 60 Tablets

Source Naturals
Clinical0Dose fit0Popularity30$0.59/ serving

Keep exploring

Related outcomes

Acne severityExtent or intensity of acne lesions.Atopic dermatitis symptomsItching, rash, and inflammation related to eczema.Eczema severityOverall clinical burden of eczema.
Last updated Aug 20, 2026

DoseRank is not medical advice. Scores summarize publicly available product and study data to help you compare options; they are not a diagnosis or a treatment recommendation. If you are pregnant, breastfeeding, taking medication, or managing a health condition, consult a qualified clinician before starting any supplement. Retailer links may be affiliate links and DoseRank may earn a commission — rankings and placement are determined by the scoring model only, never by payment from a brand. Statements about supplements have not been evaluated by the FDA. Products are not intended to diagnose, treat, cure, or prevent any disease.

Comparison preview

Compare the top 3, side by side

Sign-in to see all metrics

The top three for the current view — free to read, no account. Saving, exporting, alerts and the full filter set unlock once you sign in or build a personal report.

Metric
#1Nature's Way, Oregon Grape, 500 mg, 90 Vegan CapsulesNature's Way · $0.07/serving
#2Oregon's Wild Harvest, Organic Oregon Grape, 90 Organic Vegan Capsules (380 mg per Capsule)Oregon's Wild Harvest · $0.72/serving
#3Solaray, True Herbs, Oregon Grape, 400 mg, 100 VegCapsSolaray · $0.14/serving
Composite797454
Clinical858761
Dose fit678227
Value772664
Popularity503030
Key dosages & price · raw values
500 mg1140 mgHighest400 mg
Rating
Number of ratings
Price
Price per serving
Serving size
Trust

See more metrics for every product.

Free with an account. No card required.
Unlocks with accountFull list of ingredients and dosagesFull list of metricsPrice-drop alertsRanking-changes alertsPersistent stack