Is a higher dose always better?

No. Dose-fit rewards landing inside the range studied for the outcome — over-dosing (common with melatonin) or under-dosing both lower the score. The goal is the effective dose, not the biggest number.

What does the Value score mean?

The Value score compares a product's price per serving with clinically relevant products ranked for the same outcome. A score of 50 is the typical price; above 50 means better value than typical, while below 50 means the product costs more than typical. It is a 0–100 value signal, not a percentile.

Why is the cheapest product not #1?

Cost is only one input. The cheapest pick here is a citrate form with weaker absorption and a stock-risk flag, so it leads on Value-for-cost but trails on the composite that also weighs evidence, dose fit and availability.

Are these affiliate links?

Retailer links may be affiliate links and DoseRank may earn a commission. Rankings and placement are determined by the scoring model only — never by payment from a brand.

Is this medical advice?

No. DoseRank summarizes evidence to help you choose; it is not a substitute for a clinician, especially if you are pregnant, breastfeeding, on medication, or managing a health condition.

Reduce cancer risk

What this outcome means

Cancer incidence describes how often new cancers are diagnosed in a group of people over a given stretch of time. On DoseRank it maps to a defined health outcome built from human studies on new diagnosis rates, age-adjusted incidence rates, and cancer-specific incidence ratios across populations – data sourced from open sources and specialized resources. DoseRank is not medical advice.

Who it's for

Family-history watchersPeople with close relatives who have faced cancer.

Screening-age adultsThose reaching the age for routine cancer screening checks.

Higher-exposure backgroundsLives shaped by smoking, sun, or occupational exposures.

Stack buildersAlready taking supplements such as Nicotinamide and want the dose right.

Evidence level

92Strong

Nicotinamide – has strong public evidence. DoseRank looks at both evidence quality and formula fit. A DoseFit Score of 67 means this product's ingredient forms and doses are close to what was used in the studies behind this ranking - DoseRank weights each product ingredient.

Best ingredients

Nicotinamide is the best supported ingredient signal for this outcome.

Dose partly matchedDoseFit 67

Scores reward products dosed inside or above the studied range, not just the right ingredient. Examples: In range: Nicotinamide 500 mg vs 500-1000 mg.

Processed

1.9k

Available

1.9k

Ingredients

Brands

208

Coverage

100%

How to read the scores

What every metric means

Each score is 0–100. Higher is better for every metric below.

CompositeThe overall DoseRank score — a weighted blend of clinical strength, evidence, dose fit, trust and value.Higher is better

ClinicalHow strongly the formula's ingredients and doses match what clinical studies used for this outcome.Higher is better

EvidenceHow much published human research backs the formula's key ingredients for this outcome — both how many studies exist and how strong they are.Higher is better

ValueHow the price per serving compares with similar products for this outcome — 50 is the typical price, higher means better value for your money.Higher is better

TrustHow well customers rate this product, with extra weight given to ratings backed by a large number of reviews.Higher is better

PopularityHow strongly this product sells compared with the other ranked products for this outcome.Higher is better

This legend covers the scores on this page — for data sources, scoring weights, and limits, read the full methodology →

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Get a personal report

A saved, shareable breakdown: your matched products, dose math, interaction flags to discuss with a clinician, and a price-tracked stack you can revisit.

Questions

Frequently asked

Each product gets a composite score blending clinical strength, evidence, dose fit, trust and value. The #1 on the DoseRank tab has the highest composite; the other tabs re-rank the same products by Value, Trust, or Popularity. Placement is never paid.

Reduce cancer risk

What this outcome means

Who it's for

Family-history watchersPeople with close relatives who have faced cancer.

Screening-age adultsThose reaching the age for routine cancer screening checks.

Higher-exposure backgroundsLives shaped by smoking, sun, or occupational exposures.

Stack buildersAlready taking supplements such as Nicotinamide and want the dose right.

Evidence level

92Strong

Best ingredients

Nicotinamide is the best supported ingredient signal for this outcome.

Dose partly matchedDoseFit 67

Scores reward products dosed inside or above the studied range, not just the right ingredient. Examples: In range: Nicotinamide 500 mg vs 500-1000 mg.

Processed

1.9k

Available

1.9k

Ingredients

Brands

208

Coverage

100%

Relevant ingredients

Which ingredient types matter for cancer incidenceOpen to see which ingredient types matter for cancer incidence

1.8k products across 1 ingredient types — open to filter the ranking.

Use types to filter ranked products

Vitamins

1.8k products

Essential micronutrients the body can't make in sufficient amounts. Fat-soluble ones (A, D, E, K) store up; water-soluble ones need regular topping-up.

Typical: ,

Top decision cards

Best products for cancer incidence

Ranking by · Composite outcome score

Best overall — the composite outcome score.

Top pick · DoseRank

Why this ranks #1 for cancer incidence

Nature's Craft, Nicotinamide, 500 mg, 240 Capsules

Nature's Craft$0.11 / serving4.7 · 521Available now

Also helps with

Niacin status

Precancerous lesion progression

Acne severity

Why this ranks here

Evidence fitNicotinamide is the strongest evidence signal for this outcome.
Dose fitNicotinamide at 500 mg lands inside the studied 500-1000 mg window.
Price / serving$0.11 per serving — high price tier for this outcome.
AvailabilityIn stock across major retailers; 99% availability confidence.
TrustMixed trust signals — ratings are positive but the base is limited.

The numbers

500 mgIn rangeinside the studied 500-1000 mg window

Compare top 3 Product data Open at retailer

The rest of the ranking · DoseRank

Top 10 ranked products

Nutricost, Lycopene, 50 mg, 120 Softgels

NutricostClinical20Dose fit90Popularity84$0.26/ serving

Vibrant Health, Maximum Vibrance®, Version 7.0, Vanilla Bean, 21.5 oz (610 g)

Vibrant HealthClinical21Dose fit86Popularity30$5.82/ serving

21st Century, Lycopene, 25 mg, 60 Tablets

21st CenturyClinical19Dose fit74Popularity96$0.18/ serving

Pure Essence, DIM-D™, 30 Vegi-Caps

Pure EssenceClinical20Dose fit100Popularity30$0.74/ serving

Nutricost, Lycopene, 20 mg, 120 Softgels

NutricostClinical18Dose fit71Popularity89$0.15/ serving

Futurebiotics, Prost Advance®, 90 Vegetarian Capsules

FuturebioticsClinical20Dose fit92Popularity30$0.63/ serving

Snap Supplements, Prostate Health, 90 Capsules

Snap SupplementsClinical20Dose fit96Popularity50$1.26/ serving

Swanson Vitamins, Lycopene, 20 mg, 60 Softgels

Swanson VitaminsClinical18Dose fit71Popularity89$0.26/ serving

Solaray, Spectro™ Multivitamin, Man, 120 Capsules

SolarayClinical20Dose fit92Popularity30$1.02/ serving