DOSERANKEVIDENCE-BASED SUPPLEMENTS
DOSERANKEVIDENCE-BASED SUPPLEMENTS© 2026 DoseRank · Evidence-based supplements
Methodology·Outcomes·Categories
DOSERANKEVIDENCE-BASED SUPPLEMENTS
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  3. ·Folate status
  4. ·Folate status

Improve folate status

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What this outcome means

Folate status is whether your body holds enough folate, a nutrient your cells rely on to build blood, tissue, and DNA. On DoseRank it maps to a defined health outcome built from human studies on serum and red-cell folate levels, folate concentration, and sufficiency thresholds – data sourced from open sources and specialized resources. DoseRank is not medical advice.

Who it's for

Planning pregnancyWomen preparing to conceive who want folate reserves topped up.
Low folate labsPeople flagged with folate readings below the sufficient range.
Limited-diet eatersThose eating few leafy greens and watching folate intake.
Stack buildersAlready taking supplements such as L-Methylfolate and want the dose right.

Evidence level

92Strong

L-Methylfolate – has strong public evidence. DoseRank looks at both evidence quality and formula fit. A DoseFit Score of 78 means this product's ingredient forms and doses are close to what was used in the studies behind this ranking - DoseRank weights each product ingredient.

Best ingredients

L-Methylfolate is the best supported ingredient signal for this outcome.

Dose matchedDoseFit 78

Scores reward products dosed inside or above the studied range, not just the right ingredient. Examples: In range: L-Methylfolate 680 mcg vs 400-1000 mcg.

ProcessedProcessedEvery product DoseRank ingested and scored for this outcome, before any availability or relevance filtering.
3.1k
AvailableAvailableOf the products processed, how many are currently in stock and purchasable from a tracked retailer.
3.1k
IngredientsIngredientsNumber of relevant ingredients for this outcome. Each is judged on its own evidence and dose fit score.
8
BrandsBrandsNumber of unique brands represented across the ranked products for this outcome.
324
CoverageCoverageHigher is betterShare of the relevant, in-stock market DoseRank has structured data for. Higher coverage means fewer blind spots in the ranking.
100%

How to read the scores

What every metric means

Each score is 0–100. Higher is better for every metric below.
CompositeThe overall DoseRank score — a weighted blend of clinical strength, evidence, dose fit, trust and value.Higher is better
ClinicalHow strongly the formula's ingredients and doses match what clinical studies used for this outcome.Higher is better
EvidenceHow much published human research backs the formula's key ingredients for this outcome — both how many studies exist and how strong they are.Higher is better
ValueHow the price per serving compares with similar products for this outcome — 50 is the typical price, higher means better value for your money.Higher is better
TrustHow well customers rate this product, with extra weight given to ratings backed by a large number of reviews.Higher is better
PopularityHow strongly this product sells compared with the other ranked products for this outcome.Higher is better

This legend covers the scores on this page — for data sources, scoring weights, and limits, read the full methodology →

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A saved, shareable breakdown: your matched products, dose math, interaction flags to discuss with a clinician, and a price-tracked stack you can revisit.

Questions

Frequently asked

Each product gets a composite score blending clinical strength, evidence, dose fit, trust and value. The #1 on the DoseRank tab has the highest composite; the other tabs re-rank the same products by Value, Trust, or Popularity. Placement is never paid.

DoseRank is not medical advice. Scores summarize publicly available product and study data to help you compare options; they are not a diagnosis or a treatment recommendation. If you are pregnant, breastfeeding, taking medication, or managing a health condition, consult a qualified clinician before starting any supplement. Retailer links may be affiliate links and DoseRank may earn a commission — rankings and placement are determined by the scoring model only, never by payment from a brand. Statements about supplements have not been evaluated by the FDA. Products are not intended to diagnose, treat, cure, or prevent any disease.

Relevant ingredients

Which ingredient types matter for folate statusOpen to see which ingredient types matter for folate status

3k products across 1 ingredient types — open to filter the ranking.
Use types to filter ranked products

Vitamins

3k products

Essential micronutrients the body can't make in sufficient amounts. Fat-soluble ones (A, D, E, K) store up; water-soluble ones need regular topping-up.

Typical: , , , ...

Last updated Jun 12, 2026

DoseRank is not medical advice. Scores summarize publicly available product and study data to help you compare options; they are not a diagnosis or a treatment recommendation. If you are pregnant, breastfeeding, taking medication, or managing a health condition, consult a qualified clinician before starting any supplement. Retailer links may be affiliate links and DoseRank may earn a commission — rankings and placement are determined by the scoring model only, never by payment from a brand. Statements about supplements have not been evaluated by the FDA. Products are not intended to diagnose, treat, cure, or prevent any disease.

Top decision cards

Best products for folate status

Ranking by · Composite outcome score

Best overall — the composite outcome score.

Top pick · DoseRank

Why this ranks #1 for folate status

#1

Life Extension, BioActive Folate & Vitamin B12, 90 Vegetarian Capsules

Life Extension$0.09 / serving4.8 · 8,042Available now

Why this ranks here

  • Evidence fitL-Methylfolate is the strongest evidence signal for this outcome.
  • Dose fitL-Methylfolate at 680 mcg lands inside the studied 400-1000 µg window.
  • Price / serving$0.09 per serving — low price tier for this outcome.
  • AvailabilityIn stock across major retailers; 99% availability confidence.
  • TrustStrong trust signals — consistently high marks from verified buyer ratings.

Trade-offs

Evidence depth trails the rest of this list

The numbers

88
89
78
86

680 mcgIn rangeinside the studied 400-1000 µg window
Compare top 3Product dataOpen at retailer

The rest of the ranking · DoseRank

Top 10 ranked products
#ProductPrice

Comparison preview

Compare the top 3, side by side

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The top three for the current view — free to read, no account. Saving, exporting, alerts and the full filter set unlock once you sign in or build a personal report.

Metric
#1Life Extension, BioActive Folate & Vitamin B12, 90 Vegetarian CapsulesLife Extension · $0.09/serving
#2Life Extension, Optimized Folate, 1,700 mcg DFE, 100 Vegetarian TabletsLife Extension · $0.10/serving
#3NOW Foods, Methyl Folate, 1,000 mcg, 90 TabletsNOW Foods · $0.14/serving
Composite888787
Clinical898989
Dose fit789292
Value868479
Popularity989699
Key dosages & price · raw values
680 mcgHighest——
Rating
Number of ratings
Price
Price per serving
Serving size
Trust

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