How does DoseRank decide what ranks #1?

Each product gets a composite score blending clinical strength, evidence, dose fit, trust and value. The #1 on the DoseRank tab has the highest composite; the other tabs re-rank the same products by Value, Trust, or Popularity. Placement is never paid.

Is a higher dose always better?

No. Dose-fit rewards landing inside the range studied for the outcome — over-dosing (common with melatonin) or under-dosing both lower the score. The goal is the effective dose, not the biggest number.

What does the Value score mean?

The Value score compares a product's price per serving with clinically relevant products ranked for the same outcome. A score of 50 is the typical price; above 50 means better value than typical, while below 50 means the product costs more than typical. It is a 0–100 value signal, not a percentile.

Why is the cheapest product not #1?

Cost is only one input. The cheapest pick here is a citrate form with weaker absorption and a stock-risk flag, so it leads on Value-for-cost but trails on the composite that also weighs evidence, dose fit and availability.

Are these affiliate links?

Retailer links may be affiliate links and DoseRank may earn a commission. Rankings and placement are determined by the scoring model only — never by payment from a brand.

Is this medical advice?

No. DoseRank summarizes evidence to help you choose; it is not a substitute for a clinician, especially if you are pregnant, breastfeeding, on medication, or managing a health condition.

DOSERANKEVIDENCE-BASED SUPPLEMENTS

Improve niacin status

DOSERANKEVIDENCE-BASED SUPPLEMENTS

Best Supplements for Niacin status — 2758 Ranked | DOSERANK

Top decision cards

Best products for niacin status

Ranking by · Composite outcome score

Best overall — the composite outcome score.

Top pick · DoseRank

Why this ranks #1 for niacin status

21st Century, Niacinamide, Prolonged Release , 110 Tablets

21st Century$0.05 / serving4.6 · 4,534Available now

Also helps with

Precancerous lesion progression

Skin barrier function

Why this ranks here

Evidence fitNiacinamide is the strongest evidence signal for this outcome.
Dose fitNiacinamide at 500 mg lands inside the studied 15-500 mg window.
Price / serving$0.05 per serving — low price tier for this outcome.
AvailabilityIn stock across major retailers; 99% availability confidence.
TrustStrong trust signals — consistently high marks from verified buyer ratings.

The numbers

500 mgIn rangeinside the studied 15-500 mg window

160 mg

Compare top 3 Product data Open at retailer

The rest of the ranking · DoseRank

Top 10 ranked products

NOW Foods, Niacinamide, 500 mg, 100 Veg Capsules

NOW FoodsClinical89Dose fit90Popularity99$0.08/ serving

Life Extension, Vitamin B3 Niacin, 500 mg, 100 Capsules

Life ExtensionClinical89Dose fit90Popularity96$0.05/ serving

NOW Foods, Niacin, 500 mg, 100 Veg Capsules

NOW FoodsClinical89Dose fit90Popularity96$0.07/ serving

Solaray, Niacinamide, 500 mg, 100 VegCaps

SolarayClinical89Dose fit90Popularity91$0.10/ serving

21st Century, B-Complex plus Vitamin C, 100 Tablets

21st CenturyClinical88Dose fit68Popularity99$0.07/ serving

Nature's Way, Niacin, Vitamin B3, 100 mg, 100 Capsules

Nature's WayClinical88Dose fit71Popularity89$0.03/ serving

Nature's Way, Niacinamide, Non-Flushing, 500 mg, 100 Capsules

Nature's WayClinical89Dose fit90Popularity91$0.09/ serving

21st Century, Sentry, Adults Multivitamin & Multimineral Supplement, 300 Tablets

21st CenturyClinical88Dose fit67Popularity96$0.05/ serving

21st Century, One Daily, Women's, 100 Tablets

21st CenturyClinical88Dose fit67Popularity99$0.07/ serving

Top decision cards

Best products for niacin status

Ranking by · Composite outcome score

Best overall — the composite outcome score.

Top pick · DoseRank

Why this ranks #1 for niacin status

21st Century, Niacinamide, Prolonged Release , 110 Tablets

21st Century$0.05 / serving4.6 · 4,534Available now

Also helps with

Precancerous lesion progression

Skin barrier function

Why this ranks here

Evidence fitNiacinamide is the strongest evidence signal for this outcome.
Dose fitNiacinamide at 500 mg lands inside the studied 15-500 mg window.
Price / serving$0.05 per serving — low price tier for this outcome.
AvailabilityIn stock across major retailers; 99% availability confidence.
TrustStrong trust signals — consistently high marks from verified buyer ratings.

The numbers

500 mgIn rangeinside the studied 15-500 mg window

160 mg

Compare top 3 Product data Open at retailer

The rest of the ranking · DoseRank

Top 10 ranked products

NOW Foods, Niacinamide, 500 mg, 100 Veg Capsules

NOW FoodsClinical89Dose fit90Popularity99$0.08/ serving

Life Extension, Vitamin B3 Niacin, 500 mg, 100 Capsules

Life ExtensionClinical89Dose fit90Popularity96$0.05/ serving

NOW Foods, Niacin, 500 mg, 100 Veg Capsules

NOW FoodsClinical89Dose fit90Popularity96$0.07/ serving

Solaray, Niacinamide, 500 mg, 100 VegCaps

SolarayClinical89Dose fit90Popularity91$0.10/ serving

21st Century, B-Complex plus Vitamin C, 100 Tablets

21st CenturyClinical88Dose fit68Popularity99$0.07/ serving

Nature's Way, Niacin, Vitamin B3, 100 mg, 100 Capsules

Nature's WayClinical88Dose fit71Popularity89$0.03/ serving

Nature's Way, Niacinamide, Non-Flushing, 500 mg, 100 Capsules

Nature's WayClinical89Dose fit90Popularity91$0.09/ serving

21st Century, Sentry, Adults Multivitamin & Multimineral Supplement, 300 Tablets

21st CenturyClinical88Dose fit67Popularity96$0.05/ serving

21st Century, One Daily, Women's, 100 Tablets

21st CenturyClinical88Dose fit67Popularity99$0.07/ serving

Improve niacin status

Improve niacin status

Which ingredient types matter for niacin statusOpen to see which ingredient types matter for niacin status

Vitamins

Best products for niacin status

21st Century, Niacinamide, Prolonged Release , 110 Tablets

NOW Foods, Niacinamide, 500 mg, 100 Veg Capsules

Life Extension, Vitamin B3 Niacin, 500 mg, 100 Capsules

NOW Foods, Niacin, 500 mg, 100 Veg Capsules

Solaray, Niacinamide, 500 mg, 100 VegCaps

21st Century, B-Complex plus Vitamin C, 100 Tablets

Nature's Way, Niacin, Vitamin B3, 100 mg, 100 Capsules

Nature's Way, Niacinamide, Non-Flushing, 500 mg, 100 Capsules

21st Century, Sentry, Adults Multivitamin & Multimineral Supplement, 300 Tablets

21st Century, One Daily, Women's, 100 Tablets

What every metric means

Compare the top 3, side by side

Not sure which is right for you?

Get a personal report

Frequently asked

Which ingredient types matter for niacin statusOpen to see which ingredient types matter for niacin status

Vitamins

Best products for niacin status

21st Century, Niacinamide, Prolonged Release , 110 Tablets

NOW Foods, Niacinamide, 500 mg, 100 Veg Capsules

Life Extension, Vitamin B3 Niacin, 500 mg, 100 Capsules

NOW Foods, Niacin, 500 mg, 100 Veg Capsules

Solaray, Niacinamide, 500 mg, 100 VegCaps

21st Century, B-Complex plus Vitamin C, 100 Tablets

Nature's Way, Niacin, Vitamin B3, 100 mg, 100 Capsules

Nature's Way, Niacinamide, Non-Flushing, 500 mg, 100 Capsules

21st Century, Sentry, Adults Multivitamin & Multimineral Supplement, 300 Tablets

21st Century, One Daily, Women's, 100 Tablets

Compare the top 3, side by side