DOSERANKEVIDENCE-BASED SUPPLEMENTS
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DOSERANKEVIDENCE-BASED SUPPLEMENTS
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  2. ·Outcomes
  3. ·Liver function
  4. ·Gamma-glutamyl transferase (GGT)

Lower GGT

View top productsTake the 60-sec quizGet the reportSee methodology

What this outcome means

Gamma-glutamyl transferase is a liver enzyme whose level in your blood reflects bile-duct health and stress on the liver, including from alcohol. On DoseRank it maps to a defined health outcome built from human studies on serum GGT levels, liver enzyme panels, and cholestasis markers – data sourced from open sources and specialized resources. DoseRank is not medical advice.

Who it's for

Elevated liver enzymesA blood test flagging raised GGT for follow-up.
Alcohol-aware trackingPeople watching how drinking habits register in liver markers.
Bile-flow concernsSigns of cholestasis or blocked bile prompting closer checks.
Stack buildersAlready taking supplements such as Silybin Phytosome and want the dose right.

Evidence level

77Moderate-strong

Silybin Phytosome – has moderate public evidence for this outcome. This usually means there are smaller or mechanistic studies, but not randomized human trials. A DoseFit Score of 67 means this product's ingredient forms and doses are close to what was used in the studies behind this ranking - DoseRank weights each product ingredient.

Best available ingredients

Silybin Phytosome is the best supported ingredient signal for this outcome.

Dose partly matchedDoseFit 67

Scores reward products dosed inside or above the studied range, not just the right ingredient. Examples: In range: Silybin Phytosome 160 mg vs 160-480 mg.

ProcessedProcessedEvery product DoseRank ingested and scored for this outcome, before any availability or relevance filtering.
25
AvailableAvailableOf the products processed, how many are currently in stock and purchasable from a tracked retailer.
25
IngredientsIngredientsNumber of relevant ingredients for this outcome. Each is judged on its own evidence and dose fit score.
1
BrandsBrandsNumber of unique brands represented across the ranked products for this outcome.
15
CoverageCoverageHigher is betterShare of the relevant, in-stock market DoseRank has structured data for. Higher coverage means fewer blind spots in the ranking.
100%

How to read the scores

What every metric means

Each score is 0–100. Higher is better for every metric below.
CompositeThe overall DoseRank score — a weighted blend of clinical strength, evidence, dose fit, trust and value.Higher is better
ClinicalHow strongly the formula's ingredients and doses match what clinical studies used for this outcome.Higher is better
EvidenceHow much published human research backs the formula's key ingredients for this outcome — both how many studies exist and how strong they are.Higher is better
ValueHow the price per serving compares with similar products for this outcome — 50 is the typical price, higher means better value for your money.Higher is better
TrustHow well customers rate this product, with extra weight given to ratings backed by a large number of reviews.Higher is better
PopularityHow strongly this product sells compared with the other ranked products for this outcome.Higher is better

This legend covers the scores on this page — for data sources, scoring weights, and limits, read the full methodology →

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A saved, shareable breakdown: your matched products, dose math, interaction flags to discuss with a clinician, and a price-tracked stack you can revisit.

Questions

Frequently asked

Each product gets a composite score blending clinical strength, evidence, dose fit, trust and value. The #1 on the DoseRank tab has the highest composite; the other tabs re-rank the same products by Value, Trust, or Popularity. Placement is never paid.

No. Dose-fit rewards landing inside the range studied for the outcome — over-dosing (common with melatonin) or under-dosing both lower the score. The goal is the effective dose, not the biggest number.

The Value score compares a product's price per serving with clinically relevant products ranked for the same outcome. A score of 50 is the typical price; above 50 means better value than typical, while below 50 means the product costs more than typical. It is a 0–100 value signal, not a percentile.

Cost is only one input. The cheapest pick here is a citrate form with weaker absorption and a stock-risk flag, so it leads on Value-for-cost but trails on the composite that also weighs evidence, dose fit and availability.

Retailer links may be affiliate links and DoseRank may earn a commission. Rankings and placement are determined by the scoring model only — never by payment from a brand.

No. DoseRank summarizes evidence to help you choose; it is not a substitute for a clinician, especially if you are pregnant, breastfeeding, on medication, or managing a health condition.

DoseRank is not medical advice. Scores summarize publicly available product and study data to help you compare options; they are not a diagnosis or a treatment recommendation. If you are pregnant, breastfeeding, taking medication, or managing a health condition, consult a qualified clinician before starting any supplement. Retailer links may be affiliate links and DoseRank may earn a commission — rankings and placement are determined by the scoring model only, never by payment from a brand. Statements about supplements have not been evaluated by the FDA. Products are not intended to diagnose, treat, cure, or prevent any disease.

Relevant ingredients

Which ingredient types matter for gamma-glutamyl transferase (ggt)Open to see which ingredient types matter for gamma-glutamyl transferase (ggt)

7 products across 1 ingredient types — open to filter the ranking.
Use types to filter ranked products

Botanicals/Herbal Extracts

7 products

Concentrated plant and herbal extracts standardized to actives. Potency depends on the extract ratio and marker content, not raw weight.

Typical:

Top decision cards

Best products for gamma-glutamyl transferase (ggt)

Ranking by · Composite outcome score

Best overall — the composite outcome score.

Top pick · DoseRank

Why this ranks #1 for gamma-glutamyl transferase (ggt)

#1

ProHealth Longevity, Glutathione Triple Boost, 90 Capsules

ProHealth Longevity$1.65 / serving5.0 · 7Available now
Also helps withAntioxidant capacityLiver functionAlanine aminotransferase (ALT)

Why this ranks here

  • Evidence fitSilybin Phytosome has moderate human evidence for this outcome.
  • Dose fitSilybin Phytosome at 160 mg lands inside the studied 160-480 mg window.
  • Price / serving$1.65 per serving — high price tier for this outcome.
  • AvailabilityIn stock across major retailers; 99% availability confidence.
  • TrustLimited trust signals so far for this listing.

The numbers

75
87
67
31

160 mgIn rangeinside the studied 160-480 mg window

40 mg
600 mg
300 mg
Compare top 3Product dataOpen at retailer

The rest of the ranking · DoseRank

Top 10 ranked products
#ProductPrice
2

Nature's Way, Super Milk Thistle®, 120 Vegan Capsules

Nature's Way
Clinical74Dose fit39Popularity30$0.31/ serving
3

Irwin Naturals, MilkThistleTriple-Detox™, 60 Liquid Soft-Gels

Irwin Naturals
Clinical56Dose fit21Popularity30$0.75/ serving
4

Natural Factors, Liver Health Formula, 60 Vegetarian Capsules

Natural Factors
Clinical37Dose fit10Popularity50$0.63/ serving
5

DaVinci Laboratories, Multiphase Detox™, 90 Capsules

DaVinci Laboratories
Clinical37Dose fit10Popularity30$1.91/ serving
6

Live Conscious, Liver Well With NAC & ALA & Siliphos® Milk Thistle, 60 Capsules

Live Conscious
Clinical20Dose fit4Popularity50$1.01/ serving
7

Life Extension, Advanced Milk Thistle, 120 Softgels

Life Extension
Clinical0Dose fit—Popularity96$0.52/ serving
8

Thorne, S.A.T.®, 60 Capsules

Thorne
Clinical0Dose fit—Popularity99$0.70/ serving
9

Thorne, Milk Thistle Phytosome, 90 Capsules (180 mg per Capsule)

Thorne
Clinical0Dose fit—Popularity91$0.48/ serving
10

Life Extension, Milk Thistle, 60 Vegetarian Capsules (750 mg per Capsule)

Life Extension
Clinical0Dose fit—Popularity50$0.39/ serving

Keep exploring

Related outcomes

Alanine aminotransferase (ALT)Liver enzyme used to assess hepatocellular injury.Alkaline phosphataseEnzyme related to bile ducts, bone, and liver.Aspartate aminotransferase (AST)Enzyme used to assess liver and muscle injury.Liver functionOverall biochemical or clinical hepatic performance.
Last updated Aug 20, 2026

DoseRank is not medical advice. Scores summarize publicly available product and study data to help you compare options; they are not a diagnosis or a treatment recommendation. If you are pregnant, breastfeeding, taking medication, or managing a health condition, consult a qualified clinician before starting any supplement. Retailer links may be affiliate links and DoseRank may earn a commission — rankings and placement are determined by the scoring model only, never by payment from a brand. Statements about supplements have not been evaluated by the FDA. Products are not intended to diagnose, treat, cure, or prevent any disease.

Comparison preview

Compare the top 3, side by side

Sign-in to see all metrics

The top three for the current view — free to read, no account. Saving, exporting, alerts and the full filter set unlock once you sign in or build a personal report.

Metric
#1ProHealth Longevity, Glutathione Triple Boost, 90 CapsulesProHealth Longevity · $1.65/serving
#2Nature's Way, Super Milk Thistle®, 120 Vegan CapsulesNature's Way · $0.31/serving
#3Irwin Naturals, MilkThistleTriple-Detox™, 60 Liquid Soft-GelsIrwin Naturals · $0.75/serving
Composite756749
Clinical877456
Dose fit673921
Value317150
Popularity303030
Key dosages & price · raw values
160 mgHighest140 mg120 mg
Rating
Number of ratings
Price
Price per serving
Serving size
Trust

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Unlocks with accountFull list of ingredients and dosagesFull list of metricsPrice-drop alertsRanking-changes alertsPersistent stack