DOSERANKEVIDENCE-BASED SUPPLEMENTS
DOSERANKEVIDENCE-BASED SUPPLEMENTS© 2026 DoseRank · Evidence-based supplements
Methodology·Outcomes·Categories
DOSERANKEVIDENCE-BASED SUPPLEMENTS
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  2. ·Outcomes
  3. ·Kidney function
  4. ·Kidney function

Improve kidney function

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What this outcome means

Kidney function is how well your kidneys filter waste, balance fluids, and clear toxins from your blood. On DoseRank it maps to a defined health outcome built from human studies on eGFR, serum creatinine, and urinary albumin – data sourced from open sources and specialized resources. DoseRank is not medical advice.

Who it's for

Early declineAdults whose lab numbers show filtration slipping over time.
Diabetes or hypertensionPeople whose conditions put steady strain on the kidneys.
Aging kidneysOlder adults wanting to protect filtration as they age.
Stack buildersAlready taking supplements such as Astragalus and want the dose right.

Evidence level

78Moderate-strong

Astragalus – has moderate public evidence for this outcome. This usually means there are smaller or mechanistic studies, but not randomized human trials. A DoseFit Score of 67 means this product's ingredient forms and doses are close to what was used in the studies behind this ranking - DoseRank weights each product ingredient.

Best available ingredients

Astragalus is the best supported ingredient signal for this outcome.

Dose partly matchedDoseFit 67

Scores reward products dosed inside or above the studied range, not just the right ingredient. Examples: In range: Astragalus 1000 mg vs 1000-3000 mg.

ProcessedProcessedEvery product DoseRank ingested and scored for this outcome, before any availability or relevance filtering.
602
AvailableAvailableOf the products processed, how many are currently in stock and purchasable from a tracked retailer.
602
IngredientsIngredientsNumber of relevant ingredients for this outcome. Each is judged on its own evidence and dose fit score.
5
BrandsBrandsNumber of unique brands represented across the ranked products for this outcome.
165
CoverageCoverageHigher is betterShare of the relevant, in-stock market DoseRank has structured data for. Higher coverage means fewer blind spots in the ranking.
100%

How to read the scores

What every metric means

Each score is 0–100. Higher is better for every metric below.
CompositeThe overall DoseRank score — a weighted blend of clinical strength, evidence, dose fit, trust and value.Higher is better
ClinicalHow strongly the formula's ingredients and doses match what clinical studies used for this outcome.Higher is better
EvidenceHow much published human research backs the formula's key ingredients for this outcome — both how many studies exist and how strong they are.Higher is better
ValueHow the price per serving compares with similar products for this outcome — 50 is the typical price, higher means better value for your money.Higher is better
TrustHow well customers rate this product, with extra weight given to ratings backed by a large number of reviews.Higher is better
PopularityHow strongly this product sells compared with the other ranked products for this outcome.Higher is better

This legend covers the scores on this page — for data sources, scoring weights, and limits, read the full methodology →

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A saved, shareable breakdown: your matched products, dose math, interaction flags to discuss with a clinician, and a price-tracked stack you can revisit.

Questions

Frequently asked

Each product gets a composite score blending clinical strength, evidence, dose fit, trust and value. The #1 on the DoseRank tab has the highest composite; the other tabs re-rank the same products by Value, Trust, or Popularity. Placement is never paid.

DoseRank is not medical advice. Scores summarize publicly available product and study data to help you compare options; they are not a diagnosis or a treatment recommendation. If you are pregnant, breastfeeding, taking medication, or managing a health condition, consult a qualified clinician before starting any supplement. Retailer links may be affiliate links and DoseRank may earn a commission — rankings and placement are determined by the scoring model only, never by payment from a brand. Statements about supplements have not been evaluated by the FDA. Products are not intended to diagnose, treat, cure, or prevent any disease.

Relevant ingredients

Which ingredient types matter for kidney functionOpen to see which ingredient types matter for kidney function

593 products across 2 ingredient types — open to filter the ranking.
Use types to filter ranked products

Botanicals/Herbal Extracts

541 products

Concentrated plant and herbal extracts standardized to actives. Potency depends on the extract ratio and marker content, not raw weight.

Typical: , , , ...

Adsorbents & Inert Functional Materials

52 products

Binding agents like charcoal and silica that adsorb or stabilize. Functional and non-nutritive – they can bind nutrients, so time them apart.

Typical:

Top decision cards

Best products for kidney function

Ranking by · Composite outcome score

Best overall — the composite outcome score.

Top pick · DoseRank

Why this ranks #1 for kidney function

#1

NOW Foods, Astragalus, 500 mg, 100 Veg Capsules

NOW Foods$0.14 / serving4.7 · 3,509Available now

Why this ranks here

  • Evidence fitAstragalus has moderate human evidence for this outcome.
  • Dose fitAstragalus at 1000 mg lands inside the studied 1000-3000 mg window.
  • Price / serving$0.14 per serving — low price tier for this outcome.
  • AvailabilityIn stock across major retailers; 99% availability confidence.
  • TrustStrong trust signals — consistently high marks from verified buyer ratings.

Trade-offs

Dose fit is the weak spot on this listEvidence depth trails the rest of this list

The numbers

83
86
67
81

1000 mgIn rangeinside the studied 1000-3000 mg window
Compare top 3Product dataOpen at retailer

The rest of the ranking · DoseRank

Top 10 ranked products
#ProductPrice

Keep exploring

Related outcomes

Albuminuria or proteinuriaProtein leakage into urine indicating kidney damage risk.Serum creatinineBlood marker commonly used to estimate kidney function.
Last updated Jun 12, 2026

DoseRank is not medical advice. Scores summarize publicly available product and study data to help you compare options; they are not a diagnosis or a treatment recommendation. If you are pregnant, breastfeeding, taking medication, or managing a health condition, consult a qualified clinician before starting any supplement. Retailer links may be affiliate links and DoseRank may earn a commission — rankings and placement are determined by the scoring model only, never by payment from a brand. Statements about supplements have not been evaluated by the FDA. Products are not intended to diagnose, treat, cure, or prevent any disease.

Comparison preview

Compare the top 3, side by side

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The top three for the current view — free to read, no account. Saving, exporting, alerts and the full filter set unlock once you sign in or build a personal report.

Metric
#1NOW Foods, Astragalus, 500 mg, 100 Veg CapsulesNOW Foods · $0.14/serving
#2NOW Foods, Cordyceps, 90 Veg Capsules (750 mg per Capsule)NOW Foods · $0.36/serving
#3Nature's Way, Astragalus Root, 180 Vegan Capsules (470 mg per Capsule)Nature's Way · $0.25/serving
Composite838382
Clinical868787
Dose fit677071
Value816270
Popularity839180
Key dosages & price · raw values
1000 mgHighest——
Rating
Number of ratings
Price
Price per serving
Serving size
Trust

See more metrics for every product.

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Unlocks with accountFull list of ingredients and dosagesFull list of metricsPrice-drop alertsRanking-changes alertsPersistent stack