DOSERANKEVIDENCE-BASED SUPPLEMENTS
DOSERANKEVIDENCE-BASED SUPPLEMENTS© 2026 DoseRank · Evidence-based supplements
Methodology·Outcomes·Categories
DOSERANKEVIDENCE-BASED SUPPLEMENTS
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  2. ·Outcomes
  3. ·Metabolism
  4. ·Resting energy expenditure

Increase resting metabolism

View top productsTake the 60-sec quizGet the reportSee methodology

What this outcome means

Resting energy expenditure is the number of calories your body burns just to keep itself running at rest. On DoseRank it maps to a defined health outcome built from human studies on basal metabolic rate, resting calorie burn measured by indirect calorimetry, and metabolic rate per unit of lean mass – data sourced from open sources and specialized resources. DoseRank is not medical advice.

Who it's for

Slow metabolismFeeling like calories burn off more sluggishly than they used to.
Dieting plateauProgress stalling as resting burn drops during a prolonged cut.
Body-composition trackersPeople mapping metabolic rate against changes in muscle and weight.
Stack buildersAlready taking supplements such as Synephrine and want the dose right.

Evidence level

92Strong

Synephrine – has strong public evidence. DoseRank looks at both evidence quality and formula fit. A DoseFit Score of 92 means this product's ingredient forms and doses are close to what was used in the studies behind this ranking - DoseRank weights each product ingredient.

Best ingredients

Synephrine is the best supported ingredient signal for this outcome.

Dose matchedDoseFit 92

Scores reward products dosed inside or above the studied range, not just the right ingredient. Examples: Above range: Synephrine 157.6 mg vs 25-100 mg.

ProcessedProcessedEvery product DoseRank ingested and scored for this outcome, before any availability or relevance filtering.
9.2k
AvailableAvailableOf the products processed, how many are currently in stock and purchasable from a tracked retailer.
9.2k
IngredientsIngredientsNumber of relevant ingredients for this outcome. Each is judged on its own evidence and dose fit score.
7
BrandsBrandsNumber of unique brands represented across the ranked products for this outcome.
634
CoverageCoverageHigher is betterShare of the relevant, in-stock market DoseRank has structured data for. Higher coverage means fewer blind spots in the ranking.
100%

How to read the scores

What every metric means

Each score is 0–100. Higher is better for every metric below.
CompositeThe overall DoseRank score — a weighted blend of clinical strength, evidence, dose fit, trust and value.Higher is better
ClinicalHow strongly the formula's ingredients and doses match what clinical studies used for this outcome.Higher is better
EvidenceHow much published human research backs the formula's key ingredients for this outcome — both how many studies exist and how strong they are.Higher is better
ValueHow the price per serving compares with similar products for this outcome — 50 is the typical price, higher means better value for your money.Higher is better
TrustHow well customers rate this product, with extra weight given to ratings backed by a large number of reviews.Higher is better
PopularityHow strongly this product sells compared with the other ranked products for this outcome.Higher is better

This legend covers the scores on this page — for data sources, scoring weights, and limits, read the full methodology →

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A saved, shareable breakdown: your matched products, dose math, interaction flags to discuss with a clinician, and a price-tracked stack you can revisit.

Questions

Frequently asked

Each product gets a composite score blending clinical strength, evidence, dose fit, trust and value. The #1 on the DoseRank tab has the highest composite; the other tabs re-rank the same products by Value, Trust, or Popularity. Placement is never paid.

DoseRank is not medical advice. Scores summarize publicly available product and study data to help you compare options; they are not a diagnosis or a treatment recommendation. If you are pregnant, breastfeeding, taking medication, or managing a health condition, consult a qualified clinician before starting any supplement. Retailer links may be affiliate links and DoseRank may earn a commission — rankings and placement are determined by the scoring model only, never by payment from a brand. Statements about supplements have not been evaluated by the FDA. Products are not intended to diagnose, treat, cure, or prevent any disease.

Relevant ingredients

Which ingredient types matter for resting energy expenditureOpen to see which ingredient types matter for resting energy expenditure

895 products across 3 ingredient types — open to filter the ranking.
Use types to filter ranked products

Alkaloids & Stimulants

857 products

Plant-derived nitrogen compounds like caffeine that stimulate the nervous system. Effective but dose-sensitive, with real tolerance and dependence risk.

Typical: ,

Botanicals/Herbal Extracts

23 products

Concentrated plant and herbal extracts standardized to actives. Potency depends on the extract ratio and marker content, not raw weight.

Typical:

Glandulars & Animal-Derived Extracts

15 products

Animal gland and organ-tissue extracts used traditionally for targeted organ support. Purity and grass-fed sourcing are the key quality markers.

Typical:

Top decision cards

Best products for resting energy expenditure

Ranking by · Composite outcome score

Best overall — the composite outcome score.

Top pick · DoseRank

Why this ranks #1 for resting energy expenditure

#1

Nutrex Research, LIPO-6 Black, Ultra Concentrate, 60 Liqui-Caps

Nutrex Research$0.37 / serving4.4 · 8,412Available now

Why this ranks here

  • Evidence fitSynephrine is the strongest evidence signal for this outcome.
  • Dose fitSynephrine at 157.6 mg is higher than the studied 25-100 mg window.
  • Price / serving$0.37 per serving — mid price tier for this outcome.
  • AvailabilityIn stock across major retailers; 99% availability confidence.
  • TrustStrong trust signals — consistently high marks from verified buyer ratings.

Trade-offs

Value for money trails the rest of this listPopularity trails the other picks here

The numbers

84
89
92
62

157.6 mgAbove rangehigher than the studied 25-100 mg window
Compare top 3Product dataOpen at retailer

The rest of the ranking · DoseRank

Top 10 ranked products
#ProductPrice

Keep exploring

Related outcomes

Fat oxidationUse of fat as an energy source.Ketone levelsCirculating ketone concentrations, relevant in fasting or ketogenic states.ThermogenesisHeat production and metabolic energy expenditure.
Last updated Jun 16, 2026

DoseRank is not medical advice. Scores summarize publicly available product and study data to help you compare options; they are not a diagnosis or a treatment recommendation. If you are pregnant, breastfeeding, taking medication, or managing a health condition, consult a qualified clinician before starting any supplement. Retailer links may be affiliate links and DoseRank may earn a commission — rankings and placement are determined by the scoring model only, never by payment from a brand. Statements about supplements have not been evaluated by the FDA. Products are not intended to diagnose, treat, cure, or prevent any disease.

Comparison preview

Compare the top 3, side by side

Sign-in to see all metrics

The top three for the current view — free to read, no account. Saving, exporting, alerts and the full filter set unlock once you sign in or build a personal report.

Metric
#1Nutrex Research, LIPO-6 Black, Ultra Concentrate, 60 Liqui-CapsNutrex Research · $0.37/serving
#2Source Naturals, BioPerine®, 10 mg, 120 TabletsSource Naturals · $0.08/serving
#3California Gold Nutrition, Silymarin Complex with Milk Thistle Extract Plus Dandelion, Artichoke, Ginger, and BioPerine®, 360 Veggie CapsulesCalifornia Gold Nutrition · $0.08/serving
Composite848282
Clinical898583
Dose fit929075
Value628888
Popularity838399
Key dosages & price · raw values
157.55 mgHighest——
Rating
Number of ratings
Price
Price per serving
Serving size
Trust

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Unlocks with accountFull list of ingredients and dosagesFull list of metricsPrice-drop alertsRanking-changes alertsPersistent stack