DOSERANKEVIDENCE-BASED SUPPLEMENTS
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DOSERANKEVIDENCE-BASED SUPPLEMENTS
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  2. ·Outcomes
  3. ·Pain
  4. ·Pain intensity

Reduce pain

View top productsTake the 60-sec quizGet the reportSee methodology

What this outcome means

Pain intensity is how strong your pain feels at a given moment, whatever its source or location in the body. On DoseRank it maps to a defined health outcome built from human studies on validated pain scales, numeric rating scores, and visual analog measures – data sourced from open sources and specialized resources. DoseRank is not medical advice.

Who it's for

Persistent daily painPeople living with ongoing discomfort that shapes their routine.
Flare-up sufferersThose whose pain comes in sharp, unpredictable episodes.
Post-exertion sorenessPeople sore after activity, injury, or physical strain.
Stack buildersAlready taking supplements such as DL-Phenylalanine and want the dose right.

Evidence level

60Limited

Evidence score is low, which means that there is not enough data to support the effectiveness of this outcome. However, we will continue to monitor the research and update our recommendations as new information becomes available.

Thin ingredient signal

DL-Phenylalanine is the best available ingredient signal for this outcome, but the evidence is still thin.

Dose partly matchedDoseFit 67

Scores reward products dosed inside or above the studied range, not just the right ingredient. Examples: In range: DL-Phenylalanine 1000 mg vs 1000-2500 mg.

ProcessedProcessedEvery product DoseRank ingested and scored for this outcome, before any availability or relevance filtering.
927
AvailableAvailableOf the products processed, how many are currently in stock and purchasable from a tracked retailer.
927
IngredientsIngredientsNumber of relevant ingredients for this outcome. Each is judged on its own evidence and dose fit score.
5
BrandsBrandsNumber of unique brands represented across the ranked products for this outcome.
170
CoverageCoverageHigher is betterShare of the relevant, in-stock market DoseRank has structured data for. Higher coverage means fewer blind spots in the ranking.
100%

How to read the scores

What every metric means

Each score is 0–100. Higher is better for every metric below.
CompositeThe overall DoseRank score — a weighted blend of clinical strength, evidence, dose fit, trust and value.Higher is better
ClinicalHow strongly the formula's ingredients and doses match what clinical studies used for this outcome.Higher is better
EvidenceHow much published human research backs the formula's key ingredients for this outcome — both how many studies exist and how strong they are.Higher is better
ValueHow the price per serving compares with similar products for this outcome — 50 is the typical price, higher means better value for your money.Higher is better
TrustHow well customers rate this product, with extra weight given to ratings backed by a large number of reviews.Higher is better
PopularityHow strongly this product sells compared with the other ranked products for this outcome.Higher is better

This legend covers the scores on this page — for data sources, scoring weights, and limits, read the full methodology →

Not sure which is right for you?

Answer a few questions about your goals, habits, stack, and budget. Then, DoseRank will find the products that best match your needs based on your answers. It's free and only takes 60 seconds! No account is required.

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Get a personal report

A saved, shareable breakdown: your matched products, dose math, interaction flags to discuss with a clinician, and a price-tracked stack you can revisit.

Questions

Frequently asked

Each product gets a composite score blending clinical strength, evidence, dose fit, trust and value. The #1 on the DoseRank tab has the highest composite; the other tabs re-rank the same products by Value, Trust, or Popularity. Placement is never paid.

No. Dose-fit rewards landing inside the range studied for the outcome — over-dosing (common with melatonin) or under-dosing both lower the score. The goal is the effective dose, not the biggest number.

The Value score compares a product's price per serving with clinically relevant products ranked for the same outcome. A score of 50 is the typical price; above 50 means better value than typical, while below 50 means the product costs more than typical. It is a 0–100 value signal, not a percentile.

Cost is only one input. The cheapest pick here is a citrate form with weaker absorption and a stock-risk flag, so it leads on Value-for-cost but trails on the composite that also weighs evidence, dose fit and availability.

Retailer links may be affiliate links and DoseRank may earn a commission. Rankings and placement are determined by the scoring model only — never by payment from a brand.

No. DoseRank summarizes evidence to help you choose; it is not a substitute for a clinician, especially if you are pregnant, breastfeeding, on medication, or managing a health condition.

DoseRank is not medical advice. Scores summarize publicly available product and study data to help you compare options; they are not a diagnosis or a treatment recommendation. If you are pregnant, breastfeeding, taking medication, or managing a health condition, consult a qualified clinician before starting any supplement. Retailer links may be affiliate links and DoseRank may earn a commission — rankings and placement are determined by the scoring model only, never by payment from a brand. Statements about supplements have not been evaluated by the FDA. Products are not intended to diagnose, treat, cure, or prevent any disease.

Relevant ingredients

Which ingredient types matter for pain intensityOpen to see which ingredient types matter for pain intensity

323 products across 2 ingredient types — open to filter the ranking.
Use types to filter ranked products

Amino Acids & Derivatives

29 products

The building blocks of protein, taken singly for targeted effects – leucine for muscle, theanine for calm. Free-form versions absorb fast on an empty stomach.

Typical:

Minerals & Trace Elements

294 products

Inorganic nutrients from calcium to zinc. The chemical form drives absorption – chelates and citrates usually beat cheap oxides.

Typical:

Top decision cards

Best products for pain intensity

Ranking by · Composite outcome score

Best overall — the composite outcome score.

Top pick · DoseRank

Why this ranks #1 for pain intensity

#1

Nutra BioGenesis, Ultra Lean™ Appetite Control, 120 Capsules

Nutra BioGenesis$1.47 / serving4.2 · 33Available now
Also helps withVitamin B6 statusVitamin C statusNausea

Why this ranks here

  • Evidence fitEvidence is still thin for DL-Phenylalanine.
  • Dose fitDL-Phenylalanine at 1000 mg lands inside the studied 1000-2500 mg window.
  • Price / serving$1.47 per serving — high price tier for this outcome.
  • AvailabilityIn stock across major retailers; 99% availability confidence.
  • TrustLimited trust signals so far for this listing.

The numbers

36
43
67
20

1000 mgIn rangeinside the studied 1000-2500 mg window

50 mg
500 mcg
100 mg
375 mg
75 mg
600 mg
25 mg
Compare top 3Product dataOpen at retailer

The rest of the ranking · DoseRank

Top 10 ranked products
#ProductPrice
2

Seeking Health, Magnesium Malate Powder, 8.82 oz (250 g)

Seeking Health
Clinical26Dose fit82Popularity89$0.22/ serving
3

Source Naturals, Magnesium Malate, 360 Tablets (1,250 mg per Tablet)

Source Naturals
Clinical26Dose fit76Popularity89$0.27/ serving
4

Jigsaw Health, MagSRT® B-Free, 240 Tablets

Jigsaw Health
Clinical27Dose fit95Popularity76$0.79/ serving
5

Source Naturals, Magnesium Malate, 180 Tablets

Source Naturals
Clinical26Dose fit76Popularity84$0.28/ serving
6

Nature's Life, Renewing Magnesium Malate, 250 Tablets (200 mg per Tablet)

Nature's Life
Clinical26Dose fit74Popularity76$0.20/ serving
7

Nutricost, Magnesium Malate, Unflavored, 10.7 oz (300 g)

Nutricost
Clinical26Dose fit76Popularity76$0.15/ serving
8

Nutricost, Magnesium Malate, 180 Capsules (700 mg per Capsule)

Nutricost
Clinical26Dose fit76Popularity84$0.24/ serving
9

KAL, Magnesium Malate 400, 90 Tablets (200 mg per Tablet)

KAL
Clinical26Dose fit74Popularity98$0.35/ serving
10

Jigsaw Health, MagSRT®, 240 Tablets

Jigsaw Health
Clinical26Dose fit82Popularity76$0.79/ serving

Keep exploring

Related outcomes

Back painPain localized to the back.
Last updated Aug 20, 2026

DoseRank is not medical advice. Scores summarize publicly available product and study data to help you compare options; they are not a diagnosis or a treatment recommendation. If you are pregnant, breastfeeding, taking medication, or managing a health condition, consult a qualified clinician before starting any supplement. Retailer links may be affiliate links and DoseRank may earn a commission — rankings and placement are determined by the scoring model only, never by payment from a brand. Statements about supplements have not been evaluated by the FDA. Products are not intended to diagnose, treat, cure, or prevent any disease.

Comparison preview

Compare the top 3, side by side

Sign-in to see all metrics

The top three for the current view — free to read, no account. Saving, exporting, alerts and the full filter set unlock once you sign in or build a personal report.

Metric
#1Nutra BioGenesis, Ultra Lean™ Appetite Control, 120 CapsulesNutra BioGenesis · $1.47/serving
#2Seeking Health, Magnesium Malate Powder, 8.82 oz (250 g)Seeking Health · $0.22/serving
#3Source Naturals, Magnesium Malate, 360 Tablets (1,250 mg per Tablet)Source Naturals · $0.27/serving
Composite362525
Clinical432626
Dose fit678276
Value206358
Popularity308989
Key dosages & price · raw values
1000 mgHighest——
Rating
Number of ratings
Price
Price per serving
Serving size
Trust

See more metrics for every product.

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Unlocks with accountFull list of ingredients and dosagesFull list of metricsPrice-drop alertsRanking-changes alertsPersistent stack