The short answer · Aspartate aminotransferase (AST)
Take silymarin for aspartate aminotransferase (ast). This is the one to buy.

NOW Foods, Milk Thistle Extract, 750 mg, 90 Veg Capsules
4.8· 4,117 ratings· $0.23/serving
Silymarin 600 mg — inside the studied 140-700 mg window
Of 494 products scored for Aspartate aminotransferase (AST), NOW Foods, Milk Thistle Extract, 750 mg, 90 Veg Capsules ranks #1 with a DoseRank score of 85. Silymarin is the strongest evidence signal for this outcome.
Retailer links may be affiliate links. Rankings and placement are never paid.
The form“Why Silymarin — not Milk Thistle or Artichoke Extract?”Evidence Strong evidence
Silymarin is the strongest evidence signal for this outcome.
- SilymarinThe pick
Strong evidence · 600 mg
The active flavonoid complex from milk thistle (Silybum marianum) and its main bioactive; supports liver cells by stabilizing membranes and acting as an antioxidant.
- Milk Thistle
Strong evidence · 250 mg
Extract of Silybum marianum seeds; its silymarin flavonolignans are antioxidant compounds traditionally used to support liver cells and buffer against hepatotoxins.
- Artichoke Extract
Moderate evidence · 50 mg
Standardized extract from Cynara scolymus leaves rich in cynarin and luteolin; supports bile flow, liver function, and has modest evidence for cholesterol reduction.
The dose“Is the dose actually effective?”Dose fit 86
Silymarin at 600 mg lands inside the studied 140-700 mg window.
Silymarin
Studied window 140-700 mg · this pick 600 mg
The ranking“Why should I trust this pick?”Trust 93
Strong trust signals — consistently high marks from verified buyer ratings. Each product gets a DoseRank score blending clinical strength, evidence, dose fit, trust and value. Retailer links may be affiliate links — the scoring model decides placement, never payment from a brand.
- 494 products scored
- Never paid placement
- Evidence level: Strong · 88
- 125 brands
- 4 ingredients
The price“Can I do better than $0.23 a serving?”Value 69
$0.23 per serving — mid price tier for this outcome. The cheapest ranked pick here is $0.12 per serving.
- 2NOW Foods, Milk Thistle Extract, 300 mg, 200 Veg CapsulesScore 85 · $0.12/servingiHerb
- 6California Gold Nutrition, Milk Thistle Plus with Turmeric Extract and Artichoke Extract, 120 Veggie CapsulesScore 83 · $0.12/servingiHerb
Why not the absolute cheapest? The DoseRank score also weighs clinical strength, evidence, dose fit and trust — the very cheapest listings rarely hold up everywhere else.
Ready?
The #1 pick is $0.23 a serving.NOW Foods, Milk Thistle Extract, 750 mg, 90 Veg Capsules — in stock at a tracked retailer.
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NOW Foods, Milk Thistle Extract, 750 mg, 90 Veg Capsules ranks #1 for Aspartate aminotransferase (AST) with a DoseRank score of 85. The score blends clinical strength, evidence, dose fit, trust signals and value across 494 products scored for this outcome.
Keep exploring
Other outcomes
- Alanine aminotransferase (ALT)Liver enzyme used to assess hepatocellular injury.
- Alkaline phosphataseEnzyme related to bile ducts, bone, and liver.
- Gamma-glutamyl transferase (GGT)Marker of cholestasis, alcohol exposure, or hepatic stress.
- Liver functionOverall biochemical or clinical hepatic performance.