The short answer · Hepatotoxicity or liver injury

Nature's Answer, Milk Thistle Seed, Fluid Extract, 2,000 mg, 2 fl oz (60 ml)
4.8· 6,056 ratings· $0.67/serving
Silymarin 2000 mg — higher than the studied 420-1200 mg window
Of 6,174 products scored for Hepatotoxicity or liver injury, Nature's Answer, Milk Thistle Seed, Fluid Extract, 2,000 mg, 2 fl oz (60 ml) ranks #1 with a DoseRank score of 83. Silymarin has moderate human evidence for this outcome.
Silymarin has moderate human evidence for this outcome.
Moderate evidence · 2000 mg
The active flavonoid complex from milk thistle (Silybum marianum) and its main bioactive; supports liver cells by stabilizing membranes and acting as an antioxidant.
Silymarin at 2000 mg is higher than the studied 420-1200 mg window.
Silymarin
Questions
Nature's Answer, Milk Thistle Seed, Fluid Extract, 2,000 mg, 2 fl oz (60 ml) ranks #1 for Hepatotoxicity or liver injury with a DoseRank score of 83. The score blends clinical strength, evidence, dose fit, trust signals and value across 6,174 products scored for this outcome.
Silymarin has moderate human evidence for this outcome.
Silymarin at 2000 mg is higher than the studied 420-1200 mg window. DoseRank scores this product's dose fit at 92 out of 100.
Nature's Answer, Milk Thistle Seed, Fluid Extract, 2,000 mg, 2 fl oz (60 ml) works out at $0.67 per serving. $0.67 per serving — high price tier for this outcome. The cheapest ranked pick here is $0.17 per serving.
No. Retailer links may be affiliate links, but rankings and placement are never paid. Every product is scored by the same public model, and the ranking is recomputed from the underlying product data rather than edited by hand.
Retailer links may be affiliate links. Rankings and placement are never paid.
Studied window 420-1200 mg · this pick 2000 mg
Strong trust signals — consistently high marks from verified buyer ratings. Each product gets a DoseRank score blending clinical strength, evidence, dose fit, trust and value. Retailer links may be affiliate links — the scoring model decides placement, never payment from a brand.
$0.67 per serving — high price tier for this outcome. The cheapest ranked pick here is $0.17 per serving.
Why not the absolute cheapest? The DoseRank score also weighs clinical strength, evidence, dose fit and trust — the very cheapest listings rarely hold up everywhere else.
Ready?
The #1 pick is $0.67 a serving.Nature's Answer, Milk Thistle Seed, Fluid Extract, 2,000 mg, 2 fl oz (60 ml) — in stock at a tracked retailer.
View on iHerbA saved, shareable breakdown: your matched products, dose math, and interaction flags to discuss with a clinician.
Or take the 60-sec quiz →