The short answer · Hepatotoxicity or liver injury
Take silymarin for hepatotoxicity or liver injury. This is the one to buy.

NOW Foods, Milk Thistle Extract, 750 mg, 90 Veg Capsules
4.8· 4,117 ratings· $0.23/serving
Silymarin 600 mg — inside the studied 420-1200 mg window
Of 4,788 products scored for Hepatotoxicity or liver injury, NOW Foods, Milk Thistle Extract, 750 mg, 90 Veg Capsules ranks #1 with a DoseRank score of 83. Silymarin has moderate human evidence for this outcome.
Retailer links may be affiliate links. Rankings and placement are never paid.
The form“Why Silymarin — not Niacinamide?”Evidence Moderate evidence
Silymarin has moderate human evidence for this outcome.
- SilymarinThe pick
Moderate evidence · 600 mg
The active flavonoid complex from milk thistle (Silybum marianum) and its main bioactive; supports liver cells by stabilizing membranes and acting as an antioxidant.
- Niacinamide
Limited evidence · 50 mg
Non-flushing form of vitamin B3; serves as a NAD+ precursor for energy metabolism and DNA repair, and is preferred over niacin when avoiding flush.
The dose“Is the dose actually effective?”Dose fit 72
Silymarin at 600 mg lands inside the studied 420-1200 mg window.
Silymarin
Studied window 420-1200 mg · this pick 600 mg
The ranking“Why should I trust this pick?”Trust 93
Strong trust signals — consistently high marks from verified buyer ratings. Each product gets a DoseRank score blending clinical strength, evidence, dose fit, trust and value. Retailer links may be affiliate links — the scoring model decides placement, never payment from a brand.
- 4,788 products scored
- Never paid placement
- Evidence level: Moderate · 78
- 436 brands
- 20 ingredients
The price“Can I do better than $0.23 a serving?”Value 63
$0.23 per serving — mid price tier for this outcome. The cheapest ranked pick here is $0.20 per serving.
- 9NOW Foods, Milk Thistle Extract, 450 mg, 120 SoftgelsScore 66 · $0.20/servingiHerb
Why not the absolute cheapest? The DoseRank score also weighs clinical strength, evidence, dose fit and trust — the very cheapest listings rarely hold up everywhere else.
Ready?
The #1 pick is $0.23 a serving.NOW Foods, Milk Thistle Extract, 750 mg, 90 Veg Capsules — in stock at a tracked retailer.
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NOW Foods, Milk Thistle Extract, 750 mg, 90 Veg Capsules ranks #1 for Hepatotoxicity or liver injury with a DoseRank score of 83. The score blends clinical strength, evidence, dose fit, trust signals and value across 4,788 products scored for this outcome.