The short answer · HDL cholesterol

Life Extension, Vitamin B3 Niacin, 500 mg, 100 Capsules
4.6· 8,823 ratings· $0.05/serving
Niacin 500 mg — inside the studied 500-3000 mg window
Of 4,417 products scored for HDL cholesterol, Life Extension, Vitamin B3 Niacin, 500 mg, 100 Capsules ranks #1 with a DoseRank score of 85. Niacin and Vitamin B3 are the strongest evidence signals for this outcome.
Niacin and Vitamin B3 are the strongest evidence signals for this outcome.
Strong evidence · 500 mg
Vitamin B3 as nicotinic acid; a NAD+ precursor that can raise HDL but causes a prostaglandin-mediated skin flush at higher doses.
Strong evidence · 500 mg
Niacin, a B vitamin and NAD+ precursor; used at high doses to lower triglycerides and raise HDL, with skin flushing as the hallmark side effect.
Questions
Life Extension, Vitamin B3 Niacin, 500 mg, 100 Capsules ranks #1 for HDL cholesterol with a DoseRank score of 85. The score blends clinical strength, evidence, dose fit, trust signals and value across 4,417 products scored for this outcome.
Niacin and Vitamin B3 are the strongest evidence signals for this outcome.
1 of 2 dosed ingredients land in the studied range. Niacin at 500 mg lands inside the studied 500-3000 mg window. DoseRank scores this product's dose fit at 67 out of 100.
Life Extension, Vitamin B3 Niacin, 500 mg, 100 Capsules works out at $0.05 per serving. $0.05 per serving — mid price tier for this outcome. The cheapest ranked pick here is $0.05 per serving.
No. Retailer links may be affiliate links, but rankings and placement are never paid. Every product is scored by the same public model, and the ranking is recomputed from the underlying product data rather than edited by hand.
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Retailer links may be affiliate links. Rankings and placement are never paid.
1 of 2 dosed ingredients land in the studied range. Niacin at 500 mg lands inside the studied 500-3000 mg window.
Niacin
Studied window 500-3000 mg · this pick 500 mg
Vitamin B3
Studied window 1000-3000 mg · this pick 500 mg
Strong trust signals — consistently high marks from verified buyer ratings. Each product gets a DoseRank score blending clinical strength, evidence, dose fit, trust and value. Retailer links may be affiliate links — the scoring model decides placement, never payment from a brand.
$0.05 per serving — mid price tier for this outcome. The cheapest ranked pick here is $0.05 per serving.
Why not the absolute cheapest? The DoseRank score also weighs clinical strength, evidence, dose fit and trust — the very cheapest listings rarely hold up everywhere else.
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The #1 pick is $0.05 a serving.Life Extension, Vitamin B3 Niacin, 500 mg, 100 Capsules — in stock at a tracked retailer.
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