What dose of Niacin is effective for HDL cholesterol?

Niacin at 500 mg lands inside the studied 500-3000 mg window. DoseRank scores this product's dose fit at 67 out of 100.

How much does the best HDL cholesterol supplement cost?

Life Extension, Vitamin B3 Niacin, 500 mg, 100 Capsules works out at $0.06 per serving. $0.06 per serving — mid price tier for this outcome. The cheapest ranked pick here is $0.05 per serving.

Does DoseRank get paid to rank a product first?

No. Retailer links may be affiliate links, but rankings and placement are never paid. Every product is scored by the same public model, and the ranking is recomputed from the underlying product data rather than edited by hand.

The short answer · HDL cholesterol

Take niacin for hdl cholesterol. This is the one to buy.

Life Extension, Vitamin B3 Niacin, 500 mg, 100 Capsules

4.6· 8,873 ratings· $0.06/serving

DoseRank score83

Niacin 500 mg — inside the studied 500-3000 mg window

Of 1,256 products scored for HDL cholesterol, Life Extension, Vitamin B3 Niacin, 500 mg, 100 Capsules ranks #1 with a DoseRank score of 83. Niacin is the strongest evidence signal for this outcome.

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Cheaper alternative$0.05 per servingNutricost, Niacin, Unflavored, 8.9 oz (250 g)

Retailer links may be affiliate links. Rankings and placement are never paid.

The form“Why Niacin — not Nicotinic Acid?”

Niacin is the strongest evidence signal for this outcome.

NiacinThe pick
Strong evidence · 500 mg
Vitamin B3 as nicotinic acid; a NAD+ precursor that can raise HDL but causes a prostaglandin-mediated skin flush at higher doses.
Nicotinic Acid
Strong evidence · 500 mg
The free-acid form of niacin (vitamin B3); raises HDL and lowers triglycerides at gram-level doses, but causes pronounced skin flushing that limits compliance.

Buy the #1 pick

The dose“Is the dose actually effective?”

Niacin at 500 mg lands inside the studied 500-3000 mg window.

Niacin

Studied window 500-3000 mg · this pick 500 mg

The ranking“Why should I trust this pick?”

Strong trust signals — consistently high marks from verified buyer ratings. Each product gets a DoseRank score blending clinical strength, evidence, dose fit, trust and value. Retailer links may be affiliate links — the scoring model decides placement, never payment from a brand.

1,256 products scored
Never paid placement
Evidence level: Strong · 92
220 brands
11 ingredients

See the full analysis — every score, every product How the ranking works

The price“Can I do better than $0.06 a serving?”

$0.06 per serving — mid price tier for this outcome. The cheapest ranked pick here is $0.05 per serving.

2
Nutricost, Niacin, Unflavored, 8.9 oz (250 g)Score 81 · $0.05/serving
iHerb
10
21st Century, Niacin, Prolonged Release, 110 TabletsScore 19 · $0.05/serving
iHerb

Why not the absolute cheapest? The DoseRank score also weighs clinical strength, evidence, dose fit and trust — the very cheapest listings rarely hold up everywhere else.

Ready?

The #1 pick is $0.06 a serving.

Life Extension, Vitamin B3 Niacin, 500 mg, 100 Capsules — in stock at a tracked retailer.

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Questions

Frequently asked

Life Extension, Vitamin B3 Niacin, 500 mg, 100 Capsules ranks #1 for HDL cholesterol with a DoseRank score of 83. The score blends clinical strength, evidence, dose fit, trust signals and value across 1,256 products scored for this outcome.

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