The short answer · Folate status
Take l-methylfolate for folate status. This is the one to buy.
1
Life Extension, BioActive Folate & Vitamin B12, 90 Vegetarian Capsules
4.8· 8,146 ratings· $0.09/serving
DoseRank score88
L-Methylfolate 680 mcg — inside the studied 400-1000 µg window
Of 3,053 products scored for Folate status, Life Extension, BioActive Folate & Vitamin B12, 90 Vegetarian Capsules ranks #1 with a DoseRank score of 88. L-Methylfolate is the strongest evidence signal for this outcome.
The form“Why L-Methylfolate — not 5-MTHF or Folic Acid?”Evidence Strong evidence
L-Methylfolate is the strongest evidence signal for this outcome.
- L-MethylfolateThe pick
Strong evidence · 680 mcg
The bioactive, methylated form of folate (5-MTHF) that bypasses the MTHFR conversion step; useful for those with MTHFR variants who convert folic acid poorly.
- 5-MTHF
Strong evidence · 1700 mcg
The bioactive, methylated form of folate that bypasses the MTHFR conversion step; preferred for individuals with MTHFR variants who convert folic acid poorly.
- Folic Acid
Strong evidence · 400 mcg
Synthetic, oxidized form of folate (vitamin B9); must be converted to 5-MTHF, a step impaired by MTHFR variants — methylfolate is preferred when conversion is a concern.
Questions
Frequently asked
Life Extension, BioActive Folate & Vitamin B12, 90 Vegetarian Capsules ranks #1 for Folate status with a DoseRank score of 88. The score blends clinical strength, evidence, dose fit, trust signals and value across 3,053 products scored for this outcome.
L-Methylfolate is the strongest evidence signal for this outcome.
L-Methylfolate at 680 mcg lands inside the studied 400-1000 µg window. DoseRank scores this product's dose fit at 78 out of 100.
Life Extension, BioActive Folate & Vitamin B12, 90 Vegetarian Capsules works out at $0.09 per serving. $0.09 per serving — low price tier for this outcome. Nothing else in this ranking costs less per serving.
No. Retailer links may be affiliate links, but rankings and placement are never paid. Every product is scored by the same public model, and the ranking is recomputed from the underlying product data rather than edited by hand.