The short answer · Cachexia

Optimum Nutrition, HMB, 90 Capsules (1,000 mg per Capsule)
4.4· 1,129 ratings· $1.33/serving
HMB 3 g — inside the studied 3-3 g window
Of 8,472 products scored for Cachexia, Optimum Nutrition, HMB, 90 Capsules (1,000 mg per Capsule) ranks #1 with a DoseRank score of 81. Calories leads the evidence here, backed by HMB.
Calories leads the evidence here, backed by HMB.
Moderate evidence · 3 g
Beta-hydroxy beta-methylbutyrate, a leucine metabolite; supports muscle protein synthesis and limits breakdown, most studied during caloric restriction or detraining.
Strong evidence · 15 kcal
Unit of dietary energy; total intake relative to expenditure is the primary driver of body-weight change, not a supplement to take.
Questions
Optimum Nutrition, HMB, 90 Capsules (1,000 mg per Capsule) ranks #1 for Cachexia with a DoseRank score of 81. The score blends clinical strength, evidence, dose fit, trust signals and value across 8,472 products scored for this outcome.
Calories leads the evidence here, backed by HMB.
1 of 2 dosed ingredients land in the studied range. HMB at 3 g lands inside the studied 3-3 g window. DoseRank scores this product's dose fit at 89 out of 100.
Optimum Nutrition, HMB, 90 Capsules (1,000 mg per Capsule) works out at $1.33 per serving. $1.33 per serving — high price tier for this outcome. The cheapest ranked pick here is $1.13 per serving.
No. Retailer links may be affiliate links, but rankings and placement are never paid. Every product is scored by the same public model, and the ranking is recomputed from the underlying product data rather than edited by hand.
Retailer links may be affiliate links. Rankings and placement are never paid.
1 of 2 dosed ingredients land in the studied range. HMB at 3 g lands inside the studied 3-3 g window.
HMB
Studied window 3-3 g · this pick 3 g
Calories
Studied window 2000-4000 kcal · this pick 15 kcal
Solid trust signals from buyer ratings, with room to grow. Each product gets a DoseRank score blending clinical strength, evidence, dose fit, trust and value. Retailer links may be affiliate links — the scoring model decides placement, never payment from a brand.
$1.33 per serving — high price tier for this outcome. The cheapest ranked pick here is $1.13 per serving.
Why not the absolute cheapest? The DoseRank score also weighs clinical strength, evidence, dose fit and trust — the very cheapest listings rarely hold up everywhere else.
Ready?
The #1 pick is $1.33 a serving.Optimum Nutrition, HMB, 90 Capsules (1,000 mg per Capsule) — in stock at a tracked retailer.
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