The short answer · Antioxidant capacity
Take ascorbic acid & selenomethionine for antioxidant capacity. This is the one to buy.

California Gold Nutrition, Defender 4, with Vitamin C, Vitamin D, Zinc & Selenium, 180 Veggie Capsules
4.7· 187,376 ratings· $0.06/serving
Ascorbic Acid 500 mg — inside the studied 500-1000 mg window
Of 10,649 products scored for Antioxidant capacity, California Gold Nutrition, Defender 4, with Vitamin C, Vitamin D, Zinc & Selenium, 180 Veggie Capsules ranks #1 with a DoseRank score of 95. Selenomethionine leads the evidence here, backed by Ascorbic Acid.
Retailer links may be affiliate links. Rankings and placement are never paid.
The form“Why Ascorbic Acid & Selenomethionine?”Evidence Moderate evidence
Selenomethionine leads the evidence here, backed by Ascorbic Acid.
- Ascorbic AcidThe pick
Moderate evidence · 500 mg
Pure vitamin C in its simplest acid form; effective and inexpensive, but can irritate the stomach at higher doses - buffered forms suit sensitive users.
- SelenomethionineThe pick
Strong evidence · 50 mcg
Selenium bound to methionine, the predominant natural dietary form; best-absorbed selenium supplement with efficient tissue retention, often used for thyroid and antioxidant enzyme support.
- Alpha-Lipoic Acid
Strong evidence · 25 mg
Dual-soluble antioxidant that works in both fat and water environments; supports mitochondrial energy metabolism and helps recycle vitamins C and E.
The dose“Is the dose actually effective?”Dose fit 67
2 of 2 dosed ingredients land in the studied range. Ascorbic Acid at 500 mg lands inside the studied 500-1000 mg window.
Ascorbic Acid
Studied window 500-1000 mg · this pick 500 mg
Selenomethionine
Studied window 50-200 mcg · this pick 50 mcg
The ranking“Why should I trust this pick?”Trust 93
Strong trust signals — consistently high marks from verified buyer ratings. Each product gets a DoseRank score blending clinical strength, evidence, dose fit, trust and value. Retailer links may be affiliate links — the scoring model decides placement, never payment from a brand.
- 10,649 products scored
- Never paid placement
- Evidence level: Moderate · 85
- 543 brands
- 115 ingredients
The price“Can I do better than $0.06 a serving?”Value 89
$0.06 per serving — low price tier for this outcome. Nothing else in this ranking costs less per serving.
Ready?
The #1 pick is $0.06 a serving.California Gold Nutrition, Defender 4, with Vitamin C, Vitamin D, Zinc & Selenium, 180 Veggie Capsules — in stock at a tracked retailer.
View on iHerbA saved, shareable breakdown: your matched products, dose math, and interaction flags to discuss with a clinician.
Or take the 60-sec quiz →Questions
Frequently asked
California Gold Nutrition, Defender 4, with Vitamin C, Vitamin D, Zinc & Selenium, 180 Veggie Capsules ranks #1 for Antioxidant capacity with a DoseRank score of 95. The score blends clinical strength, evidence, dose fit, trust signals and value across 10,649 products scored for this outcome.