Everything DoseRank tracks on the squalane shelf — Milk Thistle. The category itself is never ranked: 15 products get scored the moment you say what you want them to do.
How to read the scores
This legend covers the scores on this page — for data sources, scoring weights, and limits, read the full methodology →
Answer a few questions about your goals, habits, stack, and budget. Then, DoseRank will find the products that best match your needs based on your answers. It's free and only takes 60 seconds! No account is required.
A saved, shareable breakdown: your matched products, dose math, interaction flags to discuss with a clinician, and a price-tracked stack you can revisit.
Questions
Each product gets a composite score blending clinical strength, evidence, dose fit, trust and value — computed for the goal you picked, across this category's products. The #1 on the DoseRank tab has the highest composite; the other tabs re-rank the same products by Value, Trust, or Popularity. Placement is never paid.
Start with a goal, not a brand
Browsing squalane supplements without a goal makes no sense — different products do different jobs, and “best” flips depending on which job you're hiring for. These are the 42 health outcomes that matter for this category. Pick yours, and the full evidence-ranked shelf loads for that goal alone.
Aspartate aminotransferase (AST)Enzyme used to assess liver and muscle injury.2 rankedStrong
Wrinkle severityDegree of visible skin wrinkling.2 rankedModerate-strong
Eye strainVisual fatigue or discomfort from eye use.2 rankedModerate-strong
Pain intensitySeverity of pain regardless of body site.3 rankedStrong
Infection incidenceOverall rate of infectious illness.2 rankedStrong
C-reactive proteinAcute-phase inflammatory marker.4 rankedStrong
Fat oxidationUse of fat as an energy source.6 rankedModerate-strong
Alanine aminotransferase (ALT)Liver enzyme used to assess hepatocellular injury.3 rankedStrong
AppetiteDesire to eat; may be clinically favorable or unfavorable depending on context.3 rankedModerate-strong
Lactation adequacySufficient breast milk production or breastfeeding success.2 rankedLimited
Skin hydrationMoisture content or hydration of the skin.2 rankedModerate-strong
Liver functionOverall biochemical or clinical hepatic performance.3 rankedModerate-strong
ThermogenesisHeat production and metabolic energy expenditure.8 rankedStrong
Resting energy expenditureCalories burned at rest; marker of basal metabolism.8 rankedStrong
Antioxidant capacityMeasured ability to counter oxidative stress.9 rankedModerate-strongNothing is ranked yet — the shelf stays locked until you pick a goal.
No goal, no ranking.
A “best squalane supplement” list without a goal would be marketing, not evidence. Pick what you want to improve and DoseRank scores all 15 products against that goal's trials.