Everything DoseRank tracks on the spaghetti shelf. The category itself is never ranked: 18 products get scored the moment you say what you want them to do.
How to read the scores
This legend covers the scores on this page — for data sources, scoring weights, and limits, read the full methodology →
Answer a few questions about your goals, habits, stack, and budget. Then, DoseRank will find the products that best match your needs based on your answers. It's free and only takes 60 seconds! No account is required.
A saved, shareable breakdown: your matched products, dose math, interaction flags to discuss with a clinician, and a price-tracked stack you can revisit.
Questions
Each product gets a composite score blending clinical strength, evidence, dose fit, trust and value — computed for the goal you picked, across this category's products. The #1 on the DoseRank tab has the highest composite; the other tabs re-rank the same products by Value, Trust, or Popularity. Placement is never paid.
Start with a goal, not a brand
Browsing spaghetti supplements without a goal makes no sense — different products do different jobs, and “best” flips depending on which job you're hiring for. These are the 45 health outcomes that matter for this category. Pick yours, and the full evidence-ranked shelf loads for that goal alone.
Gamma-glutamyl transferase (GGT)Marker of cholestasis, alcohol exposure, or hepatic stress.1 rankedModerate-strong
Pregnancy rateFrequency of achieved pregnancies.1 rankedModerate-strong
IrritabilityLow threshold for frustration or anger.2 rankedLimited
Bone turnover markersBiochemical indicators of bone formation and resorption.3 rankedStrong
Coagulation statusOverall blood clotting tendency.2 rankedStrong
Thyroid-stimulating hormonePituitary hormone used to assess thyroid status.2 rankedStrong
Vitamin K statusBiochemical sufficiency of vitamin K.3 rankedStrong
Insulin resistanceReduced response to insulin associated with metabolic disease.5 rankedStrong
PCOS symptom burdenClinical burden of polycystic ovary syndrome symptoms.3 rankedStrong
Aspartate aminotransferase (AST)Enzyme used to assess liver and muscle injury.1 rankedStrong
Power outputAbility to generate force rapidly.2 rankedStrong
Infection incidenceOverall rate of infectious illness.2 rankedStrong
Menstrual regularityMore predictable and regular menstrual cycles.2 rankedStrong
Muscle strengthAbility of muscles to generate force.2 rankedStrong
Omega-3 indexRed blood cell EPA+DHA content reflecting omega-3 status.2 rankedStrongNothing is ranked yet — the shelf stays locked until you pick a goal.
No goal, no ranking.
A “best spaghetti supplement” list without a goal would be marketing, not evidence. Pick what you want to improve and DoseRank scores all 18 products against that goal's trials.