Everything DoseRank tracks on the skin treatment shelf — Eicosapentaenoic Acid (EPA) and Grape Seed Extract. The category itself is never ranked: 125 products get scored the moment you say what you want them to do.
How to read the scores
This legend covers the scores on this page — for data sources, scoring weights, and limits, read the full methodology →
Answer a few questions about your goals, habits, stack, and budget. Then, DoseRank will find the products that best match your needs based on your answers. It's free and only takes 60 seconds! No account is required.
A saved, shareable breakdown: your matched products, dose math, interaction flags to discuss with a clinician, and a price-tracked stack you can revisit.
Questions
Each product gets a composite score blending clinical strength, evidence, dose fit, trust and value — computed for the goal you picked, across this category's products. The #1 on the DoseRank tab has the highest composite; the other tabs re-rank the same products by Value, Trust, or Popularity. Placement is never paid.
Start with a goal, not a brand
Browsing skin treatment supplements without a goal makes no sense — different products do different jobs, and “best” flips depending on which job you're hiring for. These are the 45 health outcomes that matter for this category. Pick yours, and the full evidence-ranked shelf loads for that goal alone.
C-reactive proteinAcute-phase inflammatory marker.36 rankedStrong
Omega-3 indexRed blood cell EPA+DHA content reflecting omega-3 status.18 rankedStrong
Serum creatinineBlood marker commonly used to estimate kidney function.6 rankedStrong
Range of motionExtent of achievable joint movement.3 rankedModerate-strong
Sperm countNumber of sperm in semen.4 rankedLimited
Pregnancy rateFrequency of achieved pregnancies.2 rankedModerate-strong
Vascular functionOverall health and reactivity of the circulatory system.22 rankedStrong
Gamma-glutamyl transferase (GGT)Marker of cholestasis, alcohol exposure, or hepatic stress.1 rankedModerate-strong
Arterial stiffnessReduced elasticity of arteries associated with cardiovascular risk.19 rankedStrong
PCOS symptom burdenClinical burden of polycystic ovary syndrome symptoms.14 rankedStrong
Joint functionAbility of joints to move and support normal activity.20 rankedStrong
Aspartate aminotransferase (AST)Enzyme used to assess liver and muscle injury.5 rankedStrong
Resting heart rateBaseline heart rate measured at rest.11 rankedStrong
TriglyceridesCirculating triglyceride concentration.39 rankedStrong
Menstrual regularityMore predictable and regular menstrual cycles.11 rankedStrongNothing is ranked yet — the shelf stays locked until you pick a goal.
No goal, no ranking.
A “best skin treatment supplement” list without a goal would be marketing, not evidence. Pick what you want to improve and DoseRank scores all 125 products against that goal's trials.