Everything DoseRank tracks on the serine shelf — Lion's Mane. The category itself is never ranked: 12 products get scored the moment you say what you want them to do.
How to read the scores
This legend covers the scores on this page — for data sources, scoring weights, and limits, read the full methodology →
Answer a few questions about your goals, habits, stack, and budget. Then, DoseRank will find the products that best match your needs based on your answers. It's free and only takes 60 seconds! No account is required.
A saved, shareable breakdown: your matched products, dose math, interaction flags to discuss with a clinician, and a price-tracked stack you can revisit.
Questions
Each product gets a composite score blending clinical strength, evidence, dose fit, trust and value — computed for the goal you picked, across this category's products. The #1 on the DoseRank tab has the highest composite; the other tabs re-rank the same products by Value, Trust, or Popularity. Placement is never paid.
Start with a goal, not a brand
Browsing serine supplements without a goal makes no sense — different products do different jobs, and “best” flips depending on which job you're hiring for. These are the 13 health outcomes that matter for this category. Pick yours, and the full evidence-ranked shelf loads for that goal alone.
Brain fogSubjective cognitive slowing or reduced mental clarity.2 rankedLimited
Eye strainVisual fatigue or discomfort from eye use.2 rankedModerate-strong
Sleep qualityOverall restfulness and perceived quality of sleep.12 rankedModerate-strong
Neuropathy symptomsPain, numbness, or dysfunction due to peripheral nerve problems.9 rankedLimited
Cognitive functionOverall thinking ability including memory, attention, and processing.9 rankedModerate-strong
Dry eye symptomsIrritation, burning, or dryness of the eyes.2 rankedLimited
Night vision or dark adaptationAbility to see or adapt under low-light conditions.2 rankedLimited
MicrocirculationPerfusion in small vessels and capillary beds.2 rankedModerate-strong
Skin hydrationMoisture content or hydration of the skin.2 rankedLimited
MemoryAbility to encode, store, and retrieve information.2 rankedModerate-strong
Oxidative stress biomarkersLaboratory indicators of oxidative damage or redox imbalance.2 rankedModerate-strong
Vascular functionOverall health and reactivity of the circulatory system.2 rankedStrong
Antioxidant capacityMeasured ability to counter oxidative stress.2 rankedStrongNothing is ranked yet — the shelf stays locked until you pick a goal.
No goal, no ranking.
A “best serine supplement” list without a goal would be marketing, not evidence. Pick what you want to improve and DoseRank scores all 12 products against that goal's trials.