Everything DoseRank tracks on the mushrooms shelf — Lion's Mane. The category itself is never ranked: 643 products get scored the moment you say what you want them to do.
How to read the scores
This legend covers the scores on this page — for data sources, scoring weights, and limits, read the full methodology →
Answer a few questions about your goals, habits, stack, and budget. Then, DoseRank will find the products that best match your needs based on your answers. It's free and only takes 60 seconds! No account is required.
A saved, shareable breakdown: your matched products, dose math, interaction flags to discuss with a clinician, and a price-tracked stack you can revisit.
Questions
Each product gets a composite score blending clinical strength, evidence, dose fit, trust and value — computed for the goal you picked, across this category's products. The #1 on the DoseRank tab has the highest composite; the other tabs re-rank the same products by Value, Trust, or Popularity. Placement is never paid.
Start with a goal, not a brand
Browsing mushrooms supplements without a goal makes no sense — different products do different jobs, and “best” flips depending on which job you're hiring for. These are the 45 health outcomes that matter for this category. Pick yours, and the full evidence-ranked shelf loads for that goal alone.
Brain fogSubjective cognitive slowing or reduced mental clarity.182 rankedLimited
Kidney functionOverall renal filtration and excretory performance.156 rankedModerate-strong
Overall survivalLength of survival during follow-up; higher is better.110 rankedStrong
Aerobic capacity (VO2 max)Maximum oxygen utilization during exercise.168 rankedModerate-strong
White blood cell countNumber of circulating immune cells.110 rankedModerate-strong
Serum creatinineBlood marker commonly used to estimate kidney function.39 rankedStrong
Endurance performanceAbility to maintain effort over a prolonged duration.175 rankedStrong
MemoryAbility to encode, store, and retrieve information.197 rankedStrong
FatiguePersistent tiredness, low stamina, or lack of energy.457 rankedModerate-strong
Anxiety symptomsWorry, tension, fear, or related anxiety manifestations.216 rankedStrong
Microbiome diversityEcologic diversity of gut microbial communities.38 rankedModerate-strong
LDL cholesterolLow-density lipoprotein cholesterol; lower is often preferred.280 rankedStrong
Cognitive functionOverall thinking ability including memory, attention, and processing.281 rankedModerate-strong
Neuropathy symptomsPain, numbness, or dysfunction due to peripheral nerve problems.192 rankedStrong
Sexual functionOverall sexual performance and satisfaction.44 rankedModerate-strongNothing is ranked yet — the shelf stays locked until you pick a goal.
No goal, no ranking.
A “best mushrooms supplement” list without a goal would be marketing, not evidence. Pick what you want to improve and DoseRank scores all 643 products against that goal's trials.