Everything DoseRank tracks on the lysine shelf — L-Lysine. The category itself is never ranked: 74 products get scored the moment you say what you want them to do.
How to read the scores
This legend covers the scores on this page — for data sources, scoring weights, and limits, read the full methodology →
Answer a few questions about your goals, habits, stack, and budget. Then, DoseRank will find the products that best match your needs based on your answers. It's free and only takes 60 seconds! No account is required.
A saved, shareable breakdown: your matched products, dose math, interaction flags to discuss with a clinician, and a price-tracked stack you can revisit.
Questions
Each product gets a composite score blending clinical strength, evidence, dose fit, trust and value — computed for the goal you picked, across this category's products. The #1 on the DoseRank tab has the highest composite; the other tabs re-rank the same products by Value, Trust, or Popularity. Placement is never paid.
Start with a goal, not a brand
Browsing lysine supplements without a goal makes no sense — different products do different jobs, and “best” flips depending on which job you're hiring for. These are the 39 health outcomes that matter for this category. Pick yours, and the full evidence-ranked shelf loads for that goal alone.
Infection durationLength of infectious illness episodes.70 rankedModerate-strong
Anxiety symptomsWorry, tension, fear, or related anxiety manifestations.70 rankedModerate-strong
Vitamin C statusBiochemical sufficiency of ascorbic acid.13 rankedStrong
Arterial stiffnessReduced elasticity of arteries associated with cardiovascular risk.14 rankedModerate-strong
Uric acidPurine metabolism marker associated with gout and cardiometabolic risk.13 rankedModerate-strong
Skin elasticityAbility of skin to stretch and recoil.9 rankedLimited
Vascular functionOverall health and reactivity of the circulatory system.6 rankedModerate-strong
Wound healingSpeed and quality of tissue repair.14 rankedModerate-strong
Hot flashesEpisodes of sudden heat sensation commonly related to menopause.3 rankedModerate-strong
Zinc statusBiochemical sufficiency of zinc.6 rankedStrong
Common cold durationLength of cold episodes.16 rankedStrong
Antioxidant capacityMeasured ability to counter oxidative stress.19 rankedStrong
Oxidative stress biomarkersLaboratory indicators of oxidative damage or redox imbalance.9 rankedModerate-strong
Niacin statusBiochemical sufficiency of vitamin B3.4 rankedStrong
EdemaSwelling due to excess fluid accumulation.7 rankedModerate-strongNothing is ranked yet — the shelf stays locked until you pick a goal.
No goal, no ranking.
A “best lysine supplement” list without a goal would be marketing, not evidence. Pick what you want to improve and DoseRank scores all 74 products against that goal's trials.