Everything DoseRank tracks on the lions mane shelf — Lion's Mane. The category itself is never ranked: 159 products get scored the moment you say what you want them to do.
How to read the scores
This legend covers the scores on this page — for data sources, scoring weights, and limits, read the full methodology →
Answer a few questions about your goals, habits, stack, and budget. Then, DoseRank will find the products that best match your needs based on your answers. It's free and only takes 60 seconds! No account is required.
A saved, shareable breakdown: your matched products, dose math, interaction flags to discuss with a clinician, and a price-tracked stack you can revisit.
Questions
Each product gets a composite score blending clinical strength, evidence, dose fit, trust and value — computed for the goal you picked, across this category's products. The #1 on the DoseRank tab has the highest composite; the other tabs re-rank the same products by Value, Trust, or Popularity. Placement is never paid.
Start with a goal, not a brand
Browsing lions mane supplements without a goal makes no sense — different products do different jobs, and “best” flips depending on which job you're hiring for. These are the 45 health outcomes that matter for this category. Pick yours, and the full evidence-ranked shelf loads for that goal alone.
Brain fogSubjective cognitive slowing or reduced mental clarity.109 rankedLimited
MemoryAbility to encode, store, and retrieve information.118 rankedModerate-strong
Anxiety symptomsWorry, tension, fear, or related anxiety manifestations.116 rankedStrong
Cognitive functionOverall thinking ability including memory, attention, and processing.128 rankedModerate-strong
Neuropathy symptomsPain, numbness, or dysfunction due to peripheral nerve problems.114 rankedLimited
LDL cholesterolLow-density lipoprotein cholesterol; lower is often preferred.66 rankedStrong
Depressive symptomsLow mood, anhedonia, and related depressive features.124 rankedStrong
SatietySense of fullness after eating.61 rankedModerate-strong
Oral healthOverall condition of the mouth, teeth, and gums.5 rankedModerate-strong
ConstipationInfrequent, difficult, or hard bowel movements.57 rankedStrong
FatiguePersistent tiredness, low stamina, or lack of energy.80 rankedModerate-strong
ThermogenesisHeat production and metabolic energy expenditure.49 rankedStrong
Resting energy expenditureCalories burned at rest; marker of basal metabolism.49 rankedStrong
Calmness or relaxationReduced tension and greater sense of calm.6 rankedStrong
Attention and concentrationAbility to sustain and direct focus.11 rankedModerate-strongNothing is ranked yet — the shelf stays locked until you pick a goal.
No goal, no ranking.
A “best lions mane supplement” list without a goal would be marketing, not evidence. Pick what you want to improve and DoseRank scores all 159 products against that goal's trials.