Everything DoseRank tracks on the highlighter shelf. The category itself is never ranked: 33 products get scored the moment you say what you want them to do.
How to read the scores
This legend covers the scores on this page — for data sources, scoring weights, and limits, read the full methodology →
Answer a few questions about your goals, habits, stack, and budget. Then, DoseRank will find the products that best match your needs based on your answers. It's free and only takes 60 seconds! No account is required.
A saved, shareable breakdown: your matched products, dose math, interaction flags to discuss with a clinician, and a price-tracked stack you can revisit.
Questions
Each product gets a composite score blending clinical strength, evidence, dose fit, trust and value — computed for the goal you picked, across this category's products. The #1 on the DoseRank tab has the highest composite; the other tabs re-rank the same products by Value, Trust, or Popularity. Placement is never paid.
Start with a goal, not a brand
Browsing highlighter supplements without a goal makes no sense — different products do different jobs, and “best” flips depending on which job you're hiring for. These are the 45 health outcomes that matter for this category. Pick yours, and the full evidence-ranked shelf loads for that goal alone.
Range of motionExtent of achievable joint movement.1 rankedModerate-strong
Wrinkle severityDegree of visible skin wrinkling.3 rankedStrong
IrritabilityLow threshold for frustration or anger.3 rankedLimited
Joint stiffnessReduced ease of joint movement, especially after rest.4 rankedModerate-strong
TolerabilityOverall ability to continue the intervention without unacceptable side effects.2 rankedModerate-strong
Lean body massNon-fat body mass, often used as a marker of preserved musculature.9 rankedStrong
Muscle massQuantity of skeletal muscle tissue.10 rankedStrong
Congenital anomalyStructural or functional birth defect.5 rankedStrong
Nail strengthResistance of nails to splitting or breaking.5 rankedModerate-strong
Riboflavin statusBiochemical sufficiency of vitamin B2.4 rankedStrong
Folate statusBiochemical sufficiency of folate.5 rankedStrong
Skin elasticityAbility of skin to stretch and recoil.4 rankedStrong
Iodine statusBiochemical sufficiency of iodine.3 rankedStrong
Vitamin B12 statusBiochemical sufficiency of cobalamin.6 rankedStrong
Niacin statusBiochemical sufficiency of vitamin B3.4 rankedStrongNothing is ranked yet — the shelf stays locked until you pick a goal.
No goal, no ranking.
A “best highlighter supplement” list without a goal would be marketing, not evidence. Pick what you want to improve and DoseRank scores all 33 products against that goal's trials.