Everything DoseRank tracks on the berberine shelf — Berberine and Inositol. The category itself is never ranked: 216 products get scored the moment you say what you want them to do.
How to read the scores
This legend covers the scores on this page — for data sources, scoring weights, and limits, read the full methodology →
Answer a few questions about your goals, habits, stack, and budget. Then, DoseRank will find the products that best match your needs based on your answers. It's free and only takes 60 seconds! No account is required.
A saved, shareable breakdown: your matched products, dose math, interaction flags to discuss with a clinician, and a price-tracked stack you can revisit.
Questions
Each product gets a composite score blending clinical strength, evidence, dose fit, trust and value — computed for the goal you picked, across this category's products. The #1 on the DoseRank tab has the highest composite; the other tabs re-rank the same products by Value, Trust, or Popularity. Placement is never paid.
Start with a goal, not a brand
Browsing berberine supplements without a goal makes no sense — different products do different jobs, and “best” flips depending on which job you're hiring for. These are the 45 health outcomes that matter for this category. Pick yours, and the full evidence-ranked shelf loads for that goal alone.
PCOS symptom burdenClinical burden of polycystic ovary syndrome symptoms.152 rankedModerate-strong
Insulin resistanceReduced response to insulin associated with metabolic disease.171 rankedStrong
HbA1cAverage blood glucose marker over prior months.161 rankedStrong
Hepatic steatosisExcess fat accumulation in the liver.166 rankedModerate-strong
TriglyceridesCirculating triglyceride concentration.179 rankedStrong
LDL cholesterolLow-density lipoprotein cholesterol; lower is often preferred.186 rankedStrong
Fasting blood glucoseBlood glucose after fasting.172 rankedStrong
Aspartate aminotransferase (AST)Enzyme used to assess liver and muscle injury.14 rankedStrong
Psoriasis severityExtent or severity of psoriatic skin disease.5 rankedModerate-strong
AppetiteDesire to eat; may be clinically favorable or unfavorable depending on context.35 rankedModerate-strong
Ketone levelsCirculating ketone concentrations, relevant in fasting or ketogenic states.6 rankedStrong
C-reactive proteinAcute-phase inflammatory marker.30 rankedStrong
Fat oxidationUse of fat as an energy source.49 rankedModerate-strong
Alanine aminotransferase (ALT)Liver enzyme used to assess hepatocellular injury.23 rankedStrong
Liver functionOverall biochemical or clinical hepatic performance.21 rankedStrongNothing is ranked yet — the shelf stays locked until you pick a goal.
No goal, no ranking.
A “best berberine supplement” list without a goal would be marketing, not evidence. Pick what you want to improve and DoseRank scores all 216 products against that goal's trials.