Everything DoseRank tracks on the alpha lipoic acid shelf — Sodium R-Lipoate, Pyridoxine HCl and Acetyl-L-Carnitine. The category itself is never ranked: 189 products get scored the moment you say what you want them to do.
How to read the scores
This legend covers the scores on this page — for data sources, scoring weights, and limits, read the full methodology →
Answer a few questions about your goals, habits, stack, and budget. Then, DoseRank will find the products that best match your needs based on your answers. It's free and only takes 60 seconds! No account is required.
A saved, shareable breakdown: your matched products, dose math, interaction flags to discuss with a clinician, and a price-tracked stack you can revisit.
Questions
Each product gets a composite score blending clinical strength, evidence, dose fit, trust and value — computed for the goal you picked, across this category's products. The #1 on the DoseRank tab has the highest composite; the other tabs re-rank the same products by Value, Trust, or Popularity. Placement is never paid.
Start with a goal, not a brand
Browsing alpha lipoic acid supplements without a goal makes no sense — sodium r-lipoate, pyridoxine hcl and acetyl-l-carnitine do different jobs, and “best” flips depending on which job you're hiring for. These are the 45 health outcomes that matter for this category. Pick yours, and the full evidence-ranked shelf loads for that goal alone.
Neuropathy symptomsPain, numbness, or dysfunction due to peripheral nerve problems.160 rankedStrong
Insulin sensitivityEfficiency of tissue response to insulin.162 rankedStrong
Inflammation biomarkersLaboratory measures of systemic or local inflammation.130 rankedModerate-strong
Antioxidant capacityMeasured ability to counter oxidative stress.172 rankedStrong
Fasting blood glucoseBlood glucose after fasting.163 rankedStrong
Oxidative stress biomarkersLaboratory indicators of oxidative damage or redox imbalance.65 rankedStrong
Behavioral symptomsUndesired behavioral disturbances such as agitation or impulsivity.2 rankedLimited
Hair shedding or lossExcess hair loss relative to normal cycling.23 rankedLimited
Biotin statusBiochemical sufficiency of biotin.20 rankedStrong
Phosphate statusBiochemical phosphate balance.11 rankedStrong
Nail brittlenessFragility or easy breakage of nails.23 rankedLimited
Respiratory symptom burdenOverall severity of breathing-related symptoms.6 rankedModerate-strong
Aspartate aminotransferase (AST)Enzyme used to assess liver and muscle injury.5 rankedStrong
Platelet functionPlatelet activity relevant to clotting and bleeding.4 rankedLimited
Asthma controlDegree to which asthma symptoms and exacerbations are minimized.4 rankedLimitedNothing is ranked yet — the shelf stays locked until you pick a goal.
No goal, no ranking.
A “best alpha lipoic acid supplement” list without a goal would be marketing, not evidence. Pick what you want to improve and DoseRank scores all 189 products against that goal's trials.