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DOSERANKEVIDENCE-BASED SUPPLEMENTSFull analysis

The short answer · Fracture risk

Take vitamin d3 (cholecalciferol) & calcium carbonate for fracture risk. This is the one to buy.

21st Century, Calcium Plus D3, 90 Tablets
1

21st Century, Calcium Plus D3, 90 Tablets

4.7· 11,111 ratings· $0.07/serving

DoseRank score92

Calcium Carbonate 1000 mg — inside the studied 1000-1500 mg window

Of 6,470 products scored for Fracture risk, 21st Century, Calcium Plus D3, 90 Tablets ranks #1 with a DoseRank score of 92. Vitamin D3 (Cholecalciferol) and Calcium Carbonate are the strongest evidence signals for this outcome.

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Cheaper alternative$0.03 per serving21st Century, 600+D3, Calcium & Vitamin D3 Supplement, 400 Tablets

Retailer links may be affiliate links. Rankings and placement are never paid.

The form“Why Vitamin D3 (Cholecalciferol) & Calcium Carbonate?”Evidence Strong evidence

Vitamin D3 (Cholecalciferol) and Calcium Carbonate are the strongest evidence signals for this outcome.

  • Vitamin D3 (Cholecalciferol)The pick

    Strong evidence · 20 mcg

    The form made by skin on sun exposure and used in most supplements; converts to active calcitriol and raises serum 25(OH)D more effectively than D2.

  • Calcium CarbonateThe pick

    Strong evidence · 1000 mg

    The cheapest, most concentrated calcium form at 40% elemental; needs stomach acid, so take with food and expect weak uptake on acid-reducing medications.

  • Calcium Citrate

    Strong evidence · 1000 mg

    Calcium bound to citric acid; absorbed well even without food or with low stomach acid, so it suits older adults and PPI users.

Buy the #1 pick
The dose“Is the dose actually effective?”Dose fit 56

Calcium Carbonate at 1000 mg lands inside the studied 1000-1500 mg window.

Calcium Carbonate

Studied window 1000-1500 mg · this pick 1000 mg

The ranking“Why should I trust this pick?”Trust 93

Strong trust signals — consistently high marks from verified buyer ratings. Each product gets a DoseRank score blending clinical strength, evidence, dose fit, trust and value. Retailer links may be affiliate links — the scoring model decides placement, never payment from a brand.

  • 6,470 products scored
  • Never paid placement
  • Evidence level: Strong · 92
  • 525 brands
  • 18 ingredients
See the full analysis — every score, every productHow the ranking works
The price“Can I do better than $0.07 a serving?”Value 88

$0.07 per serving — low price tier for this outcome. Nothing else in this ranking costs less per serving.

Ready?

The #1 pick is $0.07 a serving.

21st Century, Calcium Plus D3, 90 Tablets — in stock at a tracked retailer.

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21st Century, Calcium Plus D3, 90 Tablets ranks #1 for Fracture risk with a DoseRank score of 92. The score blends clinical strength, evidence, dose fit, trust signals and value across 6,470 products scored for this outcome.

Vitamin D3 (Cholecalciferol) and Calcium Carbonate are the strongest evidence signals for this outcome.

Calcium Carbonate at 1000 mg lands inside the studied 1000-1500 mg window. DoseRank scores this product's dose fit at 56 out of 100.

21st Century, Calcium Plus D3, 90 Tablets works out at $0.07 per serving. $0.07 per serving — low price tier for this outcome. Nothing else in this ranking costs less per serving.

No. Retailer links may be affiliate links, but rankings and placement are never paid. Every product is scored by the same public model, and the ranking is recomputed from the underlying product data rather than edited by hand.

Keep exploring

Other outcomes

  • Bone mineral densityMeasure of bone strength and mineralization.
  • Bone turnover markersBiochemical indicators of bone formation and resorption.

Use rankings as research support

DoseRank rankings are informational and not medical advice. If you are pregnant, breastfeeding, using medications, or managing a health condition, ask a qualified clinician whether a supplement fits your situation. Stop use and report concerning adverse events to a clinician, the product maker, or the retailer.

Disclosure

Retailer links may be affiliate links. Rankings and placement are not paid placement.

21st Century, Calcium Plus D3, 90 Tablets

$0.07/serving · ★ 4.7 · In stock

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